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VESIcare

Generic Name: solifenacin (sol ee FEN a sin)
Brand Names: VESIcare

Medically reviewed by Sanjai Sinha, MD Last updated on Jun 14, 2019.

What is solifenacin?

Solifenacin is used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

Solifenacin may also be used for purposes not listed in this medication guide.

Important Information

You should not use this medicine if you have untreated or uncontrolled narrow-angle glaucoma, a blockage in your digestive tract (stomach or intestines), or if you are unable to urinate.

Before taking this medicine

You should not use solifenacin if you are allergic to it, or if you have:

  • untreated or uncontrolled narrow-angle glaucoma;

  • a stomach disorder causing delayed emptying; or

  • if you are unable to urinate.

Tell your doctor if you have ever had:

  • glaucoma;

  • liver disease;

  • kidney disease;

  • trouble emptying your bladder (or you have a weak stream of urine);

  • slow digestion;

  • a blockage in your stomach or intestines; or

  • long QT syndrome.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

You should not breastfeed while using solifenacin.

Solifenacin is not approved for use by anyone younger than 18 years old.

How should I take solifenacin?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Solifenacin is usually taken once per day with or without food. Follow your doctor's instructions.

Take this medicine with water.

Do not crush, chew, or break the tablet. Swallow it whole.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Take the missed dose on the same day you remember it. Take your next dose at the regular time the next day and stay on your once-daily schedule.

Do not take 2 doses on the same day.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking solifenacin?

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Solifenacin can decrease perspiration and you may be more prone to heat stroke.

Solifenacin side effects

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).

Stop using solifenacin and call your doctor at once if you have:

  • severe stomach pain, or constipation for 3 days or longer;

  • pain or burning when you urinate;

  • confusion, hallucinations;

  • vision changes, eye pain, or seeing halos around lights;

  • little or no urination;

  • dehydration symptoms--feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; or

  • high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.

Common side effects may include:

  • blurred vision;

  • dry mouth;

  • pain or burning when you urinate;

  • constipation; or

  • heat stroke--decreased sweating, dizziness, tiredness, nausea, feeling hot.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect solifenacin?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect solifenacin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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