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User Reviews for Estradiol

Also known as: Estrace Vaginal Cream, Estring, Imvexxy, Vagifem, Yuvafem

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

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Condition Avg. Ratings Reviews Compare
Atrophic Vaginitis
5.3
   
166 reviews 52 medications
Atrophic Urethritis
5.3
   
18 reviews 46 medications
Summary of Estradiol reviews 5.5 184 reviews

Reviews for Estradiol

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Vagifem (estradiol) for Atrophic Vaginitis: "Insufficient insertion instructions. Inside of applicator came away from the outside once. It says the tablets won't fall out when you stand up, but first three times, my cervix must have pushed it straight out. Tried using them at bed-time, only to find them on sheet in morning. Tried again at bed-time, only to find tablet stuck, half melted, to tip of my cervix next day. Slight stinging sensation at first; when that stops, it's probably because tablet has fallen out. No instructions for pessary-wearers, presumably we remove the pessary before administering; the only method I haven't tried yet is putting tablet in, followed immediately by inserting pessary, but that would defeat the object, I imagine, leaving me dry and sore beneath. I don't care for throw-away applicators; it seems a waste of plastic not to wash and re-use them. Doctor said to stay on these for life, but I can't see the point if they won't stay in. Liquid or ointment would be better."

   
1.0

Eliza July 15, 2018

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Estring (estradiol) for Atrophic Vaginitis: "I've absolutely stop looking and spending money on lubes, vitamins, etc I'm 46 and all my lab work comes back normal but my yoni says different. I'm way too active to let vaginal dryness stop my life. I decided to get the Estring after a couple of years of battling with dryness and it was the BEST decision of my life. After 2 weeks my yoni has no more dryness. No lube needed to start! We just go whenever we feel like it. Best decision I've ever made. Go for it if you're tired of googling and dryness."

   
10

Camii (taken for less than 1 month) July 11, 2018

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Imvexxy (estradiol) for Atrophic Vaginitis: "I have been taking this suppository for the last 15 years in Europe and it prevented dryness and shrinking. I am mid 70 and my moisture has not changed."

   
10

Wenglowski (taken for 10 years or more) July 10, 2018

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Estring (estradiol) for Atrophic Vaginitis: "I was on this for vaginal dryness and painful intercourse. I inserted it on Wednesday but had to remove it by Sunday because it was causing back pain and cramping. I also had a “full” feeling in my vagina and I could feel the ring in there. I was hopeful for this and I like the convenience. But it’s too rigid and hard and uncomfortable. I’ve tried the vag creams and they are so messy. So not sure what to do now. The side effects are just not worth it."

   
1.0

Sb July 8, 2018

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For Atrophic Vaginitis: "Dr prescribed Premarin (conjugated estrogens) Cream. Insurance denied, ended up with Estradiol. One pea sized external application and I had heavy headed feeling and dizzy and intense vulva burning!!! Tried to wash off and felt like broken glass there!! Leg pain!! Dr says very unusual reaction. Feeling defeated!! Why????"

   
1.0

Mimi68 (taken for less than 1 month) July 6, 2018

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Yuvafem (estradiol) for Atrophic Vaginitis: "This medication is terrible. Applicators are worthless and do not dispense the tablets. I was on vagifem and had no problems whatsoever... Insurance company stated I had to go to yuvafem. Constant achy feeling, constant feeling of needing to urinate. It's so frustrating. For me to go back to vagifem my copay is $180 which I cannot afford. My physician even wrote the insurance company a letter stating that it was medically necessary for me to use the vagifem due to the side effects of the yuvafem but that I needed it at the generic cost. Of course insurance company says no way. "

   
1.0

Ginger (taken for 1 to 6 months) June 28, 2018

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Yuvafem (estradiol) for Atrophic Vaginitis: "I have been using Yuvafem for one month. As soon as I used the product, that night, I woke up with hot flashes. I am 74 years old. I don' t think hot flashes is a good reaction to this product. Going to try to get original vagifem back."

   
1.0

Gloria (taken for 1 to 6 months) June 24, 2018

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "For those who commented about burning from using Estrace...I also had burning from it. My research led me to believe that the propylene glycol and/or glycerin in the product were the culprits. I switched to a hypoallergenic form of estradiol from a good compounding pharmacy and that solved the problem. No burning and the estradiol was so helpful."

