Lupron Depot User Reviews & Ratings (Page 5)

• Mis...
• July 24, 2009

For Endometriosis "I took my first injection 4 days ago, but had a migraine that night. Since then, I have been crying a lot. I can't believe the side effects have hit me so fast. I have abdominal pain as well, but the crying is the worst so far."

• Swe...
• January 6, 2017

For Endometriosis "I was diagnosed with stage 1 endometriosis after I had a laparoscopy. My doctor suggested Lupron Depot for six months (2 shots). I have been on Lupron Depot for almost 3 months where it is time to get my second shot. I am almost sure I will not get the second shot. I am in worse pain than I was before the shot, and I have had NONSTOP bleeding. You are not supposed to be bleeding while on Lupron, especially for three months. I have an appointment with my doctor soon about my next step. The medicine is supposed to rid you of pain-but for me, it caused it to worsen. In regards to other side effects such as hot flashes, depression, mood swings, etc., I don't have any of that! Bottom line, I wish I never would have gotten this medicine."

• Anonymous
• Taken for less than 1 month
• October 20, 2012

For Endometriosis "I am only one week into the Lupron, and my pain has begun to not ease, but not be as sharp as it was at all times. I can finally breathe and think before the next stabbing pains begin. But about two days ago, I got mood swings. I seem insane, I'm fine, then I'm screaming. I'm only 17, and this is NOT what I need along with the disease. I hope it gets better, for I won't have any friends at the end of the six months."

• CDM...
• December 17, 2016

For Endometriosis "I suffer from terrible cramps and fibroids. I do take a low-dose birth control that sometimes barely helps my cramps. I was given the 1 dose a month, 6-month treatment after my GYNO could barely do a vaginal ultrasound for one of my visits, and I had been having a 'period' off and on for over 3 months. The fibroid was so large it obstructed the movement of the wand thingy. I've been on it for 5 months, the 1st month, I still got my awful period and spent my usual $50 on pads and Advil, just as heavy. But by the 2nd month, bye bye Aunt Flo, and it's been pretty okay except for the hot flashes, weight gain, tiredness, and the sore hips, soles, and ankles. The sore hips, soles, and ankles don't hit until the 4th month. The hot flashes just suck!"

• Ste...
• December 21, 2019

For Endometriosis "I have stage 4 endometriosis and adenomyosis. Had emergency surgery 3 years ago due to a large endometrioma causing a total blockage of my sigmoid colon. Everyone's reports on here about unbearable pain and severe bleeding-yup, same for me. I've been bleeding nonstop for over a year now. Received my first 1-month dose of Lupron on 11/22/19. The only side effect was a slight uptick in libido the first two weeks during the initial estrogen spike. The last week of the month, I got my period, but the bleeding and pain were much reduced from before. Noticed an improvement in pain during intercourse. I am on the add-back and have had no night sweats, hot flashes, or vaginal dryness. No impact on my mood that I could notice. Received my second dose, the 3-month long dose, yesterday (12/20/19). Can't comment yet on the experience, but I'm sure hoping to stop bleeding entirely and eliminate the pain."

• cra...
• June 10, 2015

For Endometriosis "I am very happy I went on Lupron Depot. I am on my 6th month of it, and although the symptoms of hot flashes, night sweats, moodiness, and some weight gain are not fun, it still is VERY worth it. I have been pain-free (when I was in debilitating pain before) and no period, which is nice. Hopefully, I'll be able to get pregnant soon too!"

• Kia...
• June 30, 2018

For Uterine Fibroids "My experience was horrible. My OB/GYN recommended Lupron for my fibroids. I have 1 large one the size of a grapefruit, 3 the size of tennis balls, and many pea-sized. Surgery was not an option. I get Lupron shots 1 time a month for 6 months. I had 13 acne cysts in total on my face that I had to have surgically removed (over time). I gained 30 pounds almost overnight, and it took me 3 years of intense dieting to get this weight off. My body thought I was going through menopause, so I had the hot flashes as well. I would not do it again. I spent a fortune only to find out after 6 months and all of this that the tumors were the same size. Years later, I am having health issues and wondering if related to Lupron usage."

• Alm...
• November 13, 2011

For Endometriosis "I have been receiving Lupron shots since August 2011. December will be shot number five. Within the first two weeks after receiving my first shot, I noticed a huge difference in pain. How awesome! I had been dealing with this pain since 2008. I had exploratory surgery and tried Chinese medicine along with acupuncture and found no relief. Lupron has been the first thing to help me be almost completely pain-free. Will post again after the 6th injection. I had one huge mood swing after my 1st shot and very little hot flashes. I am not craving chocolate as much but have found myself craving milk (I have always been a milk drinker)."

• Can...
• Taken for 1 to 6 months
• September 23, 2020

For Endometriosis "Lupron ruined my health. It made me depressed and have suicidal thoughts, which are not normal for me at all. I did not continue after month 4, and unfortunately, because I wanted to stop the medication, my doctor would not see me anymore. Please research the ingredients and side effects before you choose to take Lupron. My doctor told me specifically not to look up the side effects... Not wise!"

