Estradiol topical User Reviews & Ratings (Page 5)

• Gen...
• Taken for 1 to 6 months
• November 4, 2021

For Atrophic Vaginitis "I am 65 years old, and my last period was 12 years ago. I never had any real issues with menopause, one of the very lucky ones, I realize. I was prescribed Vagifem 2.5 months ago. I did the prescribed one tab daily for two weeks, then one tab twice a week. It was prescribed to address a prolapse from the rectal side of my vagina. I was hesitant because of the amount of breast cancer on my dad's side of the family (daughters of his brothers). I was also warned about breast density on the report of my last mammogram. The doctor and intern basically blew off my concerns, saying it was a very mild medication. So, since then: I have this awful yellow discharge, which I never had before; I am gaining weight and am very bloated; I now wake up at 3 a.m. with massive headaches and a pounding heart; I cry easily now. None of those things bothered me before. I've been using 5 mg melatonin for sleep most nights and always had really good sleeps until I took this stuff. I am taking myself off of this."

• Mir...
• Taken for less than 1 month
• January 26, 2016

For Atrophic Vaginitis "Extraordinarily overpriced since it is plant-based, which means it is probably just soy. Even with my Medicare drug insurance, it was going to be over $200. I called a pharmacy where I used to get my compounded hormones - $27 plus shipping. I suggest you do too."

• Rac...
• Taken for 1 to 2 years
• September 20, 2023

For Atrophic Vaginitis "I was having very bad vaginal dryness that was leading to chronic UTIs and yeast infections, pain with intercourse, pain and burning with urination... I was miserable. I tried the Estradiol creams and they were very messy. I tried Vagifem tablets and they never dissolved properly (probably because I was so dry). Then my doctor suggested Imvexxy 10 mcg. It's a small softgel, so it dissolves easily. It's not messy at all. I used it for 14 days initially, and now I use it just twice a week to maintain. It works amazingly well. I feel back to my old self again. No more pain or burning, no more UTIs or recurring yeast infections, no more pain with intercourse. It does leave a little hint of pink on my pantyliner on the days I use it (it's a pink softgel). But it's a light baby pink color (not like blood), and I know it's just from the softgel. I buy single-use, disposable vaginal applicators (small capsule size) from Amazon to insert as I don't like using my fingers."

• Les...
• Taken for less than 1 month
• February 12, 2020

For Atrophic Vaginitis "I got bad migraine headaches on this medication. Imvexxy, I was not able to work because of the headaches/nausea. I can't tolerate this medication. I was even on the lowest dose, and it's still horrible. I will go to another option that is not hormonal. This stuff is vicious. If I could give it a zero, I would."

• Tfr...
• Taken for less than 1 month
• August 6, 2017

For Atrophic Vaginitis "Painful sex for a year and a half. Was at my wits' end, finally went to the doctor and described severe pain and dryness not relieved. She prescribed this cream. Miracle drug! No more pain, dryness improving. My husband and I are thrilled! Go on their website for a coupon. Almost 300 bucks, but I only had to pay $25.00."

• Rox...
• Taken for 1 to 6 months
• December 14, 2022

For Atrophic Vaginitis "Oh my goodness! I was prescribed Vagifem for terrible urine problems, where I constantly had pressure to use my bladder. Well, my initial response was good, and it cleared up this problem really well, but the side effects were horrendous. I had severe heart palpitations and feelings of absolute panic. I was journaling when I had heart palpitations and panic attacks, and it was always a day after I used Vagifem. I stopped using them, and I got better after stopping for 3 months. My doctor told me to try half a tablet once a week. Well, I had a reaction, but my palpitations were even worse. I cannot use them, so I don’t know how to treat my atrophic vaginitis."

• Ing...
• Taken for 6 months to 1 year
• August 3, 2020

For Dyspareunia "Have used Imvexxy for over a year. Dye should NOT be in a vaginal insert. I also have had leakage - with use overnight or during the day. A year on the medication - sex is still extremely painful and atrophy has not improved per my yearly exam. Many issues with getting the pharmacy to properly bill. Now my prescription just went up by more than $11 per month. Called the Imvexxy number and they tell me I have to wait until Jan 2021 to get another discount card. This has been an extremely frustrating experience between fighting to have the discount applied each month, no improvement with the painful sex, and the leakage of the drug."

• Che...
• Taken for 1 to 6 months
• July 30, 2020

For Atrophic Vaginitis "Great medicine. I was having recurrent UTIs and vaginal infections as a part of menopause. I have been on this medication for two months and have had no issues at all. I highly recommend it for vaginal atrophy."

