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Semaglutide and Headaches: What Users Say (Page 3)

Brand names: Ozempic, Rybelsus, Wegovy

Reviews for Semaglutide

Commonly mentioned side effects
  • Chr...
  • Taken for 1 to 6 months
  • March 28, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "I started on Wegovy in December 2021. In the beginning, it made me sick to my stomach. I had the belching and very little appetite. When I got to 0.50 mg, oh my God! I could hardly eat anything for a couple of days. I was scared to go to the next level, but I did. When I was on the 1 mg dose, I didn't have any issues. Once I got to 1.7 mg, it wasn't bad either- a little belching, headaches for a couple of days, upset stomach, and constipation kicked in. Getting ready to start the maintenance level of 2.4 mg, and let's pray I tolerate it well. So far, I have only lost about 27 lbs, trying to lose about 17 more to get to my ideal weight. This is the best medicine that has helped me lose and, prayerfully, keep it off. I have learned how to eat small meals and make better choices in foods."

9 / 10
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  • mas...
  • Taken for 6 months to 1 year
  • June 3, 2021

Semaglutide for Type 2 Diabetes "So far I love the results. My A1C was 9.8 and now it is 5.6. From August 2020 to now, I lost 67 lbs with diet and working out from the first week. I had a headache, but after, nothing but positive results from low blood sugars ranging from 80 to 110. I kept checking, I thought it was wrong, lol, but overall I tell everyone that is type 2 to speak to their doctor and see if it works for them."

9 / 10
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  • Uni...
  • May 27, 2021

Semaglutide for Type 2 Diabetes "I'm on my second week. I've lost 2-3 lb. I feel less hungry and don't lose control after I eat. I don't constantly think about food. If I overeat, I feel sick after. I still want sweets, but I can eat very little and feel content, almost put off by it. I feel the most side effect symptoms right after the injections. The side effects have been mild, probably because I put the injection into my thigh instead of my stomach. They include: bowel movements, weird taste in mouth, headaches, tiredness, tummy ache, and earache. But very mild. I'm excited to move up to a full dose."

9 / 10
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28 Report

Frequently asked questions

  • Lin...
  • Taken for less than 1 month
  • May 2, 2021

Semaglutide for Cardiovascular Risk Reduction "I have been taking this medication now for 2 weeks and 1/2 for weight loss purposes, and I started with 1 mg recommended by my friend that lost 15 pounds with it in 2 months. Well, I got very nauseous, dizzy, and headaches, which got better in the 2nd week, but I feel very tired all the time, very low energy, and started having shortness of breath. I lost 5 pounds so far, and I'm still not feeling well. I do get full faster when I eat, but it has been very hard dealing with the side effects. At this moment, I'm not sure if I will go on with it or not. My inspiration is my son, who was 242 pounds and now is 205 after 1 month and 3 weeks of being on Ozempic. It has truly changed his life, and he is super happy, he calls it the miracle drug. I will keep you guys posted on my journey."

9 / 10
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  • Joa...
  • Taken for 6 months to 1 year
  • March 16, 2021

Semaglutide for Type 2 Diabetes "I have been on this medication for 10 months. I started with .25 for 4 weeks, then increased to my prescribed dose of .5. My doctor and pharmacist correctly recommended this gradual increase. However, after beginning the .5, I became very nauseous, had diarrhea and/or constipation, terrible headaches, and all-around lethargy. It was awful. I toughed it out for 2 weeks, but that was it. At the advice of my pharmacist, who happens to be a diabetic counselor, I went back down to .25 for a couple of weeks, then very gradually increased my dose. A few extra clicks of the pen each week until I reached .5. Success!! Now I have no side effects and have lost 25 lbs, which is a significant amount for me. My appetite is very low, and I just don't experience any cravings that I used to. My guess is this very slow, gradual, almost click-by-click increase may be effective for a lot of people. I have read through many of these reviews and cannot imagine jumping right in with a .5, however, I am not a doctor, so..."

9 / 10
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  • Dck...
  • January 13, 2021

Semaglutide for Type 2 Diabetes "I’ve been on Ozempic for 8 weeks, .25 starter dose for the first 4 weeks; it suppressed my appetite, a couple of mild headaches, and intermittent nausea. Moved to .5 at week 5 and have no desire to eat at all. It’s almost a problem as I feel so weak and have all-day nausea. Hard to tell if the nausea is from not eating, Ozempic, or both. At week 6, I also started taking Humira for spondyloarthritis; the combined side effects are brutal. Sick nearly 24 hours a day, constant nausea, vomiting with any exertion. Backed off the Ozempic to .25; the side effects are better, but still troubling. As a positive, I’ve lost 30 lbs in 8 weeks, all from not eating as I feel too sick and weak to walk or work out. The docs prescribed Zofran 8 mg po every 8 hours as needed. It helps, and I do manage to eat a couple of small meals. Weigh the benefits and downsides, but it does work. A1C dropped from 8.7 to 7.4 in the first 8 weeks and should continue downward with prolonged use and accompanied weight loss."

