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Semaglutide and Headaches: What Users Say (Page 5)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • Jun...
  • Taken for less than 1 month
  • March 13, 2021

Semaglutide for Type 2 Diabetes "I took Ozempic for the first time today around noon. I had a headache about 19 minutes after taking 0.25 mg. About an hour later, I developed red welts and a red, itchy, burning rash down the inside of my right thigh! I thought it would go away eventually, it’s been 9 hours, still there. The headache is gone, no stomach problems. However, my numbers have been around the low 109's to the low 200's after a meal. After eating soup for lunch, my glucose level shot up to 378! Has anyone else experienced this? I hope I’m able to tolerate this drug."

5 / 10
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  • Dim...
  • April 7, 2020

Semaglutide for Type 2 Diabetes "Been using Ozempic for 7 weeks, lost 12 pounds. I also take Xigduo and Lantus at night. Gas, nausea, headache, and a few low A1c. But my number is down from 8.1 to 5.4. For the gas, I find that Gas-X helps. And for the nausea, I sip on cold water and keep my meals small. I haven't thrown up yet and no constipation or diarrhea."

5 / 10
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  • Val...
  • Taken for less than 1 month
  • February 14, 2020

Semaglutide for Type 2 Diabetes "I’m a nurse. I started this med and unfortunately the nausea, gastritis, dizziness, and headache continuing into week 4 is simply not worth it. I can’t lay in bed and be miserable, which is what this does to me. At first, I actually thought I had a GI Bug. If there is any other choice, do not put yourself through this."

5 / 10
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79 Report

Frequently asked questions

  • Ice...
  • Taken for less than 1 month
  • November 4, 2019

Semaglutide for Type 2 Diabetes "OMG ... it’s not me. Dr. started me at .5 of Ozempic, first day after injection pretty much okay, then came nausea, stomach ache, headaches, then just dulled, gassy (didn’t know the burps were part of it but that increased), diarrhea, feeling beyond blah. I went to work and struggled through the day for 4 days like this. The first week wasn’t sure if it was the shot or some food, so I tried the Ozempic again. The second week was a little better, so I decided I’ll try the smaller dose. Today is day 2, but this morn, there’s the nausea, stomach ache, a little bit of headache, but lesser amounts. Despite the thought of weight loss, might be heading back to Januvia (Farxiga got the yeast infection, but it was cheap, $15 for 90 with insurance)."

5 / 10
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  • JLa...
  • Taken for 1 to 6 months
  • May 3, 2019

Semaglutide for Type 2 Diabetes "I've been on Ozempic 0.25 for five weeks, it's great for losing weight, but the side effects are not worth it. Let me review what Ozempic has been like. The first three weeks were okay, and then I started noticing nausea, stomach burning, headache, dizziness, upper back pain, severe constipation, and feeling very tired and depressed. I ended up in the ER with a mild pancreatic attack and high lipase levels. I've had no desire to eat or even drink water. It makes me gag, and I used to drink a lot of water. I'm done with these injections. I will stay on my metformin, but I can do better on a healthy eating lifestyle than on Ozempic and all the negative side effects. Quality of life has gone from a 10 to a 1, and that is not me. I'm taking my life back. It's really just healthy eating, and we can all do that with willpower. Good luck to everyone else."

5 / 10
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  • Hoo...
  • May 17, 2018

Semaglutide for Type 2 Diabetes "Initially began Ozempic 0.25mg for 4 weeks. Side effects were tiredness, constipation. My fasting blood sugar numbers were lower in the morning. When I began the 0.50mg dose at 5 weeks, I had nausea, dizziness, and lethargy the day following the first dose. The second day following that dose, I felt about 70% better. With the second dose of 0.50mg, side effects were less severe, some minor nausea, headaches, and the tiredness continued. I hope that these side effects disappear. I plan to take this medication until I get my 3-month labs, and I expect that my A1c will be down significantly. It was at 5.9 in July of 2017. Due to the stress of caring for a dying relative from September through December, it jumped to 9.3. At my next appointment, my doctor suggested I try Ozempic in combination with Metformin 500mg twice a day. I received a 3-month discount card and have not yet checked with my health insurance provider to see if it will be covered. I am an active 61-year-old female, but type 2 diabetes does run in my mother’s family."

5 / 10
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  • Vic...
  • Taken for less than 1 month
  • December 9, 2024

Semaglutide for Type 2 Diabetes "I have been taking .25, and I am suffering nausea, headache, and bloating. I thought it would be better after the first 2 weeks, but it's worse. I think I will have to stop taking it. I have not seen any benefits."

4 / 10
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More FAQ

  • lee...
  • Taken for less than 1 month
  • May 4, 2023

For Type 2 Diabetes "On my second week of semaglutide for my diabetes and have had severe abdominal and back pain, waves of nausea, headaches, bloating, and heartburn, not really sure it's worth taking it, especially when I don't really understand why it's been released to the public due to the risk of cancers like pancreatic cancer, especially as I'm a diabetic and already at risk of it. But I am going to a diabetic educator and will be getting the latest and safest medicines and advice, so if I'm told to stop it, I will... but I am persevering with it at the moment. It's a pity though, as I have heard it does work to control diabetes, and as I'm older now and in need of ridding myself before it's too late. I feel I must, but it has been dreadful so far with these side effects and especially at work. Hopefully it all works out or I will have to stop taking it... it's also hard when I'm supposed to stay on it, but it's in limited supply."