• Bab...
• Taken for less than 1 month
• October 11, 2019

For Atrophic Vaginitis "I take a fairly high dose of Effexor XR, and within a week of using Vagifem 10, my depression was as bad as it has ever been! It took me a day or two to realize a possible connection. My gynecologist told me to stop using it immediately."

• old...
• Taken for 1 to 6 months
• September 15, 2014

"This medicine helped my dryness greatly, and I can once again enjoy great sexual relations. However, being a migraine sufferer to begin with, this medicine has really magnified my headaches and the number I get each month. I would love to continue using it for the effectiveness, but can't be nonfunctional due to the number and severity of my migraines."

• Cut...
• July 19, 2017

For Atrophic Vaginitis "I started using the Estring ring a little over a month and a half ago. I was unsure if I really wanted to walk around for 90 days with this object in my vagina. I thought I would be able to feel it. I was so totally wrong! Finally, after having it in my possession for a month, I finally inserted it and waited for results. Menopause had caused my vagina walls to become thinner and drier. Sex with my husband was frustrating! I still wanted to be intimate, but my vagina was not cooperating! So here we are at the almost 2-month mark, and I am totally satisfied with my ring! My walls seem to have more elasticity, lubrication, and it feels like it belongs to me again! I do not feel it at all, and my husband says it does not bother him."

• gre...
• March 22, 2013

For Atrophic Vaginitis "Doc gave me samples of Estrace cream 2 weeks ago. I use 2x per week for dryness and help restore thinning vaginal lining (prolapse problems). Noticed right away more hair loss the day after I use it. I was told this would not affect me in any way and only work locally in the vagina. I can't afford to lose more hair. I'm going to watch it and try a couple more times and if I notice hair loss continues, I'll stop. I also use an all-natural menopause cream (just started last month) has estrogen and progesterone from all-natural sources. It seemed to be helping hair loss and all-around symptoms. My first time on hormone treatment after my total hysterectomy seven years ago."

• Pat...
• October 25, 2016

For Atrophic Vaginitis "This past February, I literally thought my insides were being ripped out. I expected to see them lying on the floor after sex one Monday afternoon. I was throbbing and hurting the rest of the evening and into the morning. The next day, I called my GYN and begged to be seen. She diagnosed me with this and several rips. She gave me an Estrace cream sample and a prescription along with one for the rips. I do not have medical insurance. I healed the rips with coconut oil and started the cream, 1 oz, 2 times a week. She says it is not absorbed. Well, all I know is that my hot flashes have lessened, sex is not painful, and if I don't use it like I'm supposed to, all that changes! I'm blessed to have friends in the medical field that can keep me supplied with samples."

• Fol...
• October 10, 2009

For Atrophic Vaginitis "I'm 57 and have been using Estrace cream sporadically for about a year. I've found the drug component to be pretty effective, but I just hate that greasy goop it's put in. It seems to leave a trail for days as it leaks out. I would prefer something that absorbs better."

• Tam...
• October 12, 2020

For Atrophic Vaginitis "I’m 51 and been in menopause for a few years. Imvexxy and progesterone 100 mg have helped me 100 percent! I have been taking both for 2 weeks, and intercourse is comfortable and pleasurable. I had a few headaches the first week. No other side effects. My husband and I couldn’t be happier with the results of Imvexxy. He thinks my breasts feel larger than before too. Thankful customer."

• mam...
• Taken for 1 to 6 months
• August 22, 2016

For Atrophic Vaginitis "This med was a complete cure. I went through menopause, experienced extreme dryness and horrific pain during relations, constant urinary infections as well. I use the 10mcg, and it was perfect. Get it a lot cheaper through israelpharm. Different amounts in packaging, but still a heck of a lot cheaper than Walmart. Yay!!!"

• Swe...
• Taken for 1 to 6 months
• November 5, 2020

For Atrophic Vaginitis "I just started my 3rd month of using the 10 mcg insert of Imvexxy. The dryness has been completely reversed, which in turn stopped my chronic BV. Yay!! However, I've been feeling nauseous and crampy with a mild headache for the past 6 weeks. I also seem to be experiencing more hot flashes and night sweats. I don't want to believe it's the Imvexxy causing this and the low back pain, but since nothing else has changed, and I take no other medications, I can only assume it is the Imvexxy. I am almost 60 yrs old and have been in menopause for 8 yrs or so. I keep thinking these symptoms will go away, but they actually may be worsening. I'll likely finish using the rest of this prescription but not renew it."

