Semaglutide and Vomiting: What Users Say (Page 4)

• deb...
• Taken for less than 1 month
• February 13, 2019

Semaglutide for Type 2 Diabetes "I started taking the .25 a week ago. The first 2-3 days, I had stomach pain, headache, and vomiting, none of which were bad. I took my second shot yesterday, and the gas was awful. The one thing that I really wanted to do was to lose some weight, and so far, I've lost 3 lbs. My appetite is slowly fading, but I have to watch myself because I'm still craving sweets at night. I have to make myself drink fluids, but luckily the one thing I did crave was Cokes, and I don't even think about them anymore. I love this med."

• Thi...
• June 27, 2018

Semaglutide for Type 2 Diabetes "I've been taking this for 2.5 months. I've lost a solid 10 pounds. I take it right before bed so I can sleep off the initial side effects, if any. There is a little bit of diarrhea, nothing too crazy. I have major loss of appetite, I can eat half meals or half kids' meals and I'm always full after a few bites. Sugars are low. The major side effect is nausea, but it isn't every day. I've thrown up 3 times within the past 3 months, which is something I never did prior. It comes out of nowhere, and honestly, I'm unsure if it is this injectable or just from taking an iron supplement and vitamin. Could be the vitamin. I feel tired also, not sure if it's just work or a side effect. Overall, I'm happy with the injectable, plus it beats taking a pill every day."

• Ano...
• Taken for 1 to 6 months
• August 18, 2025

Semaglutide for Cardiovascular Risk Reduction "Great results, lost 25 lbs in 1 month. Nausea and vomiting, side effects, also some fatigue. Problem is I vomit my other medications."

• Ano...
• Taken for 1 to 6 months
• July 24, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "I have used Wegovy for 3 months now. I'm a child, I'm 14, and there have been times that I threw up everything. After 3 months, I have lost 10 to 9 kilos."

• Ano...
• July 7, 2025

Semaglutide for Type 2 Diabetes "I am not sure if it has been very much help, as my sugar levels have been running high and would need to have my A1C checked to see if it has lowered from my last visit. Have not experienced side effects like others: headache, stomach cramps, vomiting, or excessive diarrhea. Only experienced slight stomach cramps and diarrhea when I consumed greasy foods."

• Ano...
• Taken for 6 months to 1 year
• May 17, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "It definitely works. I have lost 15% of my weight in 8 months - almost all of it since January 2025. The side effects are really bad for me though. Stomach pain, vomiting for two days after an injection, and general nausea. I may have to stop or go down to 1%."

• Jul...
• Taken for less than 1 month
• February 26, 2025

Semaglutide "I began taking this medication off-label for weight loss. I am on my second week and took my second shot last night. I felt my appetite decrease the first week. I threw up from nausea this morning. I think I ate too much yesterday. The med does slow down digestion to leave you feeling full longer. I did eat a normal serving of dinner but had eaten a couple of hours prior, and I just don't think my body could process all the food. I won't be giving up on the med. So far, the nausea/vomiting and perhaps some vision changes are the side effects I am noticing. My eyes seem tired, and it's not that I can't see, but they feel a bit strained. I should add that so far, I have lost 5 pounds in 7 days."

• The...
• Taken for 6 months to 1 year
• November 3, 2024

Semaglutide for Weight Loss (Obesity/Overweight) "I used Wegovy for several months with no problem and much success; I lost 20 lbs. For whatever reason-insurance, doctor, pharmacy, manufacturer-I was unable to take the drug. I restarted Wegovy yesterday at the same high dose I was taking when I stopped; suddenly, I threw up everything I had eaten. Today, I feel blah."

• boo...
• Taken for 1 to 6 months
• October 6, 2024

Semaglutide for Type 2 Diabetes "I started 3 months ago because my glucose levels would not change and come down no matter what I did. I tried different diabetes tablets and alogliptons, so I started on 3 mg for 1 month, no problems. Then a month on 7 mg, sugars started to drop, and I started losing a bit of weight. Now I just started 14 mg, it stops me from eating much at all, very small amounts, and I have to stop. It takes 4 goes to get a small Sunday dinner down. My glucose is right down now, which is great as the next step was injection insulin instead. I take them when I get up, 30 minutes before food as directed. But I am having bouts of vomiting. I have to run to the toilet. It can be quickly after food or a few hours after. It's early days yet, hoping it will settle as I am definitely shrinking my stomach, which is good to keep weight off. I have lost 4 lb so far, I only need a stone and a half off and hope I go back to not being diabetic. The doctor will put me back on 7 mg if I'm still sick."