4 / 10
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  • Mar...
  • Taken for less than 1 month
  • March 26, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "Just started 2 days ago and am afraid to continue. Flu-like, headache, depression, and anxiety ramped up. Feel foggy and not wanting to get out of bed."

4 / 10
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  • Pri...
  • Taken for less than 1 month
  • May 20, 2022

Semaglutide for Type 2 Diabetes "My doctor put me on this because I was pre-diabetic, and he said I was insulin resistant. Since I’ve been taking it, I’m not as hungry, but my head hurts, and I always feel dehydrated, and so I’m peeing all day. I feel short of breath, and my chest has been feeling pains. I’m also experiencing constipation and constant light-headedness, and I’ve only been on it for 2 weeks. I may give it another 2 weeks, but not sure if the side effects are worth all this. I feel no energy, and my legs are always sore, and I’m so tired all the time. My way of living has suffered because I’m too tired to do anything and feel yuck all the time. Trying not to be frustrated because if this doesn’t help me, he wants to put me on Jardiance, but I hear so many horror stories about that one. This one isn’t as great as everyone said it would be, so who knows, maybe Jardiance will be better for me."

4 / 10
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  • Jam...
  • Taken for 1 to 6 months
  • February 2, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "I’ve been on Wegovy (Ozempic) for 10 weeks, first at 0.25 mg and now on 0.5 mg. I have not lost any weight (but not gained any). It has not curbed my appetite, and I still crave sweet stuff. I have had a few side effects, but the worst is constipation, and I have not had a normal poo since I started. I also have a headache, get dizzy if I stand up quickly, and my hair is falling out somewhat. I eat high fiber and take psyllium husk, and still no poo in a week sometimes. I would stay on it at higher doses, but the cost of £155 per month is not worth it if no effect so far. Disappointed because so many have a good result with this medication."

4 / 10
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  • kit...
  • Taken for less than 1 month
  • August 2, 2021

Semaglutide for Type 2 Diabetes "Rybelsus made me really sick. I didn't realize it until a couple of days ago. I thought I had a virus. I was practically leaning on the wall every day, trying to pull myself out of work to the car. Last week, I spent a lunch time lying on my office floor and then just left early. It is more than the nausea, it was fatigue, significant dehydration, confusion, dizziness, headaches... I'm still feeling sick after 2 days of not taking it. I just read that it can take a couple of weeks to get out of your system."

4 / 10
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20 Report
  • Kom...
  • Taken for less than 1 month
  • November 27, 2019

Semaglutide "Oh boy. I just started Ozempic for weight loss at .25. After my first injection, I was fine for two days, and then was constipated for two days—and since then I’ve been pretty darn sick. Violent diarrhea, headaches, some nausea, and very low energy. I’ve taken several days off from work as I’ve felt so bad. I’ve lost weight since I have no appetite, and nausea follows whenever I eat—even broth and crackers. I have international travel planned in 10 days, and I hope that I’m recovered by then. I may try again after my travels, but this has been rough. The worst side effects I’ve had from a new medication."

4 / 10
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  • Iri...
  • Taken for 1 to 6 months
  • October 10, 2019

Semaglutide for Type 2 Diabetes "Started Ozempic a month ago. I had a bit of diarrhea with the first two injections. Now it is just the headache and fatigue feeling. I haven't noticed any changes in appetite. I had been losing weight for three months prior to starting Ozempic. I was down 42 pounds, since starting, I'm up six pounds. I haven't noticed any difference in my blood sugar numbers. Not impressed so far."

4 / 10
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10 Report
  • Mar...
  • Taken for less than 1 month
  • August 21, 2019

Semaglutide for Type 2 Diabetes "I took my first dose a week ago. I began to have a reaction the next day. It started with a mild headache, a little nausea. Then, as the week progressed, I began to be super lethargic, tired, taking day naps. Fast forward to Sunday, I am literally near passing out at a wedding. This is not for me. I will continue to watch my calories and stay on my regular regimen. I have been ill for 4 days and can't wait for this to be over."

4 / 10
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22 Report
  • Ste...
  • Taken for 1 to 6 months
  • July 12, 2019

Semaglutide for Type 2 Diabetes "Run away. Just run away from Ozempic. Yeah, this will help with your blood sugar, sure. It will also give you terrible side effects. I have been nauseous for 2 weeks, dizzy, headache, lethargy, have gas constantly. My guts hurt so much I've cried. I ended up at the emergency room in the middle of the night, it got so severe. They gave me 2 different types of IV medicine to help and a bag of saline. They told me to quit the medicine immediately but also warned me these side effects could last WEEKS after my last dose. Can't even function. If I take the meds to keep from puking, I'm basically comatose, if I don't, my stomach, neck, and head hurt so much I cry."

