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User Reviews for Estradiol

Also known as: Estrace Vaginal Cream, Estring, Vagifem, Yuvafem

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Learn more about Estradiol.

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Condition DownUp Reviews Compare Avg. Ratings DownUp
Atrophic Vaginitis 64 reviews 50 medications
   
7.3
Atrophic Urethritis 11 reviews 45 medications
   
6.1
Summary of Estradiol reviews 75 reviews 6.7

Reviews for Estradiol

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Have been on this for four weeks. First two weeks 1 gram daily then twice per week. Just a few days after starting breasts felt full and tender like I was breastfeeding, gained up to 4 lbs. Did the trick for relations with husband. I'll be deciding if it's worth it ( physical effects and possible cancer of uterus) when I go back for a follow up visit this week."

   
10

28ST September 18, 2016

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Estring (estradiol) for Atrophic Vaginitis: "Estring makes a huge difference in my life. It restored my ability to have normal sex (win!), with no pain and with normal lubrication. I've used it for 2+ years. The first few months my weight went up 10+ lbs and I've been unable to lose weight. It is worth getting used to a new normal weight for me to feel normal again. I have a false advertising complaint against Estring. Their Coupon says in large letters, "Pay no more than $15 for your ESTRING prescription." The very fine print says. "savings are limited to $100 for each of 4 uses," meaning you only save $100 for each Rx, but this Rx is VERY expensive, so no one pays $15, but usually much more. Still some savings are better than none."

   
9.0

Everclimber (taken for 2 to 5 years) August 31, 2016

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Vagifem (estradiol) for Atrophic Vaginitis: "Really good experience with stronger dose. Now on lower dose and after a year or so the effect is nothing like as good. As atrophic vaginal conditions increase with age, it is obvious that what once worked well will no longer be effective at lower dosage. It is a shame that so many women will have to suffer this painful condition because of a shiort term study of a very small sample of women."

   
5.0

lizziep August 31, 2016

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Vagifem (estradiol) for Atrophic Vaginitis: "This med was a complete cure....I went through menopause - experienced extreme dryness and horrific pain during relations....constant urinary infections as well. I use the 10mcg and it was perfect....get it a lot cheaper through israelpharm.....different amounts in packaging - but still a heck of a lot cheaper than Walmart....yay!!!"

   
10

mama28 (taken for 1 to 6 months) August 22, 2016

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Vagifem (estradiol) for Atrophic Urethritis: "After years of suffering with recurrent cystitis, terrible pain in my urethra, bloating, chronic fatigue, I've recently been put on vagifem and the difference has been incredible. Had previously tried antibiotics, over the counter remedies, various herbal treatments - NOTHING worked. I started Vagifem during a bad attack of cystitis and within hours the pain had all but gone. I've also noticed I have more energy, and a little more zest for life! Its early days and I have slight nausea, but so far so good. I'm delighted that something has worked at last."

   
10

AmandaH24 August 19, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Urethritis: "I started using Estrace because of frequent urination with burning, and dryness. I started menopause 4 yrs ago. When I use Estrace after 2 days I have to stop due to bleeding, and cramping that lasts for a week. I'm not a fan!"

   
4.0

Cherriecee (taken for less than 1 month) August 16, 2016

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Vagifem (estradiol) for Atrophic Vaginitis: "I had been using vagifem for about 8 years and now have uterine cancer. I am having a hysterectomy next week as a result. When my cancer surgeon found out I was using vagifem tabs he immediately had me stop it."

   
4.0

S Jean (taken for 5 to 10 years) June 18, 2016

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Estring (estradiol) for Atrophic Vaginitis: "I have been suffering and nothing else has worked. So I tried this and initially no pain but then it became so painful I had to remove it immediately. I will NOT be using this again. It caused me to have to urinate a LOT and a lot of pressure. Don't waste your money or time."

