Lupron Depot User Reviews & Ratings (Page 2)

• LJo...
• December 15, 2014

For Endometriosis "I was diagnosed with Stage 4 endometriosis and was prescribed Lupron. After reading all of the horrible reviews and side effects, I was terrified to try this. After chatting with my doctor, we both agreed that this would be the most aggressive treatment as my husband and I would like to get pregnant one day. I am on month 3 of the shot, and I have to say that I am pleased. The worst thing are the hot flashes. For me, they are at least 10 times a day! But I will take that over the excessive cramping and pain any day. I feel minor cramps occasionally during the time I would normally have my period. I have experienced no depression, weight gain, weight loss, bleeding, joint pain, etc. I am hoping after the treatments I will be able to conceive."

• Ann...
• Taken for 6 months to 1 year
• May 31, 2015

For Uterine Fibroids "I had extremely painful periods and constant bleeding. My doctor started me on the shot in Jan. and had the second one in March. Best thing I ever did. No bleeding after the 1st month and no pain after the 2nd month. Side effects were, in my opinion, mild. Worst were the hot flashes, but in my opinion, worth it. Doctor only wanted me to have 2 shots, so after June, going to see what happens. I don't want to get on any birth control, so will see what happens. I'm really hoping this makes it all better."

• nel...
• June 19, 2017

For Uterine Fibroids "I had my heavy period and strong and constant pain, which stops me from doing my normal life for more than 5 years. Since I have started to inject this Lupron, it has changed my life. After all those painful years, now I have had 4 injections already and go for the fifth one. The only side effect I had is hot flashes, especially during nights, and some bone pain, which are nothing to compare with the pain I had for more than 5 years. It is really worth trying if you are experiencing heavy bleeding and pain."

• Anonymous
• Taken for 1 to 6 months
• July 15, 2012

For Uterine Fibroids "I had to get the 3-month Lupron Depot shot to help shrink my uterine fibroid and to help minimize the bleeding before surgery. After reading all the reviews on the shot, I was very scared to get it, but I am now going into my third month on the shot with minimal side effects. My doctor did recommend that I continue my birth control pills while on the shot to help add a little estrogen back into my system. I'm not sure if that's what helped me with the side effects. All in all, everyone's body reacts differently."

• cda...
• November 13, 2015

For Endometriosis "I really feel it is important to share my experience with this drug. I did extensive research before making my decision to start the Lupron Depot pack. I was scared, and I prayed to have a good experience since most reviews for this drug are awful. I am grateful to be able to give this drug TWO THUMBS UP! I am taking one-month shots combined with the add-back pills. The first month, I experienced NO increase in symptoms. I bled for the first month and a half, now my constant bleeding is gone! For the first month, I experienced very mild hot flashes, now none at all. My quality of life is 110% better, and I am pain-free. I am so grateful I took a chance on this medication. I finally got a break from the constant pain and exhaustion from endo."

• K S...
• Taken for 1 to 6 months
• September 27, 2019

For Prostate Cancer "I was given this poison for the first time, May 2nd, 2019. The doctors/nurses would NOT tell me the name of it. Only referred to it as: hormone therapy. 60 seconds AFTER the nurse shoved a 22.5 mg 3-month dose of it into my butt. The doctor's assistant walked up to me, handed me a booklet: 'Understanding Lupron Therapy', said: You better TAKE THIS HOME AND READ IT, she laughed, turned around and said: 'see ya'. When I got home, I turned to the 1st page. It said: 'side effects': 'heart attacks, strokes, bone damage, diabetes, AND, 'sudden death......' I was so angry. She injected me with a POISON. For 10 weeks, I was so angry, mad it was indescribably bad. The worst 3 months of my life!"