   
9.0

Anon (taken for 2 to 5 years) June 19, 2018

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Yuvafem (estradiol) for Atrophic Vaginitis: "Used Vagifem for many years=excellent product. Insurance then switched to Yuvafem=obvious cheaper packaging & lesser quality applicator, but still effective medication for me. Then insurance switched me to Teva=nightmare of product to use due to defective applicator. Now insurance has switched back to Yuvafem, but now pharmacy has been telling me for 3 months that company says out if stock. !!!"

Mandilyn June 9, 2018

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Yuvafem (estradiol) for Atrophic Vaginitis: "Unusual discharge which eventually stopped after I stopped using medication."

   
1.0

Lioness (taken for less than 1 month) May 25, 2018

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For Atrophic Vaginitis: "While Yuvafem is hardly packaged well (foil tears open and can't separate) which is as bad with Teva, the Teva brand is outright defective. The prong snaps and the tablet doesn't release! At least 2 of the 8 in the package. I didn't bother with the rest. Not to mention the awkward bulky cheap applicator itself. Total waste! I prefer Yuvafem to this poorly made product. I also pay a high out of pocket deductible and its outrageous that generic Yuvafem is now priced to match what I was paying for brand name Vagifem! What a war in women. Priced like Viagra but I don't use it for anything but dryness to prevent yeast infection. Never use TEVA. I told my pharmacist to never give me that again."

   
3.0

Redbaron (taken for 2 to 5 years) May 10, 2018

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Yuvafem (estradiol) for Atrophic Vaginitis: "Never had a problem with the drug or the packaging. I think the packaging is very hygienic and no pills fell out of the applicator. The medicine works for me. Only problem is the very high price since Medicare and my insurance do not pay anything toward the price of the drug. As a generic, I hope the price comes down as I will be on this medication indefinitely."

Junebug (taken for 1 to 6 months) May 8, 2018

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For Atrophic Vaginitis: "If men had to use this to have pain free sex, there would be no problem with overpopulation. The applicator is expected to be used for a month , but is impossible to clean thoroughly. Why not a vaginal suppository like with the treatment drugs for yeast infections? Every time I use this I have hot flashes through the night. Plus the added pleasure of having it seep out throughout the next day. I'm sorry, but this sucks!!!!!!!"

   
1.0

dh (taken for 1 to 2 years) May 8, 2018

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For Atrophic Vaginitis: "All negative posts regarding TEVA estradiol are accurate. I, too have experienced, the cheap packaging, UTI recurrences, all vaginal atrophy symptoms returning, and vaginal discharge requiring panty liners. There is no way this is the identical composition of Vagifem. NO WAY. Shame on insurance companies forcing this substandard generic on women with vaginal atrophy. I was on Vagifem for several years, with no problems. Perhaps if all of us experiencing the return of our burning and painful symptoms were in the same room with all of them who created this TEVA pill and applicator, they would witness first hand the ineffectiveness of their product. I have contacted my doctor and my pharmacy. I am insisting they discontinue TEVA and rewrite my presciption for Vagifem, no matter the cost. I hope more women do the same."

   
1.0

Anonymous (taken for 1 to 6 months) April 22, 2018

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "I’ve only been on estrace for a week, my symptoms? Hot flashes day and night, mood swings, I’d go up to the bedrooms and feel my heart palpitating, low energy, have a hard time getting up in the morning, no interest in anything. This cream is heaven sent, I’m looking forward to the next couple of weeks, have faith that it can only get better. I feel like a human being. I was honestly feeling like I was losing whom I am. I’ll keep you guys posted..."

   
9.0

Rachel (taken for less than 1 month) April 19, 2018

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Yuvafem (estradiol) for Atrophic Vaginitis: "The packaging is ok. Could be better. Insurance covers (generic). I have been taking this for almost 2 months and my joints in my legs are killing me. I was wondering if anyone else was experiencing this side affect."