9 / 10
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21 Report
  • oze...
  • Taken for 1 to 6 months
  • January 29, 2020

Semaglutide "I have been on Ozempic for 5 full months to help me lose weight. In that time, I have lost exactly 60 pounds (I had about 100 to lose). I was on 0.25 mg for 6 weeks, moved up to 0.5 mg thereafter, and have been on 1 mg for the past 4 weeks. I certainly experience stomach pains, headaches, absolutely no appetite, severe constipation, feel full almost immediately after eating more than 3-4 bites, and I am not sleeping as well. As of right now, the benefits are outweighing the negatives. I do not plan to stay on Ozempic long term because the possible thyroid cancer/tumors scare me. I am nervous upon stopping Ozempic that the weight gain will come right back."

9 / 10
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More FAQ

  • Liz...
  • Taken for less than 1 month
  • December 16, 2019

Semaglutide for Type 2 Diabetes "On the fence. Took my first shot of Ozempic .25 last Wed at the doc's office. I was nervous as I couldn't tolerate Metformin's side effects. But she reassured me this was gonna be the answer to my prayers, so I agreed to try it. First day I was fine, then they hit. Woke up feeling dizzy, nauseous, and shaky. My fasting blood sugar was 157. Lower than it's been in quite some time. Ozempic does its job. My BS has been managed quite well. I definitely don't have an appetite. Have to make myself eat and drink. Have very low energy. Tired all the time. Aside from that, it's the other side effects I'm having trouble living with. Waking up in the wee hours of the morning clammy with severe nausea, mild headache, and dizzy. But it's only been 6 days. The constant nausea, dizziness, and headaches are almost unbearable. Not sure if I'm gonna continue. If the effects are like this now, what are they gonna be with the increased dose? There's gotta be a better way!"

9 / 10
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  • Hoo...
  • Taken for 1 to 6 months
  • July 30, 2019

Semaglutide for Type 2 Diabetes "Have been on this med for about 6 weeks. Started at 0.25, now at 1 mg. I have to say I am loving my numbers now. Have lost 12 lbs, and the only side effect is mild stomach cramps occasionally and a slight headache. I only hope the trend continues, since some posts have me concerned."

9 / 10
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  • Jpa...
  • Taken for 1 to 6 months
  • July 15, 2019

Semaglutide for Type 2 Diabetes "I’m into my 5th week and have increased to .5. In addition to diabetes type 2, I have PCOS and IBS. I’ve been doing well so far, other than a mild headache and stomach upset. My appetite is obliterated, and I have to make sure I’m eating regularly. Otherwise, nausea and lightheadedness end up being my trigger to eat because I’ve gone too long in between meals. It’s been confusing for me, as overeating has always been an issue. Now I have no desire to eat and am working at adjusting by eating small portions throughout the day. I’m definitely losing weight, which is much needed. In addition to Ozempic, I take Metformin and Tradjenta, which I’ve been on for a very long time. This week, my fasting blood sugar decreased from 155 to 135. That makes me happy."

9 / 10
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  • Bet...
  • Taken for less than 1 month
  • July 5, 2019

Semaglutide for Type 2 Diabetes "Only second week in on the lowest dose. Feel lighter, no hunger at all. Suffering from nausea, wind, and headaches. I would really like to go the distance with this medication. I have overeaten for years and am wanting this to work. Not thinking of eating is quite liberating."

9 / 10
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  • Dan...
  • Taken for 1 to 6 months
  • March 24, 2019

Semaglutide for Type 2 Diabetes "I’ve been on this med for 7 weeks. I’ve lost 25 lbs and my daily blood sugars range from 60 - 90. I use it along with 500 mg Metformin. The first couple of weeks were hard with nausea and stomach cramps. I also had the headaches that others have mentioned in the first couple of days. In week 3, I increased from 0.25 to 0.50. Then came the diarrhea. It wasn't too bad, I was just happy that I could go. I’m now taking 1.0 and experiencing sulfuric burping. Ugh! After doing some research on home remedies to help with the burping, I’m trying a spoon of apple cider vinegar. If you can make it through the first few weeks and you can be somewhat disciplined, you will notice a huge difference in how you feel. In my opinion, the side effects are manageable when I compare the weight gain while taking Insulin. BTW - I’m not severely obese. Prior to being on this drug, my weight was 205, and I’m 5’9 and 47 years old. I hope this is helpful to someone."

9 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • July 13, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "Have been using Wegovy about 6 months now, down 39 pounds. Some side effects like heartburn, rotten egg burps, and headaches at times are pretty bad. I’ve also noticed my taste buds have changed a lot! Either the food tastes different or it makes me gag within a few bites."

8 / 10
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  • Mar...
  • Taken for 1 to 6 months
  • May 24, 2025

For Weight Loss (Obesity/Overweight) "I have had all of the less common side effects, primarily belching, excess gas, swollen stomach, headache, and nausea. I’m not sure yet if eating certain foods causes it. I ate Indian food, and it was awful for two days. But I feel okay generally, and it seems to be working, so I’m happy about that."