   
1.0

BeeCareful June 16, 2016

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Vagifem (estradiol) for Atrophic Vaginitis: "My doctor prescribed 10 mcg vagifem,then another doctor after hearing my complaints of leg cramp and other vague problems told me to stop using it. But there is nothing out there which works for me,Premarin cream is not for me,combipatch I gave up long ago,so 10 mcg vagifem seems to be my only option. all the other non hormone lubrications do not work. So if you are taking it,watch closely for side effects,10mcg is the lowest dosage,25 mcg is not allowed by FDA in USA."

   
8.0

michelle10167 June 13, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "It has improved my sex life and also eliminated UTI. I use once or twice a week. I also use vaseline daily after each shower."

   
10

BKGG (taken for 2 to 5 years) June 6, 2016

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Estring (estradiol) for Atrophic Vaginitis: "Horrible. I would not recommend this to my enemy. I went through menopause 7 years before using this and all the while I stayed at a steady weight, no problems with weight gain. I used Estring for 3 months and gained 10 pounds. I think it did something to my hormones. Gaining weight wasn't the reason I stopped using it. I could not bear the extreme breast pain and and persistent abdominal cramps. I will never use anything like this again."

   
1.0

Anonymous (taken for 1 to 6 months) June 3, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Urethritis: "I have been using Estrace cream for 11 years and it's been working. I use about 1/3 applicator every 5 or 6 days. Suddenly, it stopped working. I don't have a bladder infection, I already went through yeast infection treatment both Diflucan and vaginal creams, and my vagina still burns. The Estrace cream relieves it, but only for about 6 or 10 hours. I am 70 and not sexually active. I know years ago the urologist said everything look kind of shriveled up and dry down there. Could the hormone cream just not work anymore? Now what do I do?"

DeDe126 April 23, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Very sexually active until severe abrupt menopausal symptoms at 55. AV symptoms the most bothersome as overnight I shrunk up, dried up, itched, burned and tore. Intercourse was out of the question. Dr. gave me a sample of Estrace Vaginal cream. I admit I was afraid to use it and had little faith that it would help so I used only a pearl size amount on clean dry skin every night for 2 weeks. That ammt. Is sufficient to cover all the external parts and more, it emulsifies. I am COMPLETELY healed as far as pain with intercourse and also pain upon urination. It was a MIRACLE for me. Side note: If you stop using it (3X a week after the initial 2wk nightly use) you'll be back at square 1. I give Estrace a 10+ rating C: A tube lasted 6 months"

   
10

Sexpert March 30, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Someone replied to my first response that I need to wait 6 months. Well its been way over 2 years now, and I am still tearing and having that stinging feeling. I use 100% organic coconut oil for a lube, as my OBGYN said to try that too. I have no side effects from the coconut oil. I used both and then after "enduring" sex, I was left with a couple of tears that were bleeding and stinging. I am going to call her back and tell her I need extra strength. Even after the 1 mg amount, bathing the walls of my vagina, its still not enough. I am only 55, and did not think, this was going to be the end of me. My husband is 13 years older than me, and I am the one that has to turn him away because I am not healed enough to try again"

   
5.0

I need extra strength! (taken for 2 to 5 years) March 19, 2016

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Estring (estradiol) for Atrophic Urethritis: "I used this for vaginal and urethral atrophy. It worked great and I would still be using it but my job changed insurance and it's not covered. There is a coupon to reduce co-pay to $15.00"

   
10

Anon65P (taken for 1 to 2 years) February 25, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "I have been taking this to see if it will help with my vaginismus, which is where the vaginal clamps down during any sort of penetration due to a trauma. I think it has helped mildly, but not cured my condition - which is not surprising, since it's mostly mental."

   
7.0

Okay Karly (taken for 1 to 6 months) February 25, 2016

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For Atrophic Urethritis: "I went straight to a specialist Dr., a Urologist, because I was having vaginal discomfort that I could not really explain or understand. I am not in menopause yet, I still have my period; however, I was feeling like I had a UTI, but I didn't have a UTI. The Dr. asked what Rx's I'm taking and when I told him Prozac, then he told me that is one of the side effects of Prozac. He warned me of the high cost, unless I went to a specific Pharmacy where it cost @ $20-$25. I have to drive 60 miles to get it, but it saves me @ $175, so, I don't mind the drive. I haven't been on it long, so, I'm not sure how well the cream is going to work."