• sev...
• February 8, 2019

For Prostate Cancer "My father has prostate cancer, and he was given the Lupron shot. Everything was going fine for my dad until 2 weeks after the shot. He started having side effects from the shot. Now, before I go any further, let me just say, if anyone has PTSD, do not take this drug. My father started seeing things that were not there, hearing things that no else could hear, and smelling things that no one else could smell. Now, not everyone will have the same side effects, but if you have PTSD, it will kick it into gear. This might be the right treatment for you, it is not for my dad. Again, if you struggle with PTSD, this may not be the treatment for you. I hope this was helpful in some way."

• Lex...
• October 5, 2015

For Endometriosis "Don't do it! I got the 3-month shot 1 month ago and have had these symptoms so far: constant and severe pelvic pain, sharp lower back pain, pain when the bladder is full and when emptying, lots of migraines and headaches, nausea, vomiting, high anxiety, extreme fatigue, very low mood swings, loss of appetite, and insomnia. The worst symptom of all is the severe depression, I have had several thoughts of suicide. I would rather deal with just the pain than all of these together. I was told by my doctor the only symptom I would get is hot flashes, and she had only heard of success stories with this drug, that was a total lie. If you react badly with other birth controls, do not do Lupron, it's a living nightmare!"

• End...
• Taken for 1 to 6 months
• September 24, 2014

For Endometriosis "Stage 4 endometriosis. I've been on Lupron for 3 months and will get another injection next week. I've had a few hot flashes, about 1x/day occasionally, but not every day. I have stayed below my original weight by about 5 lb. Some moodiness/occasional depression. But overall, I haven't had any major problems! I was very worried about side effects before starting Lupron, but am glad I did it. I want to be healthy! I'm getting married next weekend also, so have been planning a wedding at the same time. We're hoping to get pregnant next year!"

• Anonymous
• Taken for 1 to 6 months
• September 29, 2012

For Uterine Fibroids "I had my first Lupron shot on August 10, 2012. I started bleeding on August 21, and it is now September 29, and I have been bleeding ever since. I've had a problem with anemia due to two fibroids. I had my second Lupron shot on September 10. I'm not sure I should continue this because I'm scared I won't be able to have surgery on November 2 due to anemia caused by blood loss. Overall, Lupron is not working for me."

• 1Sw...
• Taken for less than 1 month
• January 29, 2014

For Endometriosis "I was on Lupron for 6 months back in 09. The side effects weren't bad for me at first, but I have to say the night sweats were the worst! I just hated waking up in the middle of the night, needing to shower because I was so sweaty. However, I was pain-free! I had an AWESOME summer and went camping, mountain biking, traveling. My pain has slowly come back over the years, and my (new) doctor just gave me my first shot of Lupron yesterday. I am hoping it works just as well as it did the first time. I want to be me again."

• blu...
• January 10, 2020

For Prostate Cancer "69 years old. Had seed implants 16 years ago. PSA slowly creeped up, and due to an incompetent doctor, it spread to my spine before getting any treatment. Thankfully, I made a visit to another MD and got first-class care. I just had my 2nd Lupron injection (3-month interval). No side effects other than mild hot flashes. I keep a strenuous exercise program in place, and I think that helps a great deal. On Zuniga also. PSA down to 0.50 from high of 17."

• And...
• November 22, 2017

For Uterine Fibroids "I was diagnosed with a 13 cm fibroid. The doctor wanted to shrink it to be able to perform a laparoscopic hysterectomy. I was having constant heavy bleeding for months on end, even the tranexamic acid wasn't slowing it down. The first drug we tried was Fibristal. It was supposed to slow the bleeding and shrink the fibroid. I took this for 6 months, and it did absolutely nothing. The doctor then suggested Lupron Depot. The first week on Lupron was hard. Bleeding was much heavier than before (which was already horrible). But by week 2, the bleeding completely stopped. By 5 months on Lupron, my fibroid had shrunk to 11 cm. A bit of hot flashes, some fogginess/irritability, but that's normal for me...lol."