• Pol...
• Taken for less than 1 month
• September 28, 2023

Semaglutide for Type 2 Diabetes "This is my first week (5 days in) and the dosage is 0.25 mg. Extreme nausea and occasional vomiting for three days, then abrupt cessation of those symptoms. Still have an appetite with occasional craving for sugar but much diminished. No weight loss yet, but I am trying to be patient. I am a nurse practitioner and expected that it would be easy to administer. I am embarrassed to say that I had a difficult time with the instructions, but I finally was successful. The instructions and the device itself were far too complicated, I thought. It was not intuitive at all. But, I am hopeful for success at both blood sugar management as well as weight loss. Thank you."

• Sue...
• Taken for less than 1 month
• June 1, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I need help to decide if Ozempic is good for me. The side effects scare me: nausea, vomiting, constipation, and exhaustion. Yikes! I really need the weight loss, though. I really want to try it. I'm curious if insurance will cover it."

• Dan...
• Taken for 2 to 5 years
• May 29, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "Got up to 2 mg after 2 years at 1 mg. Stopped because I began vomiting and feeling nauseous. Dosing 2 mg is difficult as a needle change is required."

• D W...
• Taken for 1 to 6 months
• May 22, 2023

Semaglutide for Type 2 Diabetes "I started on 0.25 mg for 4 weeks and then increased it to 5.0 mg in the fifth week as per my doctor's instructions. However, during this time, I began to experience persistent pain on my right side, which worsened to the point where I couldn't sleep on that side anymore. By the sixth week, I started vomiting. Concerned about these symptoms, I had some lab work done, which revealed that the enzymes in my pancreas were elevated at 163, whereas the normal range is 110 and below. After discontinuing the medication, within about a week, the pain subsided, and my enzyme levels returned to normal."

• Cin...
• Taken for 1 to 6 months
• May 3, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I have been taking it for over a month. No side effects for the first 2 weeks on the lower dose. Since I am using the higher dose now - I have had some very bad nausea, vomiting, and diarrhea. Also, lots of burping, and it smells terrible. When I have vomited - it is so much volume. More than any time in my life. It has reduced my appetite, but if I drink alcohol, it usually makes me physically sick."

• Tom...
• Taken for 6 months to 1 year
• April 13, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "Started Wegovy in March 2022 with a goal of losing 50-75 pounds. I ended up losing a total of 85 pounds in about 11 months. I felt great upon taking the Wegovy. Only had mild headaches and mild stomach discomfort. I was not tired, I actually felt energized. However, by December, the nausea had reared its ugly head. I took Zofran, and it helped. I was able to stick it out with the nausea until February, at which time I stopped taking it. I could no longer live with the nausea. Since I stopped taking it, I have continued to suffer nausea, vomiting, and stomach pain. My doctor and I are still trying to find the source of this continuing issue. I love the weight loss, and I love Wegovy!"

• Jas...
• Taken for 1 to 6 months
• March 15, 2023

Semaglutide for Type 2 Diabetes "It has helped me immensely! I was on 16 units of Novolog twice a day and 26 units of Levemir twice a day, and now only 10 units of Levemir a day. I lost 45 lbs, which has been amazing! But starting 2 weeks ago, I started getting really, really sick the day after the shot, flu-like symptoms, vomiting, and diarrhea at the same time for 12 days. As a diabetic, it's really bad when it lasts that long, my blood sugar was down to 30, and I couldn't eat or drink to get it back up. Glucose gel kept me alive! Finally, after 12 days, I thought I was through it and hadn't figured out that it was Ozempic, so I took my next shot. And within hours, back on the toilet and in the same boat, horrible! I have been on Ozempic for a couple of months before this reaction. It has so many good things, so I hope for you this doesn't happen, good luck!"

• Tra...
• Taken for less than 1 month
• November 23, 2022

Semaglutide for Type 2 Diabetes "I found that my sugar levels definitely saw improvement! 100% in target range! However, I suffered vomiting for about 48 hours after the first 3 doses. I’m hoping that it will subside with time, and I plan on discussing with my doctor next visit. I wasn’t able to keep water down, so dehydration is a concern."

• Suz...
• Taken for 1 to 6 months
• June 20, 2022

Semaglutide for Cardiovascular Risk Reduction "I started Ozempic in January 2022. Began with the standard .25 for 4 weeks, then .50 for an additional 4. When I injected the 1 mg, I was sick constantly. Vomiting, fatigue, and horrible heartburn. I had to stop for several weeks as I was completely worn out. I started again with the .25 and am now on the .50, but I'm noticing I am much more hungry than I was the first time around. I was wondering if any of you have injected .75 and if you found it to be helpful? I am afraid to try the 1 mg again as sick as it made me."