   
4.0

Butterfly33333 February 23, 2016

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Vagifem (estradiol) for Atrophic Urethritis: "awful leg pain, vaginal burning like on fire, back pain, pounding heart, dry cough, stomach pain and diarrhea"

   
1.0

Joyce 51 February 19, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Urethritis: "My urologist has just put me on the cream 3 times a week for preventing uti's. I just started using it so not sure if it will help with this but I pray that it does because the past year I have had one UTI after another and I am tired if being on antibiotics all the time. The antibiotics are so hard on my gut. Anyways no libido and hopefully that will improve too. So far no bad side effects either so that's good. I will be. 60 in may. I always was very active sexually now I don't even want to be touched and my husband is not happy but understanding. So anyways will report back and hopefully this cream is a miracle worker!"

   
5.0

taragurl February 10, 2016

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Estring (estradiol) for Atrophic Vaginitis: "The estring worked very well for vaginal atrophy and dryness. Intercourse was no longer painful. However, I had it for three months and gained 7 lbs. during that time, (with no other changes to my diet or exercise regime), almost all of it showing up in my belly! I took it out for a few days while waiting to refill the prescription and immediately lost 2 lbs. As soon as I put the new one in, I re-gained the 2 lbs. in a matter of a few days. I'm not sure if I'm going to keep using it. I love the convenience, as I had tried Estrace cream and found it messy and a hassle to remember to use it, and the estring definitely alleviated my symptoms, but I can't stand the weight gain."

   
8.0

Dog Lady February 7, 2016

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Vagifem (estradiol) for Atrophic Vaginitis: "54 and Suffering Severe vaginal dryness took vagifem 10 m for 10 days only had to stop due to severe abdominal pain never again will I take this drug users please beware"

   
1.0

Ginney-t (taken for less than 1 month) February 4, 2016

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Vagifem (estradiol) for Atrophic Vaginitis: "I have only been taking this for a few months, but notice a big difference, I suffered really bad pain during intercourse and this has improved the situation, I also think it has levelled out my menopausal moods. I will be staying on it. I am fortunate to live in Scotland where I do not pay for this medication directly, prescriptions are free."

   
9.0

hellojoanie (taken for 1 to 6 months) February 2, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "Extraordinarily overpriced since it is plant based - which means it is probably just soy. Even with my medicare drug insurance, it was going to be over $200. I called a Pharmacy where I used to get my compounded hormones - $27 plus shipping. Suggest you do too. "

   
7.0

Miriam W (taken for less than 1 month) January 26, 2016

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Estring (estradiol) for Atrophic Vaginitis: "Initially I had stomach pains, like period pains, then I got really bad PMT. When my husband asked if I wanted a cup of tea and my reaction was an extremely agressive 'why' I realised it was time to take out the ring. I thought I might be able to do a week on and a few days off but I got very sore within 36 hours of re insertion. I also put on weight which my osteopath says I can't afford to carry. I had a hysterectomy 20 years ago and now have vaginal atrophy, there seems no other treatment but I would not go back to this ever."

   
1.0

Fed up with estring January 26, 2016

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Estrace Vaginal Cream (estradiol) for Atrophic Vaginitis: "So - I was prescribed this and was shocked when I went to the pharmacy and she said $135. Dr. never mentioned this. I said "doesn't my insurance pay anything on this?" She checked and said "It's normally $350.00" or something. I was really angry. Angry, embarassed and this whole experience is humiliating to women. Why do I think a prescription of Viagra has a co-pay of like $10?? IT'S TIME TO STOP DISCRIMINATING AGAINST WOMEN. Especially us older women!!! That is ridiculous!!! I did not buy it, I was so angry. I may.... but I doubt it. I was prescribed this with an oral progesterone -- any one have experience with these two items combined? Thanks for letting me air that - take heed, Big Pharma."

twistedK (taken for less than 1 month) January 23, 2016

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