8 / 10
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  • Ano...
  • Taken for 2 to 5 years
  • May 20, 2025

Semaglutide for Type 2 Diabetes "Nausea on a regular basis over two years of having it. Severe weight loss, even when not needed, as unable to face food. Blurred vision and pain in the eye. I don’t recommend it just for weight loss. I started on 0.25, going up to 0.5. Constant headache because of eye pain. I came off insulin, but am now stopping Ozempic, can’t put up with eye and headache. I would rather have insulin four times a day."

8 / 10
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  • Jul...
  • Taken for 1 to 6 months
  • May 11, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "Good with some mild nausea and headache hours after injecting. Lost 7 lb in first month. I do not have cravings and I am satisfied with small meals."

8 / 10
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  • Rif...
  • Taken for less than 1 month
  • February 11, 2025

Semaglutide for Type 2 Diabetes "When I heard about Ozempic, the insulin is being used as weight loss, then I thought it wouldn't work for me as a type 2 patient. With another insulin, I was tired and frustrated. So I asked the specialist to try Ozempic. She agreed. I have just started this 5 days ago, so far, I have had headache, vomiting, but no stomach upset. With 2.5 mil dosage and regular medication, it's working. Hopefully, it will help me in the long run. Thank you."

8 / 10
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  • Pam...
  • Taken for less than 1 month
  • December 19, 2024

Semaglutide for Type 2 Diabetes "So this week I started on .25 on my Ozempic. I'm pretty excited to see how I do. The second day I was really nauseated and had a headache, but now I feel better. But let's see with the next shot."

8 / 10
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  • Rih...
  • Taken for 1 to 6 months
  • May 20, 2024

Semaglutide for Type 2 Diabetes "I have type 2 diabetes and I am obese. I started this medication in November 2023. I stopped using it for three months due to a shortage in the market in my country. I used 0.25mg for the first month, 0.5mg for the next three months, and 1mg for two months. The last dose of 1mg was taken on May 17, 2024. In November, I weighed 91kg, and I have reached 75kg or perhaps even less now. For my health, I feel significantly better while working or going upstairs. Regarding side effects, I experienced tiredness, vomiting, headaches, nausea, constipation, and stomach pain."

8 / 10
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  • Jan...
  • Taken for less than 1 month
  • June 2, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "Started this past Tuesday, and all is going well. A headache in the morning, but each day I have lost one pound. Very excited about trying to lose this weight."

8 / 10
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  • dee...
  • Taken for less than 1 month
  • April 7, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "Just completing week one at the low dose. I did the research after being given the prescription and expected there would be side effects, so planned for it. I bought antacids and Gravol and waited. The injection site is the thigh, and I got a small bruise. I did not feel the injection at all. I had minor side effects on day one, of a headache and feeling queasy. Since then, only some belching if I overeat. It is like my brain suddenly recognizes I have eaten."

8 / 10
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  • Huc...
  • Taken for 1 to 6 months
  • March 13, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "OK, I gained over 40 pounds due to injuries, then COVID. I started at 257 lbs, today I'm at 237, and I'm on the second month of 0.5 ml injection. The side effects are a pure nightmare! But as I got to 0.5 ml, they taper off. I carry Tylenol for the headaches, and my gastroenterologist prescribed Carafate for indigestion, Pepto-Bismol works too. If you can hang in there for the first 2 months, you'll be good."

8 / 10
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  • C01...
  • Taken for 1 to 6 months
  • July 6, 2021

Semaglutide for Cardiovascular Risk Reduction "3 weeks in... Initially prescribed for weight management. While my appetite's drastically reduced, I've experienced headaches, some brain fog, and felt a little under the weather. Nausea slightly though it reduced day by day. Fatigue's unbearable. I typically have an upbeat, positive attitude and noticed a not-so-good version of myself just recently. Contemplating discontinuing treatment as excited as I am for the weight loss aspect of it :("

8 / 10
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  • TN ...
  • Taken for 1 to 6 months
  • October 5, 2020

Semaglutide for Type 2 Diabetes "I've been taking Rybelsus, along with metformin and Farxiga, for over 3 months. I had some minor diarrhea/constipation with the 3 mg that worked itself out quickly, but I lost over 5 lbs and A1C went down over 1 pt (8.3 to 7.2). Just started the 7 mg dose 5 days ago. So far, the diarrhea is a lot worse, and I'm having a lot of dizziness/nausea/fatigue/headaches, but I'm hoping it'll stop soon. I seem to start feeling worse about 5-6 hrs after taking the pill, so I'm sick in bed for hours in the afternoon and evening lately. Not good, as I'm a disabled housewife with two special needs adult children who depend on me. Not sure how someone who works a 9 to 5 job would be able to handle this transition period. If it doesn't sort itself out within a couple of weeks, I'll call my doctor. One tip: keep some saltine crackers and eat a few every hour or so. I know, against diabetic diet, but that and plenty of water help the nausea."

8 / 10
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  • lil...
  • Taken for 1 to 6 months
  • January 9, 2020

Semaglutide for Type 2 Diabetes "Thank you all for your comments. I didn't realize the headaches were from the Ozempic. I have not suffered from the runs, but did get the reflux. I have had it before and already take meds for it. It is a relief to see my symptoms are, while not great, fairly normal. I am on week 4 at .25 and will go up to .5 in two more weeks."

8 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.