VESIcare Side Effects

Generic name: solifenacin

Medically reviewed by Drugs.com. Last updated on Oct 31, 2023.

Note: This document provides detailed information about VESIcare.

Applies to solifenacin: oral suspension, oral tablet Side Effects associated with solifenacin. Some dosage forms listed on this page may not apply specifically to the brand name VESIcare.

Applies to solifenacin: oral suspension, oral tablet.

Precautions

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to check for unwanted effects.

Solifenacin may cause serious types of allergic reactions called angioedema and anaphylaxis, which may be life-threatening and require immediate medical attention. Check with your doctor right away if you have a rash, itching, a large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs, trouble breathing, or chest tightness while you are using this medicine.

This medicine may cause some people to become dizzy, drowsy, or have blurred vision. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine may make you sweat less, causing your body temperature to increase. Use extra care not to become overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heat stroke.

This medicine may cause constipation. Call your doctor if you get severe stomach pain or become constipated for 3 or more days.

This medicine may cause dry mouth. For temporary relief of mouth dryness, use sugarless candy or gum, melt bits of ice in your mouth, or use a saliva substitute. However, if your mouth continues to feel dry for more than 2 weeks, check with your medical doctor or dentist.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Serious side effects of VESIcare

Along with its needed effects, solifenacin (the active ingredient contained in VESIcare) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking solifenacin:

Other side effects of VESIcare

Some side effects of solifenacin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

For healthcare professionals

Applies to solifenacin: oral suspension, oral tablet.

Gastrointestinal adverse events

• Very common (10% or more): Dry mouth (up to 28%), constipation (up to 13%)
• Common (1% to 10%): Nausea, dyspepsia, upper abdominal pain, vomiting
• Uncommon (0.1% to 1%): Gastroesophageal reflux disease, dry throat, flatulence, throat irritation, eructation, thirst
• Rare (less than 0.1%): Colonic obstruction, fecal impaction
• Postmarketing reports: Ileus^[Ref]

Respiratory

• Common (1% to 10%): Pharyngitis, cough, sinusitis, bronchitis
• Uncommon (0.1% to 1%): Nasal dryness
• Postmarketing reports: Dysphonia^[Ref]

Psychiatric

• Common (1% to 10%): Depression
• Postmarketing reports: Confusion, hallucinations, delirium, somnolence^[Ref]

Ocular

• Common (1% to 10%): Blurred vision, dry eyes
• Very rare (less than 0.01%): Glaucoma^[Ref]

Genitourinary

• Common (1% to 10%): Urinary tract infection, urinary retention
• Uncommon (0.1% to 1%): Cystitis, suprapubic pain, bladder pain, micturition urgency^[Ref]

Cardiovascular

• Common (1% to 10%): Lower limb edema, hypertension
• Uncommon (0.1% to 1%): Syncope, chest tightness, hot flushes
• Postmarketing reports: Peripheral edema, QT prolongation, Torsade de Pointes, atrial fibrillation, tachycardia, palpitations, atrial fibrillation^[Ref]

Dermatologic

• Uncommon (0.1% to 1%): Dry skin
• Rare (0.01% to 0.1%): Pruritus, rash
• Very rare (less than 0.01%): Erythema multiforme, urticaria, angioedema, exfoliative dermatitis^[Ref]

Immunologic

• Common (1% to 10%): Influenza^[Ref]

Metabolic

• Very rare (less than 0.01%): Decreased appetite, hyperkalemia^[Ref]

Hypersensitivity

• Very rare (less than 0.01%): Hypersensitivity reactions (including angioedema with airway obstruction, rash, pruritus, urticaria, and anaphylactic reaction)^[Ref]

Other

• Common (1% to 10%): Fatigue^[Ref]

Renal

• Very rare (less than 0.01%): Renal impairment^[Ref]

Hepatic

• Postmarketing reports: Abnormal liver function tests, AST (aspartate aminotransferase), ALT (alanine aminotransferase), GGT (gamma-glutamyl transferase)^[Ref]

Musculoskeletal

• Common (1% to 10%): Arthralgia, back pain
• Uncommon (0.1% to 1%): Neck pain
• Postmarketing reports: Muscular weakness^[Ref]

Nervous system

• Common (1% to 10%): Dizziness, insomnia
• Uncommon (0.1% to 1%): Dysgeusia
• Rare (0.01% to 0.1%): Headache
• Postmarketing reports: Headache, tremors^[Ref]

See also:

Further information

VESIcare side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer