Semaglutide and Headaches: What Users Say (Page 5)

• Anonymous
• Taken for less than 1 month
• June 14, 2023

For Weight Loss (Obesity/Overweight) "Took one injection of 0.25 mg so far, and 5 days later I’m still extremely nauseous, have thrown up 4 times, and have a really bad headache. I can definitely say I’m eating very little, so I’ve certainly lost weight!"

• Bra...
• March 15, 2021

Semaglutide for Type 2 Diabetes "Ozempic lowers my blood sugar. I have found in the 4 weeks I have been taking it, I have lost weight (not sure how much, but it's noticeable for the first time since I was diagnosed with type 2 diabetes 6 months ago). I am struggling to decide if it's worth being sick 2 days a week. I have extreme nausea (like I have mild food poisoning), a terrible headache, and I'm exhausted. The rest of the week, I feel fine. It is the two days following the injection that I have these awful symptoms. The first three weeks I was at 0.25, I found by week 3 they were milder symptoms, but this week I have increased to 0.50, and I am extremely sick with nausea and headache. I've found the GI issues mild, but I am on other medication that constipates me. I feel this may have been worse otherwise. I am going to tough it out for the next few weeks until I get to 1, as I found a decrease in the nausea over the first three weeks until I increased the dosage. However, if this is a constant side effect, I will 100% be discontinuing this medication."

• And...
• Taken for less than 1 month
• October 18, 2019

Semaglutide for Type 2 Diabetes "I started Ozempic injections 3 weeks ago (by the way, I live in the UK). I also take Metformin and Foxigra. I had a slight headache and nausea, which I seem to get a few days after the injection. I don't find I get any appetite decrease that much, and I've put on weight this week. But sticking with it, so we shall see."

• edw...
• Taken for 1 to 6 months
• January 28, 2025

Semaglutide for Type 2 Diabetes "Insurance is Medicare Advantage AARP United Health. The 1st 3-month supply was $130. The 2nd 3-month supply was $450. I expect the medication will not be affordable for the future. There was no advantage in the first 3 months taking the 3 mg dosage. A1C is 7.4% from 7.6%. Now taking the 7 mg dosage; waiting for my next doctor evaluation on Feb. 26, 2025. I get frequent headaches, dizziness, upset stomach, bloated feeling, and sleepy/low energy levels. No weight loss."

• 2nd...
• Taken for 1 to 6 months
• October 21, 2024

Semaglutide "I lost 20# in 5 months over a year ago and gained it all back in 6 mos. The top side effects then were nausea, constipation, bloating, and big hair loss, strangely starting a month after discontinuation and lasting 5 mos. Much hair grew back. I started up again a week ago and more, this time unbearable side effects. Horrible headaches at the base of my skull, acid reflux that chokes me and burns my throat at night, flashes of light and wisps of wind in my face at night, nightmares, hair coming out in swaths, erratic high BP (I have high BP, but it was under control before O.), bad joint pain (hips especially), extreme urinary incontinence (swelling down there with pee dribbling), and extremely emotional (incessant crying) just 5 minutes after injection. Five minutes after the second shot (second week), all the above that had “slightly” eased up came back full force! Husband again losing weight with doable nausea and blah feeling. *I have a lot of side effects to most meds."

• ker...
• Taken for 1 to 6 months
• June 26, 2023

Semaglutide for Type 2 Diabetes "It kept my weight and my blood glucose levels down, but I experienced dreadful night sweats, lethargy, disorientation, and headaches."

• Ley...
• Taken for 1 to 6 months
• June 3, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "From the initial starting dose until I went up to 1 mg, the whole 6 months was a roller coaster of nausea, headaches, and uncontrollable vomiting. The nausea was always followed by throwing up 5-7 times per day. If I ate or drank anything with too much sugar (including fresh orange juice), then I would throw it up within 30 mins. The sulfate mouth smell, along with the vomiting, was difficult and embarrassing. Exhausted and tired feeling, along with feeling depressed and hating/disgusted by food, is how I felt. I did lose about 8 kgs before moving on to Saxenda. Get ready for Ozempic to destroy your life for a few months if you want to lose weight with it."

• Cal...
• Taken for less than 1 month
• May 12, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "My experience with Wegovy has been a rollercoaster. In the first week, the 0.25 mg dose was great. In the second week, I started feeling the side effects of nausea, burping, gas, diarrhea, and bloating. I noticed that I did eat more. Make sure your portions are small and stick to fruit and vegetables. Soups and not greasy processed foods. You may feel sick and will take longer to digest. I am currently reconsidering if I should continue. I am not sure if I want to experience the side effects at a higher dose. I feel terrible all the time and have a headache. I feel exhausted all the time."

• Haw...
• Taken for less than 1 month
• May 11, 2023

For Weight Loss (Obesity/Overweight) "Three days ago, I took my third injection of 0.25 mg. I am so, so sick. I have been sick with nausea and burping since I took the first injection, but this week is the worst. Nausea, vomiting, dizziness, headaches. Today was so intensely bad I almost went to the ER. I’m trying to keep going as I desperately want to lose weight. I’m down 10 lbs in 17 days, but I’m so sick I can’t even eat healthy foods. I don’t know if I’ll be able to do the next injection, this has been so horrible. My doctor also prescribed Zofran for the nausea, but it’s not helping. Will the side effects ever stop, or should I just give up?"