• MoM...
• Taken for 1 to 6 months
• May 6, 2020

For Endometriosis "I was put on Lupron Depot for three months for endometriosis. I received an injection every month. My treatment started in January and ended the first Saturday in March 2020. The side effects weren't all that bad. I got my period on my dose, but it eventually went after that. I had, however, severe headaches that made me dizzy, experienced some mood changes (mostly anger), painless sex, hot flashes (manageable), and joint pains at the end of my last shot. The joint pains are mostly in my knees and fingers, but I only experience those after waking from a nap. Once I get up and start moving about, they disappear. I now await my cycle to return. It has been eight weeks since my last injection, and signs of my period returning are back. I'm spotting and experiencing mild cramps. All in all, my experience wasn't bad. Hope this helped someone. Oxoxox"

• Woo...
• Taken for 6 months to 1 year
• April 9, 2020

For Prostate Cancer "I’m a 66-year-old male who was diagnosed with moderately aggressive prostate cancer with a Gleason score of 8 and PSA of 7.2. I’ve had 2 Lupron injections, which have caused the following side effects: a chemical smell, muscle weakness, hot flashes, fatigue, PSA - <.01, insomnia, anemia, decreased leukocytes, decreased size of penis and testicles, and bone pain in the back and sacrum. I have one more shot in July. I was taking Zytiga for a while."

• Not...
• Taken for 1 to 6 months
• January 22, 2015

For Endometriosis "I am 37, and for the most part, have been very healthy... never pregnant and married for three years. I have had an ovarian cyst, but have been controllable. On Nov. 9, 2014, I went to the ER, and the next day I was having a mass and 6' of my colon removed due to endometriosis. I had stage 4. My OBGYN suggested this shot. I read all the reviews and was VERY leery of starting it, but I just took my second shot. It has not been so bad. I have experienced hot flashes and weight gain. I have about 4-6 hot flashes a night, but no sweats yet. I am hungry ALL the time, and it seems the more I eat, the more I want. I can't seem to get full. I have gained 10 pounds in about 6 weeks. My mood has been good, though. I have had to start Osphena due to side effects."

• Ray...
• June 25, 2015

For Endometriosis "Worst mistake of my life! I had one 3-month shot when I was 17, and I'm still regretting it (I'm 21 now). I was pretty much paralyzed while on it. I couldn't move on my own. I needed help to even sit up in bed. I missed so much school/work and cried almost all day, every day. I was in so much more pain. I was constantly sick (vomiting, nausea, painful bowel movements, headaches, joint pains), and the menopause symptoms were absolutely crazy. I still, to this day, have stomach issues I didn't have before. I have bone density loss as well. I will never recommend this drug to any woman. It is not meant for us."

• Kri...
• February 18, 2020

For Endometriosis "Ok y’all, I admit before taking Lupron Depot 11.25 mg, 3-month injection; I read every review I could find. I was disappointed to find mainly negative reviews, but I took a leap of faith and decided to get the injection anyway. Within the first month, I truly regret that decision. In tough situations, I typically look for the silver lining. However, I was not prepared for the extreme fatigue (no more 5 a.m. workouts), hot flashes all day, every day, night sweats that literally leave my side of the bed soaked (it’s totally gross), but the topper is body aching and hurting down to my muscles and bones like I have the flu... every day going on 63 days straight. I am 38 years old, in good shape, active when I started the injection. I was 115 lbs; I am now 130 lbs with no energy. Needless to say, I am declining the second treatment and look forward to 2-6 months when all of the side effects should fully wear off and hopefully get my normal life back."

• Tir...
• Taken for 1 to 6 months
• February 17, 2019

For Endometriosis "This made my pain much worse. It is the worst experience I've ever had with a medication! The side effects are much worse than the endo pain! This medicine shouldn't be given to women for endo! I have been in the worst pain and depression that I've ever had in my entire life thanks to this medication."