• Mid...
• Taken for 1 to 6 months
• June 18, 2019

For Atrophic Vaginitis "I was prescribed Imvexxy, and 1) it took too long to work 2) I had to endure additional testing because the company that created it didn’t have the foresight to think that maybe they shouldn’t make the capsule pinkish, which, when dissolved and leaked on panties, could be mistaken for spotting in a postmenopausal female. How stupid! No thanks. My Dr. prescribed the Premarin cream for me instead. I only use a tiny amount 2x a week. Worked quickly. Not messy."

• irr...
• Taken for 6 months to 1 year
• May 7, 2020

For Atrophic Vaginitis "I am so angry about this issue. Vagifem works, Yuvafem does not. Like many of the others, my insurance changed, and now Vagifem is not covered. Yuvafem was like using nothing. Everything went right back to the way it was before weeks of treatment with Vagifem (burning urination, dryness in vagina). I give up."

• Anonymous
• Taken for 1 to 6 months
• June 30, 2019

For Atrophic Vaginitis "I’ve been using this for a few months and am new to these types of products. This product gets all over your underwear even if you insert it before bed. You wake with it everywhere. I think more comes out than stays in. I’m going to ask for something else because I don’t think this really helps dryness."

• bic...
• October 7, 2011

For Hypoestrogenism "I am a 50-year-old woman who started menopause around 37. I've been prescribed this cream and did well on it, but if I stop taking it, I tend to go back to having vaginal dryness. My main concern is that I've never been bigger than a size 8 and now I can hardly fit into a 10. I think it's caused weight gain and if I stop taking it, the weight does not go away. Has anyone else experienced this?"

• DeD...
• April 23, 2016

For Atrophic Urethritis "I have been using Estrace cream for 11 years, and it's been working. I use about 1/3 applicator every 5 or 6 days. Suddenly, it stopped working. I don't have a bladder infection, I already went through yeast infection treatment, both Diflucan and vaginal creams, and my vagina still burns. The Estrace cream relieves it, but only for about 6 or 10 hours. I am 70 and not sexually active. I know years ago the urologist said everything looked kind of shriveled up and dry down there. Could the hormone cream just not work anymore? Now, what do I do?"

• Whi...
• June 22, 2019

For Atrophic Vaginitis "I have used Vagifem for years without any issues whatsoever. It worked well and caused no problems. Then my insurance switched me to Yuvafem, and it's been a nightmare. If I could give this drug a zero, I would have. Burning, redness, the feeling of having a UTI, then actually getting a UTI for the first time in 20 years, painful intercourse. The drug is completely ineffective for what it is supposed to do, and it is causing plenty of problems. When I looked at the ingredients, I see that estradiol is the same, but the carrier ingredients are different, specifically, Yuvafem uses propylene glycol. So, I could deal with the awful packaging if the drug actually worked and didn't cause so many problems, but it doesn't work and had me thinking I had some terrible infection for the last 3 weeks till my doctor and I figured out it was the Yuvafem. I will be trying out the Estring, and if I can't deal with it, I will be paying the big bucks and going back to the Vagifem."

• liz...
• August 31, 2016

For Atrophic Vaginitis "Really good experience with stronger dose. Now on lower dose and after a year or so, the effect is nothing like as good. As atrophic vaginal conditions increase with age, it is obvious that what once worked well will no longer be effective at lower dosage. It is a shame that so many women will have to suffer this painful condition because of a short term study of a very small sample of women."

• Mar...
• December 9, 2020

For Atrophic Vaginitis "Have been using Vagifem pessaries for 12 days. Experienced headaches initially, but these seem to have disappeared. I now have severe lower back pain, like period pain, which I haven’t had since my periods stopped 6 years ago. The pain is so severe I cannot bend down or lower my body. I also seem to have flu-like symptoms and am incredibly thirsty. I bought this product as I cannot have sex without great discomfort and wanted to try it out. I have informed my GP, as I wanted to be prescribed these pessaries if the outcome was good. On the plus side, my vagina is plumper and becoming moist, so lubrication is a lot better, but unfortunately, the lower back pain is intolerable. I think I may be extremely sensitive to these pessaries even though they are a low dose, 10 mcg. I will no longer continue using Vagifem as I feel very debilitated. I wish there were some kind of alternative, one that doesn’t cause severe lower back and period pain."