• San...
• Taken for 6 months to 1 year
• July 10, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "I am about 6 months in, and at 2.4 per week, I have lost 17 lbs. It does work to curb your appetite, but I always feel sick. I have noticed I have developed severe migraines after week two, but kept going. I am currently on migraine medication, Ajovy, and it is not helping. Sometimes, it comes with blurred vision, which gets a bit better once it gets closer to taking it again. I have gone to the ER three times over 6 months with severe headaches, but nothing helps. It has really impacted my way of life, and I do feel like a worse wife and mother because I am always sick and have a constant headache that never, ever goes away. I gave it a go, but at this point, the cons outweigh the pros for me. I did stop Wegovy two weeks ago and noticed an improvement in my headaches and my menstrual cycle. Headaches basically gone, why didn't I stop sooner?"

• Wen...
• Taken for 1 to 6 months
• March 8, 2022

Semaglutide for Type 2 Diabetes "I have been on Ozempic at the lowest dose for 4 weeks. The first week was brutal, with stomach pain, nausea, vomiting, and headache, however, I injected the second week in my thigh and the side effects waned. It appears to be lowering and leveling my A1C. I'm nervous about increasing my dose next week. I can manage a week of discomfort as long as it is short-term. My body does seem to be getting used to it. I'm willing to work with it as long-term benefits for me outweigh the short-term discomfort. I may change my mind as time goes on, as these horror stories have me concerned. So strange that there is such a wide range of patient experiences...both good and bad."

• Lin...
• Taken for 1 to 6 months
• October 12, 2021

Semaglutide for Type 2 Diabetes "I have been sick ever since I started taking Ozempic: diarrhea, headaches, weight loss, nausea, throwing up. It's a bad medication."

• Meg...
• Taken for less than 1 month
• March 16, 2021

Semaglutide for Cardiovascular Risk Reduction "I started this medication last week on Tuesday. The first two days, I had a headache and a flu-like feeling. Throughout the week, I felt nausea almost daily, bouts of diarrhea, and bloated. Today is my second dose of 0.25, and I lost 4 pounds in 7 days (probably the fact that anytime I eat, my next bowel movement is diarrhea). I have felt a general unwellness for the last 7 days and am anxious about how this week will go, as I haven't been able to accomplish what I normally am able to. If this week gets worse and I start vomiting and being really unwell, then I will stop taking this medication. I definitely don't have the same appetite I did before, and my junk food craving has basically been vanquished, however. If the symptoms don't peter out or they get worse, I don't see the point, as it affects my son's life as well when I can't be the best mom I can be."

• Jun...
• Taken for less than 1 month
• March 13, 2021

Semaglutide for Type 2 Diabetes "I took Ozempic for the first time today around noon. I had a headache about 19 minutes after taking 0.25 mg. About an hour later, I developed red welts and a red, itchy, burning rash down the inside of my right thigh! I thought it would go away eventually, it’s been 9 hours, still there. The headache is gone, no stomach problems. However, my numbers have been around the low 109's to the low 200's after a meal. After eating soup for lunch, my glucose level shot up to 378! Has anyone else experienced this? I hope I’m able to tolerate this drug."

• Dim...
• April 7, 2020

Semaglutide for Type 2 Diabetes "Been using Ozempic for 7 weeks, lost 12 pounds. I also take Xigduo and Lantus at night. Gas, nausea, headache, and a few low A1c. But my number is down from 8.1 to 5.4. For the gas, I find that Gas-X helps. And for the nausea, I sip on cold water and keep my meals small. I haven't thrown up yet and no constipation or diarrhea."

• Val...
• Taken for less than 1 month
• February 14, 2020

Semaglutide for Type 2 Diabetes "I’m a nurse. I started this med and unfortunately the nausea, gastritis, dizziness, and headache continuing into week 4 is simply not worth it. I can’t lay in bed and be miserable, which is what this does to me. At first, I actually thought I had a GI Bug. If there is any other choice, do not put yourself through this."

• Ice...
• Taken for less than 1 month
• November 4, 2019

Semaglutide for Type 2 Diabetes "OMG ... it’s not me. Dr. started me at .5 of Ozempic, first day after injection pretty much okay, then came nausea, stomach ache, headaches, then just dulled, gassy (didn’t know the burps were part of it but that increased), diarrhea, feeling beyond blah. I went to work and struggled through the day for 4 days like this. The first week wasn’t sure if it was the shot or some food, so I tried the Ozempic again. The second week was a little better, so I decided I’ll try the smaller dose. Today is day 2, but this morn, there’s the nausea, stomach ache, a little bit of headache, but lesser amounts. Despite the thought of weight loss, might be heading back to Januvia (Farxiga got the yeast infection, but it was cheap, $15 for 90 with insurance)."