• Mar...
• March 25, 2020

For Uterine Fibroids "I feel the obligation to share my experience as it might help someone looking for some answers. I was prescribed this Lupron Depot shot prior to my second fibroid surgery with the intention of shrinking a large fibroid, as the first surgery was unsuccessful at removing the whole thing. I was bleeding significantly due to the fibroid, and the only benefit of having this shot was that it did stop my bleeding completely for 3 months. Other than that, I cannot ethically say anything positive about this shot. I started to have these large, painful cysts on my face that have yet to subside. It’s been 6 months since I got a 3-month dose shot, and my face is still covered in cysts. Ironically, this shot also made my fibroid grow bigger. It took an additional 2 attempts to remove the fibroid. The whole point of the shot was to shrink it so only 1 more attempt would be needed. Please do your research. This shot completely messed up my hormones."

• See...
• Taken for 1 to 6 months
• June 27, 2016

For Endometriosis "I would like to address women who already struggle with depression, insomnia, or mood disorders, like myself. If you're already bad off, don't do this to yourself, it might be the final 'push.' I got the 3-month shot (+add-back), and it made me suicidal. My moods went from extreme anger to sobbing, insomnia, hot flashes, and my left arm kept going numb in daily activities! This went on for a month, at 2 months, I leveled out. Not far into the 3rd month, the hot flashes came back, cold sweats (felt like drug withdrawal), and my pain was back! I went to my OB/GYN 1 week early because of this to find I had grown 11 new painful cysts! It didn't even work, and to stop it is also unpleasant (withdrawals). Worst med decision I ever made! HELL!"

• Ton...
• Taken for 1 to 2 years
• July 24, 2020

For Prostate Cancer "Taking Lupron injections for 7 months, out scheduled 18 months for prostate cancer. Experiencing common side effects like hot flashes, weight gain, reduction in size of testicles. Completed 28 treatments of radiation this past May. Taking injections in the buttocks every 3 months. Injections are not bad. A little soreness for a couple of days. The side effects are manageable so far."

• use...
• February 1, 2012

For Endometriosis "I was actually on Lupron Depot for 18 months. My periods stopped within a week, and my pain was gone within the first month. I almost didn't go on it because of the horror stories I read online, but I'm glad I did. My skin broke out more than normal, but nothing a little makeup couldn't hide. The hot flashes were intense at first, but slowly started to subside. After six months, they completely stopped. I also fully understand night sweats. The side effects were well worth it to me since I no longer have cramps that hurt so badly I pass out. I am also enjoying being period-free after never having a regular cycle and being anemic the better part of my life."

• Hol...
• Taken for 1 to 6 months
• September 16, 2018

For Uterine Fibroids "This shot did not shrink my fibroids in my uterus before my operation. As a matter of fact, they grew. It’s going on four months since I’ve had the shot, I already had my operation. I do still have my ovaries. I’m still getting hot flashes. I have a headache every day of different levels. The nausea almost went away. Hot flashes are worse at night, so I’m losing a lot of sleep. For the last three weeks, my legs have been aching every day when I get up. I have no desire to have sex. This is definitely miserable. My doctor said the effects of the Lupron would be gone in three months, but they’re still here. I don’t recommend the shot for anybody for any reason."

• duc...
• Taken for 6 months to 1 year
• July 11, 2021

For Prostate Cancer "I have been on Lupron for 6 months (2 of the three-month injections). This drug is very effective in slowing the prostate cancer growth. Testosterone is the fuel for PC. My testosterone level went from 840 to 11 in three weeks after my first injection! However, there surely are side effects. Mine are: 1. Fatigue and low energy with breathlessness upon exercise. 2. Hot flashes. 3. Low red blood cell count (anemia). 4. Lack of sexual desire and unable to perform. 5. Shrunken testicles and penis. The side effects are frustrating...but you can tough them out. God has given me strength, and without my faith...this would be much tougher. My wife has been an angel with her constant support. Good luck!"