Dantrolene Alternatives Compared
| Dantrolene | Baclofen | Botox |
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| Dantrolene | Baclofen | Botox (onabotulinumtoxinA) |
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Prescription only
Prescribed for Malignant Hyperthermia, Chronic Spasticity. dantrolene may also be used for purposes not listed in this medication guide. |
Prescription only
Baclofen relieves muscle spasms associated with multiple sclerosis and spinal cord injury or disease, but its use is limited by its ability to cause sedation and increase seizure risk. Prescribed for... View more |
Prescription only
Botox is approved to treat many conditions, such as chronic migraine, involuntary muscle contractions or twitching, excessive sweating, increased saliva, and overactive bladder to name a few. Botox... View more |
Related suggestions Chronic Spasticity
Popular comparisons
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| More about Dantrolene | More about Baclofen | More about Botox (onabotulinumtoxinA) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Dantrolene has an average rating of 7.0 out of 10 from a total of 4 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 33% reported a negative effect. |
Baclofen has an average rating of 6.9 out of 10 from a total of 419 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. |
Botox has an average rating of 5.5 out of 10 from a total of 443 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 44% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include:
See also: dantrolene side effects in more detail. |
Commonly reported side effects include:
See also: baclofen side effects in more detail. |
Common side effects include:
See also: Botox side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all dantrolene prices |
View all baclofen prices |
View all Botox prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Dantrium, Dantrium Intravenous, Revonto, Ryanodex | Fleqsuvy, Gablofen, Lioresal, Lioresal Intrathecal, Lyvispah, Ozobax | Other onabotulinumtoxinA brands include: Botox Cosmetic | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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8.7 hours |
6.8 hours |
N/A |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 292 drugs are known to interact with dantrolene:
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A total of 358 drugs are known to interact with baclofen:
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A total of 114 drugs are known to interact with Botox:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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February 18, 2016 |
November 28, 2017 |
December 09, 1991 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.