Estradiol topical User Reviews & Ratings (Page 4)

• LDn...
• March 7, 2017

For Atrophic Vaginitis "I was a regular user of Vagifem and was very pleased with the results. It made sex comfortable again. I saw there was a generic available and tried it to try to save some money. This product is terrible. Everything about it is ten notches below Vagifem. You can't separate the foil packages. The applicator is sharp on the end. One of my doses was empty, and I pay $15 each. The pill does not dissolve inside you. When showering the next day, I find the tablet just sitting up there undissolved. My vaginal dryness is back to where it was before beginning Vagifem. I am a 62-year-old woman with an active sex life, my insurance will no longer pay for the brand. I wish they would have more time before releasing. I hate everything about it."

• CMB...
• Taken for 1 to 6 months
• March 12, 2020

For Atrophic Vaginitis "I am 52 years old, menopausal, and I have been using Estring for about 6 months now and LOVE it. I had severe vaginal dryness and itching. I love sex, but it was painful and I would often bleed during and after. Within 2 weeks of using the Estring, all my symptoms disappeared! Such a huge relief. The ring looks giant when you take it out of the package, and you may worry about making it fit. I had no problems inserting it and couldn’t feel it. I can’t remove it myself, so I have to enlist the help of my husband. It is worth every penny. If you are on the fence - TRY IT."

• bgk...
• Taken for 5 to 10 years
• February 29, 2020

For Atrophic Vaginitis "The last 2 times when I used Estrace cream, I had bad burning and felt like I had a UTI. Out of desperation, I decided to try a vaginal yeast infection cream w/applicator to see if it made a difference. It did, both times! Within hours, the symptoms decreased. By the next day, no further issues. Had no idea others had burning from the Estrace cream until I got on this site. May check out getting it compounded. I wonder why after years of using the Estrace (brand name), did this start all of the sudden. Have the ingredients changed?"

• Bab...
• Taken for less than 1 month
• February 4, 2021

For Atrophic Vaginitis "I take antidepressants each morning, as well as several combined sleeping tablets. Within a few days of using Vagifem, I sank into deep depression, and by about 6 days, I was almost suicidal! PLEASE, if you take antidepressants (I take Efexor XR), consider carefully using this product. It is an uncommon but serious side effect for some!"

• MQB...
• November 14, 2011

For Atrophic Vaginitis "I am a 57-year-old female who started using Estrace for vaginal dryness, painful intercourse, and almost immediately noticed falling hair. I asked my doctor who assured me that it would never cause hair loss. After 3 months, my hair was so thin that a rubber band no longer stays put. I quit Estrace almost 2 months ago, and the hair continues to fall."

• Bew...
• Taken for 2 to 5 years
• January 22, 2017

For Atrophic Vaginitis "I'm only giving Estrace Cream a 3 rating on the scale due to there being issues with the product. I have been using this product for a couple of years. It did help until the last few months. I went from using it 2-3 times a week to needing it every other day. My frustration comes from the amount that is actually in the tube. It says there are 42.5 grams in the tube, I always keep track of the amount in the tube and end up with about 24 grams out of the tube in the end. Has anyone else kept track of this? Also, I can't afford it, when I went yesterday to pick up a new tube, they wanted $290 for 1 tube?! Why would it be this expensive? That was even after my insurance paid a portion."

• Anonymous
• July 14, 2009

For Atrophic Vaginitis "I'm a 41-year-old woman who went into early menopause two years ago. Vaginal dryness and all the other wonderful symptoms of menopause are not something that I would like to deal with at my age, but sometimes we can't control. So, my doctor prescribed Estrace, and I use 1mg 2x a week. I was told that it would take about 6-8 weeks before seeing a difference. At the end of that time frame, I saw only a slight difference in vaginal dryness but many side effects. I had headaches, dizziness, bloating, and calf pain."

• Jea...
• Taken for 1 to 6 months
• January 21, 2019

For Dyspareunia "I had been taking Imvexxy for almost 5 months. I had seen no positive changes. I started having heart palpitations after 3 months of usage. Then I began to notice pain from my fibroid tumors returning. I have discontinued taking this product. I’d rather have painful intercourse than live with fibroid tumors and heart palpitations. I’m wondering how many other women have had these same problems and never reported them."