• JLa...
• Taken for 1 to 6 months
• May 3, 2019

Semaglutide for Type 2 Diabetes "I've been on Ozempic 0.25 for five weeks, it's great for losing weight, but the side effects are not worth it. Let me review what Ozempic has been like. The first three weeks were okay, and then I started noticing nausea, stomach burning, headache, dizziness, upper back pain, severe constipation, and feeling very tired and depressed. I ended up in the ER with a mild pancreatic attack and high lipase levels. I've had no desire to eat or even drink water. It makes me gag, and I used to drink a lot of water. I'm done with these injections. I will stay on my metformin, but I can do better on a healthy eating lifestyle than on Ozempic and all the negative side effects. Quality of life has gone from a 10 to a 1, and that is not me. I'm taking my life back. It's really just healthy eating, and we can all do that with willpower. Good luck to everyone else."

• Hoo...
• May 17, 2018

Semaglutide for Type 2 Diabetes "Initially began Ozempic 0.25mg for 4 weeks. Side effects were tiredness, constipation. My fasting blood sugar numbers were lower in the morning. When I began the 0.50mg dose at 5 weeks, I had nausea, dizziness, and lethargy the day following the first dose. The second day following that dose, I felt about 70% better. With the second dose of 0.50mg, side effects were less severe, some minor nausea, headaches, and the tiredness continued. I hope that these side effects disappear. I plan to take this medication until I get my 3-month labs, and I expect that my A1c will be down significantly. It was at 5.9 in July of 2017. Due to the stress of caring for a dying relative from September through December, it jumped to 9.3. At my next appointment, my doctor suggested I try Ozempic in combination with Metformin 500mg twice a day. I received a 3-month discount card and have not yet checked with my health insurance provider to see if it will be covered. I am an active 61-year-old female, but type 2 diabetes does run in my mother’s family."

• Ano...
• Taken for less than 1 month
• June 18, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "Lost 10 lbs in 3.5 weeks, but the side effects mean I will be stopping. Diarrhea, vomiting, stomach cramps, headaches, bloating. Felt ill most of the time. Working and traveling problematic due to having to be close to a toilet!"

• Vic...
• Taken for less than 1 month
• December 9, 2024

Semaglutide for Type 2 Diabetes "I have been taking .25, and I am suffering nausea, headache, and bloating. I thought it would be better after the first 2 weeks, but it's worse. I think I will have to stop taking it. I have not seen any benefits."

• lee...
• Taken for less than 1 month
• May 4, 2023

For Type 2 Diabetes "On my second week of semaglutide for my diabetes and have had severe abdominal and back pain, waves of nausea, headaches, bloating, and heartburn, not really sure it's worth taking it, especially when I don't really understand why it's been released to the public due to the risk of cancers like pancreatic cancer, especially as I'm a diabetic and already at risk of it. But I am going to a diabetic educator and will be getting the latest and safest medicines and advice, so if I'm told to stop it, I will... but I am persevering with it at the moment. It's a pity though, as I have heard it does work to control diabetes, and as I'm older now and in need of ridding myself before it's too late. I feel I must, but it has been dreadful so far with these side effects and especially at work. Hopefully it all works out or I will have to stop taking it... it's also hard when I'm supposed to stay on it, but it's in limited supply."

• Mar...
• Taken for less than 1 month
• March 26, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "Just started 2 days ago and am afraid to continue. Flu-like, headache, depression, and anxiety ramped up. Feel foggy and not wanting to get out of bed."

• Pri...
• Taken for less than 1 month
• May 20, 2022

Semaglutide for Type 2 Diabetes "My doctor put me on this because I was pre-diabetic, and he said I was insulin resistant. Since I’ve been taking it, I’m not as hungry, but my head hurts, and I always feel dehydrated, and so I’m peeing all day. I feel short of breath, and my chest has been feeling pains. I’m also experiencing constipation and constant light-headedness, and I’ve only been on it for 2 weeks. I may give it another 2 weeks, but not sure if the side effects are worth all this. I feel no energy, and my legs are always sore, and I’m so tired all the time. My way of living has suffered because I’m too tired to do anything and feel yuck all the time. Trying not to be frustrated because if this doesn’t help me, he wants to put me on Jardiance, but I hear so many horror stories about that one. This one isn’t as great as everyone said it would be, so who knows, maybe Jardiance will be better for me."

• Jam...
• Taken for 1 to 6 months
• February 2, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "I’ve been on Wegovy (Ozempic) for 10 weeks, first at 0.25 mg and now on 0.5 mg. I have not lost any weight (but not gained any). It has not curbed my appetite, and I still crave sweet stuff. I have had a few side effects, but the worst is constipation, and I have not had a normal poo since I started. I also have a headache, get dizzy if I stand up quickly, and my hair is falling out somewhat. I eat high fiber and take psyllium husk, and still no poo in a week sometimes. I would stay on it at higher doses, but the cost of £155 per month is not worth it if no effect so far. Disappointed because so many have a good result with this medication."