4 / 10
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  • Lka...
  • Taken for 1 to 6 months
  • January 21, 2019

Semaglutide for Type 2 Diabetes "I started on this drug 4 weeks ago. First 2 weeks at 0.25, a little bit of headache and appetite totally gone. Second 2 weeks I went to 0.5, and that's when I felt bad. Bad headaches, double vision, dizzy, and I feel like I have the flu. The upside is that I lost weight, but it's not worth the side effects... I am going back to Saxenda despite the price."

4 / 10
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  • Lyn...
  • Taken for less than 1 month
  • May 10, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I haven't noticed much weight loss with this medication. I have experienced extreme nausea to almost vomiting. I have also suffered from daily headaches from this medication. I have also noticed my blood pressure fluctuates higher than my normal high. I am only on the 1.0 mg dosage right now, and my doctor will increase it next week. I do have to say the pens are very easy to use, and the needle injections don't hurt."

3 / 10
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  • dot...
  • Taken for less than 1 month
  • April 10, 2023

Semaglutide for Type 2 Diabetes "Wow, after one shot, I am sicker than a dog. I had vomited all day, had headaches, and had a $200 wasted co-pay. I'm done with this. Hope I get better."

3 / 10
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  • Tor...
  • Taken for 6 months to 1 year
  • December 11, 2022

Semaglutide for Type 2 Diabetes "Since starting, I have been constantly constipated and have a nagging headache. I have found that cravings have increased substantially. I have gained about 10 pounds as well. I am on 1 mg a week and have been using it for about 8 months. My A1C has gone down, though I think that is more willpower fighting the cravings."

3 / 10
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  • Dix...
  • Taken for less than 1 month
  • June 11, 2022

Semaglutide for Cardiovascular Risk Reduction "Two days after my first injection, I had horrible sulfur burps that were making me feel sick. By that evening, I had horrific stomach cramps; by 11:30 pm, I had uncontrollable diarrhea! My prescriber advised me to eat six small meals a day and that the symptoms would improve with each injection. I left it twelve days before my next one (as I had a couple of social things I didn’t want to miss if it happened again) and thought at first it was better. A headache day one, nausea on day two, but sulfur burps again by day three. I got indigestion medicine, but it didn’t even touch it. That night, same again; cramps, diarrhea, more burps, and this time intense nausea too. I decided at that point it might not be for me! I really hope it helps some people lose weight, but don’t expect a quick easy fix! I actually felt fatter the whole time I was on it as I was so bloated and tender."

3 / 10
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  • Jul...
  • Taken for 1 to 6 months
  • March 10, 2022

Semaglutide for Type 2 Diabetes "Newly diagnosed with type 2, started with .25 for 5 weeks. Lots of waves of nausea, headaches, and overall discomfort. Week 5 did get better, the side effects lasted just a day or two after injection. .5 has been a 2-week nightmare. Extremely painful headaches, nausea, and now constipation. I am hoping there's a different med I can try that isn't so hard."

3 / 10
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3 Report
  • Jul...
  • Taken for 1 to 6 months
  • March 10, 2022

Semaglutide for Type 2 Diabetes "Newly diagnosed with type 2, started with .25 for 5 weeks. Lots of waves of nausea, headaches, and overall discomfort. Week 5 did get better, the side effects lasted just a day or two after injection. .5 has been a 2-week nightmare. Extremely painful headaches, nausea, and now constipation. I am hoping there's a different med I can try that isn't so hard."

3 / 10
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  • Ann...
  • Taken for 1 to 6 months
  • November 11, 2019

Semaglutide for Type 2 Diabetes "Doctor suggested switching to Ozempic after weight loss plateaued with Victoza. Ozempic caused an instant headache lasting several days and nausea. Very noticeable as I never have headaches. The real problem was that two days after taking the shot, I would throw up and be too nauseous to get out of bed for about 12 hours. For the first two weeks, I thought it was food poisoning, but the vomiting was nothing like that. It was a slow, inexorable process, not like my body had to get rid of something bad that I ate. Had also not been sick enough to vomit in years, then it happened three out of four weeks in a row. Switched back to Victoza, no more headache and vomiting. Ozempic was more convenient as it is a weekly shot, but I'd rather not be sick one day a week. The vomiting was awful."

3 / 10
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31 Report
  • Seh...
  • November 6, 2019

Semaglutide for Type 2 Diabetes "Horrible diarrhea after just the first use. Headache. A LOT of lightheadedness. Not pleasant, but I can live with it. I received a sample from my doctor with 6 doses. When I went to have it refilled, there were issues with my insurance (BCBS). The medication is listed as $12,051.19 before insurance! I returned to the pharmacy today. With insurance, 'only' $1,897.99. I will not be getting this medication refilled given the horrid side effects and the IMMORAL pricing. C'mon people, this medication does not cost that much to manufacture."

3 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.