• Sha...
• December 20, 2015

For Atrophic Vaginitis "Used as directed and not sure it did much, truthfully. I have been having bioidentical estrogen and testosterone implants, and that does seem to be very effective. Also, an OTC product called Luvena (Restorative Vaginal Moisturizer, pH balanced) is super effective and doesn't cause the stinging and breakthrough bleeding of Estrace. Luvena is significantly cheaper than the insanely overpriced Estrace ($300 or a $72 co-pay). Really, Estrace should cost about $15 and not the criminally high price it is. Bottom line: Not a fan of Estrace and certainly not worth the $72 co-pay for stinging and bleeding for me at ten years post-menopause."

• Rac...
• Taken for less than 1 month
• April 19, 2018

For Atrophic Vaginitis "I’ve only been on Estrace for a week, my symptoms? Hot flashes day and night, mood swings, I’d go up to the bedrooms and feel my heart palpitating, low energy, have a hard time getting up in the morning, no interest in anything. This cream is heaven-sent, I’m looking forward to the next couple of weeks, have faith that it can only get better. I feel like a human being. I was honestly feeling like I was losing who I am. I’ll keep you guys posted..."

• Gig...
• Taken for less than 1 month
• February 27, 2019

For Atrophic Vaginitis "Best decision I ever made. I had lost feelings in my breasts and was so dry down there I wanted to cry. Was in vaginal pain every day. Dr. said Estring would take at least 2 weeks to begin working. For me it began working within 3 days. I feel like a new woman."

• Sha...
• Taken for 1 to 2 years
• December 23, 2015

For Atrophic Vaginitis "Side effects of breakthrough bleeding and little relief from thin tissue do not warrant the cost. If over $300 with a co-pay of $75. This is price gouging for a cream that should cost no more than $20 at the very most -- and I'm being generous. Overpriced meds are out of control. I won't bother using Estrace anymore."

• Qan...
• Taken for less than 1 month
• August 17, 2018

For Atrophic Vaginitis "I am 57 years old and 3 weeks on low dose Vagifem 10 mcg - gained 5 kg and experienced a hypertensive crisis 200/100 blood pressure at its worst. My BP was completely normal beforehand. Spoke to GP who took me off straight away - really rare side effect but can be found in the small print. 4 days later, BP returned to normal, now 120/80. Watch your BP, girls. On the upside, had sex with minimal pain, which was fantastic, but guess what, can't take the drug. Talk about depressive!"

• Gee...
• January 18, 2019

For Atrophic Vaginitis "I had great results after a few days of taking it, but it has been 10 days now and I feel an 'itchy feel-good sensation' in my vagina. I am worried I am getting a yeast infection now. Has anyone else experienced this? I am assuming it’s not just hormones making me feel fluttery in there."

• Anonymous
• November 20, 2010

"I've been using Estrace 1 mg 2 times a week for around 9-10 years. It does help with the dryness, itching, and burning symptoms, but I've had two bladder infections. I can't help but wonder if having to REUSE the applicator (and maybe not being able to wash it properly or having leftover soap on it) is the cause. I hope to find a good source for disposable applicators so I can feel safer using this medicine."

• Sus...
• Taken for 5 to 10 years
• January 26, 2023

For Atrophic Vaginitis "I used Vagifem for atrophic vaginitis for 8 years. I experienced hair loss, weight gain, breathlessness, painful headaches, and extreme shoulder pain resulting in limited mobility in my arms. I have also developed an abnormal heart rate resulting in atrial fibrillation and high blood pressure. My doctor advised me to stop using it. On stopping, all of the above symptoms disappeared. I think this medication is highly toxic for some women and should be monitored more closely by your doctor."

• Nic...
• Taken for less than 1 month
• July 20, 2020

For Atrophic Vaginitis "Use of Vagifem to address bladder frequency has caused significant irritation, itchiness, and rawness around the vaginal area, as well as thick white discharge. I have discontinued it and am attempting to treat these symptoms, which have progressed to the urethra. Very discouraging, as many women find it very helpful for postmenopausal conditions."

