Comparing Acetaminophen / Codeine vs Naproxen
| Acetaminophen / codeine | Naproxen |
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| Acetaminophen / codeine | Naproxen |
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Prescription only
Acetaminophen/codeine may be used to treat mild-to-moderate pain that is unrelieved by nonopioid analgesics. However, the codeine component of this combination medicine is addictive and may cause... View more |
Prescription and OTC
Naproxen is used to relieve pain and inflammation associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendonitis, bursitis... View more |
Related suggestions Osteoarthritis
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| More about Acetaminophen / codeine | More about Naproxen | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Acetaminophen / codeine has an average rating of 4.8 out of 10 from a total of 231 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 47% reported a negative effect. |
Naproxen has an average rating of 6.8 out of 10 from a total of 683 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 25% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Acetaminophen / codeine side effects |
View all Naproxen side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Acetaminophen / codeine prices |
View all Naproxen prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Aflaxen, Aleve, Aleve Back and Muscle Pain, All Day Pain Relief, All Day Relief, Anaprox-DS, Comfort Pac with Naproxen, EC-Naprosyn, Flanax Pain Reliever, Midol Extended Relief, Naprelan, Naprosyn, Naproxen Sodium DS, Pamprin All Day Relief View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3.5 hours |
18 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Multiple
The drug has multiple schedules. The schedule may depend on the exact dosage form or strength of the medication. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 616 drugs are known to interact with Acetaminophen / codeine:
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A total of 474 drugs are known to interact with Naproxen:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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May 31, 1974 |
March 11, 1976 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.