   
5.0

Nan l (taken for 1 to 6 months) April 9, 2018

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For Atrophic Vaginitis: "Similar to others, have had a poor experience with TEVA's generic version. I followed my pharmacist's recommendation & called TEVA to report. TEVA's customer service was very responsive. I described how the applicator was defective & gave the lot number on the box. They sent my pharmacy a replacement package of 8 applications. Vagifem was excellent, BUT is now too expensive because it's not covered by my insurance. Yuvafem was OK.. applicator not as good as Vagifem yet better than TEVA's product. Waiting for my pharmacist's distributor to be able to restock Yuvafem."

   
4.0

Anonymous (taken for 1 to 6 months) April 3, 2018

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Estrace Vaginal Cream (estradiol) for Atrophic Urethritis: "I have been using Estrace for 5 yrs -a complete hysterectomy at age 42-can't live without it-no more nightmares, nerves are calm normallly according to my husband-HA! & don't have hot flashes. I am fortunate that my insurance has always covered It but in Jan 2018,a generic came out & my insurance would only pay for the generic. I was fine with that- but two months later I realized the generic was not working. All my symptoms had returned full blown! My husband told me to go to pharmacy and pay whatever the name brand Estrace costs! It would have been $325!! I told the Pharmacist my symptoms on the generic and he called my insurance company- told them I had had a reaction to generic-they then covered the name brand - within 24 hours I felt like a new person and better each day. I want to say here-the generic did not work for me. Keep working it women-there IS A way to have a GREAT AND HAPPY LIFE after menopause!"

   
10

Den (taken for 2 to 5 years) April 3, 2018

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Yuvafem (estradiol) for Atrophic Vaginitis: "After suffering through the defective Teva pharmaceuticals applicator, I have switched from Teva pharmaceuticals generic vagifem to Yuvafem and the Yuvafem applicator works like a charm. Thanks Yuvafem!"

   
9.0

Dina (taken for 6 months to 1 year) April 1, 2018

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Estrace Vaginal Cream (estradiol) for Atrophic Urethritis: "I used to get urinary tract infections frequently. Since I have been on the Estrace cream- none. Just wish it weren't so expensive!!"

   
10

Anonymous (taken for 6 months to 1 year) March 21, 2018

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Yuvafem (estradiol) for Atrophic Vaginitis: "Initially it was great. And on the upside it is effectively treating the vaginal atrophy. But now a year later, for the couple of days after each insert, I have discharge to the point that it feels like urinary incontinence. It's uncomfortable, and frankly it's gross. I have to wear a panty liner theres so much of it."

   
3.0

Anonymous (taken for 1 to 2 years) March 12, 2018

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Yuvafem (estradiol) for Atrophic Urethritis: "I have not noticed any performance difference between Vagifem vs. Yuvafem. However, the packaging is terrible. I need scissors to separate the applicators from each other; when received the foil often is ripped and plungers are often pushed in thus releasing the drug tablet. Since I have frequent UTIs I am NOT following advice to manually insert the tablet if it is not in the applicator. My HMO is only looking at the cost factor and it is very frustrating to be supplied with a very inferior drug product."

   
2.0

New Grandma (taken for 1 to 6 months) March 8, 2018

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For Atrophic Vaginitis: "I was switched to a vaginal tablet made by Teva. The pill does not release and is uncomfortable to use. I had used Vagifem prior to using the generic brand and never had a problem with the applicator."

   
4.0

Pjc (taken for 1 to 6 months) March 5, 2018

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For Atrophic Vaginitis: "I have found Teva brand applicators to be defective. They do not eject the tablet"

   
2.0

Lynn March 2, 2018

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For Atrophic Vaginitis: "Used vaiufem for years with no problem. Then insurance only covered this generic version for low co pay. My doc sent a do not substitute order but BC/BS still charged higher price. This drug packaging and applicator are defective. Can't open one applicator without the side by side applicator ripping. The applicator is a joke. It does not eject like vagifem did. Tried multiple times and then when I thought I got it, found the tablet floating in the bathtub the next day. Clearly, this generic replacement for vagifem is defective and I'm annoyed my insurance company felt it was a suitable generic replacement. Not sure how the price of vagifem compares to Viagra and if BC/BS requires generic for that but will be inquiring. So sad that this defective generic was approved. It's a joke and sad that the higher authority for meds has approved this."

   
1.0

Bud February 26, 2018

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