Comparing Diclofenac vs Tylenol
| Diclofenac | Tylenol (acetaminophen) |
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| Diclofenac | Tylenol (acetaminophen) |
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Prescription only
Diclofenac is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs. Prescribed... View more |
Prescription and OTC
Tylenol is an effective mild pain reliever with a low risk of side effects but the potential for liver damage exists, even at recommended dosages. The risk is increased with higher dosages, a... View more |
Related suggestions Headache
Muscle Pain
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| More about Diclofenac | More about Tylenol (acetaminophen) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Diclofenac has an average rating of 7.3 out of 10 from a total of 697 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 21% reported a negative effect. |
Tylenol has an average rating of 5.9 out of 10 from a total of 31 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 35% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Diclofenac side effects |
View all Tylenol side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Diclofenac prices |
View all Tylenol prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Cambia, Cataflam, Lofena, Voltaren, Zipsor, Zorvolex | Other acetaminophen brands include: 7T Gummy ES Chewable Tablets, Abenol, Acephen, Actamin, Actimol Children's, Actimol Infant, Adprin B, Aldi Hedanol Paracetamol, Alpha First Aid Supplies Paracetamol, Alphapharm Paracetamol, Altenol, Alvedon, Amadol Paracetamol, Amcal Childrens Paracetamol 1-5 Years, Amcal Childrens Paracetamol 5-12 Years, Amcal Paracetamol Infant Drops 1 Month to 2 Years, Amcal Paracetamol Pain Relief, Amcal Paracetamol Tabsules, Aminofen, Anacin Aspirin Free, Anadin Paracetamol, API Healthcare Coloufree Childrens Paracetamol, API Healthcare Colourfree Childrens Paracetamol Double Strength, API Healthcare Paracetamol, Apra, Arthritis Pain Relief, Atasol, Atasol Forte, Aurophen, Bi-Lo Paracetamol, Biochemie Paracetamol, Blooms the Chemist Paracetamol, Bristol Pharma Paracetamol, Buckley's Complete, Bydol, Calpol Fastmelts, Calpol Infant, Calpol Paediatric, Calpol Six Plus, Capital Chemist Paracetamol, Cetafen, Cetafen Extra, Chem Mart Chemadol, Chem Mart Chemadol Children 1 to 5 Years, Chem Mart Chemadol Colourfree, Chem Mart Chemadol Colourfree Children 5-12 Years, Chem Mart Chemadol Colourfree Childrens 1-5 Years, Chemists Own Chiildrens Paracetamol 5-12 Years, Chemists Own Childrens Paracetamol 1-5 Years, Chemists Own Paracetamol, Chemists Own Paracetamol Capseals, Chemists Own Paracetamol Pain & Fever 1 Month to 2 Years, Chemists Own Paracetamol Pain & Fever 1 to 5 Years, Chemists Own Paracetamol Pain and Fever 5 to 12 Years, Chemplus Paracetamol, Chemworld Colourfree Childrens Paracetamol Double Strength 5-12 Years, Chemworld Colourfree Childrens Paracetamol Junior 1-5 Years, Chemworld Paracetamol, Chemworld Paracetamol Infant Colour Free, Children's ElixSure, Children's Silapap, Children's Tylenol, Childrens Panadol 1 - 5 Years, Childrens Panadol 1 - 5 Years Colourfree, Childrens Panadol 5 - 12 Years, Childrens Panadol 5 - 12 Years Colourfree, Cipla Genpharm Paracetamol, Claradol, Coles Paracetamol, Conacetol, Conney Aspirin-Free, ConRx Extra Strength, Country Chemists Paracetamol, Cuprofen for Children, Dafalgan, Dakota Paracetamol, DG Health Pain Reliever, Disprol Paracetamol, Disprol Soluble Paracetamol, Doliprane, Doliprane Adultes, Doliprane Sans Sucre, Dolitabs, Dolko, Dolko Enfants, Dolono, Dolono Infant, Dolotec, Duatrol SR, Dymadon, Ed-APAP, Efferalgan, Efferalgan Pediatrique, Efferalganodis, Elixsure Fever/Pain, Equaline Pain Relief, Expandox, Fawns & McAllan Paracetamol, Febridol, Febridol Clear Effervescent, Febridol Infant Drops, Febridol Syrup for Children, Febrol Solution, Fennings Childrens Cooling, Feverall, Flu Strength Hot Lemon Powders, Galpamol, Geluprane, Genapap, Genapap Extra Strength, Genebs, Gold Cross Paracetamol, Guardian Childrens Paracetamol, Guardian Childrens Paracetamol 5-12 Years, Guardian Paracetamol, Guardian Paracetamol Tabsules, Help I Have A Headache, Home Brand Paracetamol, HyVee Health 8 Hour Pain Relief, Infant's Tylenol, Infantaire Drops, Jr. Tylenol, Leader 8 Hour Pain Reliever, Lemsip Childrens Cold & Flu, Lemsip Cold and Flu Liquid Capsule, Lemsip Headcold, Lemsip Max, Lemsip Original, Lemsip Pharmacy Non-Decongestant Formula, M-Pap, Mapap, Mapap Arthritis Pain, Mapap Extra Strength Rapid Burst, Mapap Rapid Release Gelcaps, Mapap Rapid Tabs, Masophen, Midol Long Lasting Relief, Nortemp Children's, Orajel Maximum Strength Toothache, Panadol, Panadol ActiFast, Panadol Childrens, Panadol Colourfree Drops, Panadol Extend, Panadol Gel Caps, Panadol Gel Tabs, Panadol Jr, Panadol Mini Caps, Panadol Osteo, Panadol Rapid Handipak, Panadol Soluble, Panamax, Panamax 240, Panamol, Paracetamol, PediaCare Children's Acetaminophen Fever Reducer/Pain Reliever, PediaCare Infants' Acetaminophen Fever Reducer/Pain Reliever, PediaCare Smooth Melts Acetaminophen Fever Reducer/Pain Reliever, Pharbetol, Silapap Childrens, Tactinal, Tempra Quicklets, Topcare 8 Hour Pain Relief, Topcare Arthritis Pain Relief, Triaminic Fever Reducer Pain Reliever, Triaminic Infant Drops, Tycolene, Tylenol 8 Hour, Tylenol Arthritis Pain, Tylenol Childrens Paracetamol, Tylenol Cold Sore Throat, Tylenol Cool Caplet Extra Strength, Tylenol Extra Strength, Tylenol Regular Strength, Tylenol Sore Throat Daytime, Tylophen, UN-Aspirin Extra Strength, Valorin, Vicks Formula 44 Custom Care Body Aches, Vitapap, Zee Unaspirin ES View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1.8 hours |
2.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 446 drugs are known to interact with Diclofenac:
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A total of 160 drugs are known to interact with Tylenol:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 28, 1988 |
June 08, 1994 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
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N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.