Comparing Diclofenac vs Lyrica
| Diclofenac | Lyrica (pregabalin) |
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| Diclofenac | Lyrica (pregabalin) |
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Prescription only
Diclofenac is an effective medicine for relieving pain but may be associated with an increased risk of cardiovascular and gastrointestinal side effects compared with some other NSAIDs. Prescribed... View more |
Prescription only
Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. Prescribed for Neuropathic Pain, Neuralgia, Fibromyalgia, Diabetic Peripheral Neuropathy, Postherpetic... View more |
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| More about Diclofenac | More about Lyrica (pregabalin) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Diclofenac has an average rating of 7.3 out of 10 from a total of 695 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 21% reported a negative effect. |
Lyrica has an average rating of 6.4 out of 10 from a total of 927 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 26% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Diclofenac side effects |
View all Lyrica side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Diclofenac prices |
View all Lyrica prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Cambia, Cataflam, Lofena, Voltaren, Xiclo, Zipsor, Zorvolex | Other pregabalin brands include: Lyrica CR | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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1.8 hours |
6.3 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 444 drugs are known to interact with Diclofenac:
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A total of 286 drugs are known to interact with Lyrica:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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July 28, 1988 |
December 30, 2004 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.