• For...
• Taken for 6 months to 1 year
• May 17, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "I started Wegovy in December 2021 at 281 lbs, and as of May 2022, I am weighing in at 246 lbs (35 lbs lost). I am on the full maintenance dose at 2.4 mg. I didn't notice many symptoms early on; however, as I got to the 1.7 & 2.4 mg, my side effect symptoms greatly increased - including vomiting, nausea, diarrhea, and a nasty burnt popcorn taste in my mouth. This medication will definitely cause you to lose weight as it completely takes away your appetite, but the combination of side effects, mostly the vomiting, makes me question if I will stay on this medication much longer. For reference, I take my medication on Saturday evening and suffer the side effects until about Thursday morning. From Sun-Wed, I find myself in/out of the bathroom throwing up when I attempt to eat the most basic of foods. I used to have a large passion for food, but I can't imagine eating some of my favorite things while these side effects take over. I would recommend for those suffering to lose weight with caution."

• Lou...
• Taken for less than 1 month
• May 11, 2022

Semaglutide for Type 2 Diabetes "I've been on this now for nearly 2 weeks. To help reduce blood glucose levels and boost my weight loss. I've lost 1 lb and have a loss of appetite, also nauseous most mornings if I don't eat after 30 mins of taking meds. Today I ate 2 biscuits with a cup of tea and vomited really bad, which I'm sure is related to this medication. As I feel absolutely fine now. Seems the side effects are the same as the majority here. I'll stick it out and increase the dose in 2 weeks."

• Wil...
• Taken for 1 to 6 months
• December 1, 2021

Semaglutide for Type 2 Diabetes "Week 13 using Ozempic. I am currently taking 1 mg weekly, it is week 5 on the full dose. I am thankful that it has helped get my blood sugars back to the proper range. Prior to taking it, my sugars had been out of control for about a year. I feel like a fog has been lifted, and I can actually do more than work or sleep. I do have to admit the GI issues and migraine headaches have been horrible, some weeks more than others. I also have lost about 20 pounds and am not swollen up with water retention. Thankfully, my doctor prescribed a strong anti-nausea pill, which helps with the vomiting. I am glad to have my life back, but hopefully, I can work harder to handle my diabetes naturally as soon as possible."

• Coo...
• Taken for 1 to 6 months
• September 10, 2021

Semaglutide for Type 2 Diabetes "I started taking it in July 2021. I'm up to 0.05 mg. Like mostly everyone else, I suffered from bloating, especially feeling full, not being able to consume much food. If so, you want to vomit. Not too sure how much weight I've lost yet. I can say my clothes are loose. Others have noticed I've lost a lot of weight."

• Anonymous
• Taken for 1 to 6 months
• August 25, 2021

Semaglutide for Cardiovascular Risk Reduction "I have lost 20 lbs, but have severe nausea/vomiting and constipation. Zofran and laxatives do help, but I was wondering if anyone could tell me what kind of diet would be most helpful for me."

• Alf...
• Taken for 1 to 6 months
• February 5, 2020

For Type 2 Diabetes "I have been on this weekly injection for four months and initially felt rough-vomiting, loose bowel movement, abdominal pain, but this did settle. I have been able to reduce metformin dose, HbA1c is very good and have lost 15 kilos in weight. It definitely suppressed my appetite, so smaller portions and no snacking as I did not feel hungry. I am hoping the weight loss continues as my BMI is still over 30."

• Ann...
• Taken for 6 months to 1 year
• September 9, 2019

Semaglutide for Type 2 Diabetes "Have been on Ozempic for 10 months. The first 3 months were very difficult with strong side effects. Mainly constant, but low level, nausea, occasional vomiting, and diarrhea (especially two days after the injection). However around month 3 the nausea and diarrhea subsided greatly and my appetite returned. I had lost weight very quickly (42 lbs in 3 months due to not really eating much). Had to take supplements for a while but am now eating well. The rapid weight loss led to telogen effluvium, a temporary hair loss condition. (I shed A LOT but never showed any baldness or anything). Currently, my weight is still down (I was taken off my blood pressure medication!), my blood counts are perfect, my hair is getting thick, and I eat normally. I now experience virtually no side effects. Really, really, glad I stuck out the side effects at the beginning."