• ABK...
• Taken for less than 1 month
• December 24, 2020

For Atrophic Vaginitis "My Dr. wanted me to take this every night for two weeks. I had to discontinue use after 4 nights. When I would get up in the morning, there was so much discharge. I had a horrible headache the entire four days that I took it. It made my rosacea flare up. I felt tired and run down, and my body felt sore."

• NAa...
• Taken for 6 months to 1 year
• May 11, 2019

For Atrophic Vaginitis "Yuvafem makes me spot, and it gets worse over several days. First yellow and dark brown, and then bloody discharge. My doctor checked me out. I’m fine, so it’s definitely this medication. I did not have this problem with Vagifem and will tell my doctor that Vagifem is what I want. I am 63 years old. When I use the Yuvafem, I have to wear a liner. Terrible medication and should be pulled from the market."

• dee...
• Taken for less than 1 month
• August 15, 2014

For Atrophic Urethritis "For the past 2 years I have suffered terribly with incontinence. A month ago I decided to go to the doctor and she prescribed Vagifem. It was an instantaneous result. I can even jog now without any leaking. It has changed my life. The only negative thing I find is that I gained 2kg or it can be water retention. But not having incontinence outweighs the water retention/weight gain."

• Rac...
• Taken for 1 to 2 years
• September 20, 2023

For Atrophic Vaginitis "I was having very bad vaginal dryness that was leading to chronic UTIs and yeast infections, pain with intercourse, pain and burning with urination... I was miserable. I tried the Estradiol creams and they were very messy. I tried Vagifem tablets and they never dissolved properly (probably because I was so dry). Then my doctor suggested Imvexxy 10 mcg. It's a small softgel, so it dissolves easily. It's not messy at all. I used it for 14 days initially, and now I use it just twice a week to maintain. It works amazingly well. I feel back to my old self again. No more pain or burning, no more UTIs or recurring yeast infections, no more pain with intercourse. It does leave a little hint of pink on my pantyliner on the days I use it (it's a pink softgel). But it's a light baby pink color (not like blood), and I know it's just from the softgel. I buy single-use, disposable vaginal applicators (small capsule size) from Amazon to insert as I don't like using my fingers."

• mon...
• Taken for 1 to 6 months
• March 21, 2019

For Atrophic Vaginitis "Used Imvexxy before bed the first time and could tell a difference the next morning, a HUGE improvement for me. I guess over time I hadn't realized how Sahara-dry things were. Still new to it, but haven't noticed any side effects thus far. HUGE HUGE difference."

• Jen...
• Taken for 1 to 6 months
• January 25, 2019

For Atrophic Vaginitis "I started using Estring because of vaginal dryness and urinary frequency. It's been 4 weeks since I started using the ring and found that it was a little odd inserting a ring that size. So far, I am tolerating it well. I went from being dry as the Sahara Desert to feeling moist again, so I give it an A for that. I had been on Estrace for 2 years and cannot stand the messiness. Estrace cream made me get more yeast infections. I'm done with the cream and in with the ring. Hopefully, I will still keep having good results with the ring."

• Mad...
• Taken for 6 months to 1 year
• October 27, 2019

For Atrophic Vaginitis "I was on the generic for atrophic vaginitis and bladder issues. I was on it twice a week for 10 months. Ultrasound, before I started, showed everything normal...after 10 months, numerous gallstones and hepatic hemangioma. Now I have to have my gallbladder out. It did work wonders, but I can't take it...Gyn. told me to stop immediately. I wish there were more things to help this condition!!"

• Les...
• Taken for less than 1 month
• February 12, 2020

For Atrophic Vaginitis "I got bad migraine headaches on this medication. Imvexxy, I was not able to work because of the headaches/nausea. I can't tolerate this medication. I was even on the lowest dose, and it's still horrible. I will go to another option that is not hormonal. This stuff is vicious. If I could give it a zero, I would."