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Myrbetriq

Generic Name: mirabegron (MIR a BEG ron)
Brand Names: Myrbetriq

Medically reviewed by Kaci Durbin, MD Last updated on Feb 18, 2019.

What is Myrbetriq?

Myrbetriq (mirabegron) relaxes the muscles of the urinary bladder, reducing bladder spasms.

Myrbetriq is used to treat the symptoms of overactive bladder, such as frequent or urgent urination and urinary incontinence.

Myrbetriq is often used in combination with another overactive bladder medicine, solifenacin.

Myrbetriq may also be used for purposes not listed in this medication guide.

Important information

You should not use Myrbetriq if you have

  • an allergy to Myrbetriq or mirabegron;
  • end stage renal disease (kidney failure)
  • severe kidney disease; or
  • severe uncontrolled high blood pressure.

A condition called angioedema can occur after taking Myrbetriq. Angioedema is a condition that leads to face, lip, tongue, throat swelling, difficulty breathing and can be fatal. Seek emergency attention immediately if these symptoms occur.

It may take up to 8 weeks before your symptoms improve. Keep using this medicine as directed and tell your doctor if your symptoms do not improve after 8 weeks of treatment.

Before taking this medicine

You should not use Myrbetriq if you are allergic to mirabegron, or if you have:

  • end stage renal disease (kidney failure);

  • severe liver disease; or

  • severe uncontrolled high blood pressure.

To make sure this medicine is safe for you, tell your doctor if you have:

  • kidney disease;

  • liver disease;

  • high blood pressure; or

  • trouble emptying your bladder (very little urine or a weak stream of urine).

It is not known whether Myrbetriq will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether Myrbetriq passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.

Myrbetriq is not approved for use by anyone younger than 18 years old.

How should I take Myrbetriq?

Myrbetriq is usually taken once per day. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

You may take Myrbetriq with or without food.

Take this medicine with a full glass of water.

Do not crush, chew, or break Myrbetriq. Swallow it whole.

Your blood pressure will need to be checked often while taking Myrbetriq.

It may take up to 8 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve.

Store at room temperature away from moisture and heat.

Myrbetriq dosing information

Usual Adult Dose for Urinary Incontinence and Urinary Frequency:

Initial dose: 25 mg orally once daily

Maintenance dose: 25 to 50 mg orally once daily based on individual patient efficacy and tolerability.

What happens if I miss a dose?

Skip the missed dose and wait until your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Myrbetriq?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Myrbetriq side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Myrbetriq: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • fast or pounding heartbeat;

  • pain or burning when you urinate;

  • painful or difficult urination; or

  • severe headache, blurred vision, pounding in your neck or ears, nosebleed, anxiety, confusion, severe chest pain, shortness of breath, irregular heartbeats.

Common Myrbetriq side effects may include:

  • increased blood pressure;

  • headache, dizziness;

  • cold symptoms such as stuffy nose, sneezing, sore throat; or

  • constipation, diarrhea.

  • dry mouth; or.

  • back pain, joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Myrbetriq?

Tell your doctor about all your current medicines and any you start or stop using during your treatment with Myrbetriq, especially:

  • digoxin;

  • flecainide;

  • warfarin (Coumadin, Jantoven);

  • propafenone; or

  • thioridazine.

  • metoprolol; or

  • desipramine.

This list is not complete. Other drugs may interact with Myrbetriq, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medicine only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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