• Sic...
• Taken for 1 to 6 months
• September 24, 2020

For Uterine Fibroids "My experience with Lupron Depot has been challenging. I have side effects of memory loss, trouble breathing (did not have this before), heart palpitations just about every day (worst at night), nausea, extreme tiredness (daily). Periods had stopped before but started up when taking Lupron Depot (very light to spotting). I am in my second month of the 3-month injection, and I now have body aches and hot flashes every 15 minutes all day, which have subsided to every 30 minutes to an hour as I get close to wearing off. I will not know if the fibroid has shrunk until after the 3 months have passed. Not interested in sex, so do not want to be touched. Very sensitive since the shot and not having a taste for really anything. Feet swollen like Ms. Piggy. Would I get it again? Heck NO! I would stop eating red meat first and drink a healthy smoothie with raw veggies and fruit first."

• Sha...
• Taken for 6 months to 1 year
• September 20, 2019

For Endometriosis "I had severe endometriosis. I had the kind of pain that makes you blackout. I would bleed all over my chair at work. I wear only black or navy pants. So far, I've taken 3 shots, and thankfully I am pain-free. I have no period. But the hot flashes are HORRIBLE. I'm always hot and tired. I don't remember the last time I had a good night's sleep. I've gone as far as putting ice packs on my bed so that I can sleep for a few hours. I've gained about 35 pounds in 9 months, my hair is thinning, I ache all over, my vision has decreased so much, I seem to forget everything if I don't write it down. I think I got the entire list of side effects, however, that pain before taking Lupron? No way! I literally shake when I think about it. I'll try to manage."

• Anonymous
• March 18, 2010

For Endometriosis "I just had my 5th shot yesterday. The past few months have been painless in regard to side effects other than night sweats and mood swings. I have not gained any weight, and everything seems pretty normal. Once again, other than the mood swings. These are harsh, and sometimes I feel like another person has taken over my body and thoughts."

• Anonymous
• January 1, 2010

For Endometriosis "I did a 6-month treatment of Lupron, and it wasn't that bad. The first couple of months, I experienced migraines and hot flashes. For the remainder of the treatment, I continued to experience the hot flashes, but my mood swings became very uncomfortable for my family, friends, and me. I would one minute be calm and neutral...the next minute I would become mean and hateful. That was never how I was prior to the treatment. However, I completed my treatment in August 2009, and I haven't had any problems with my endometriosis at all. My doctor has now given me the option to either get pregnant or continue with birth control pills until I decide to become pregnant to maintain the endometriosis. I highly recommend this method if you can withstand the side effects."

• Anonymous
• January 22, 2009

For Endometriosis "I have taken monthly injections for the past 6 months. I had a very difficult time for the first 6 weeks of treatment, but since then have not had many side effects. I had severe stomach cramping initially, along with migraines and mood swings. As those side effects subsided, the hot flashes began. With the hot flashes came nausea and unpredictable crying fits. My doctor put me on a low dose of Estradiol and Prozac. Within a few days, I was pretty much back to my old self, minus the horrible belly pains. I have to say, overall the good outweighs the bad."

• KSt...
• September 25, 2022

For Uterine Fibroids "Do not be afraid of this drug. I am in my forties and have several fibroids. I was bleeding continuously for 8 months and needed a hysterectomy. My hemoglobin at the time was too low for a successful surgery, so my doctor suggested Lupron. It worked wonders. Bleeding stopped. Bloating went down. I'm sure my fibroids shrunk also. Hemoglobin recovered from a 6 to a 12 in just 4 months. Soon I will have my laparoscopic hysterectomy. Lupron saved me."

• End...
• August 26, 2015

For Endometriosis "Lupron is not for everyone! I must admit I was horrified to try it, but it came to a point I would rather die, so I had nothing to lose. In 2011 and 2012, both 9 months each. Then after treatment was birth control (Levora), high dose. Now, 2015, just started having severe pain uncontrolled by anything else, so started Lupron injection yesterday. This med made me forget I had the disease. I'm not saying there could be long-term issues or anything else. But right now, in this moment, I'm not sick, and every time before, it was a godsend. Hopeful this time will be as smooth as the last couple of times. Good luck."

• rub...
• Taken for 1 to 6 months
• July 11, 2018

For Uterine Fibroids "I had 8 tumors in my uterus, and the doctors told me there was no way to remove them. They gave me 2 shots of Lupron, and I started losing my memory, and the bleeding increased. I did a search for doctors that remove the tumors, and I found one. He took out the tumors, I was able to keep my uterus and have had no problems since. I thank God every day for this doctor! The only bad thing is, thanks to the drug, my memory is damaged for life."

• Doi...
• December 1, 2016

For Endometriosis "During my early 30s, I had 2 laparoscopies and 1 laparotomy for severe endometriosis but had no relief from pain. At 34, I had my 1st Lupron Depot shot. It eliminated my pain completely. The only side effects were hot flashes and irritability. The side effects were exactly what I am experiencing with menopause now at the age of 58. I did not have any joint pain or other side effects. After 6 months of shots, my primary care physician advised that bone loss could result from prolonged treatment, so we stopped treatment. As an alternative, I was put on low-dose birth control pills, which I took every day to stop my periods. Should have done this to begin with! No pain and no side effects!"

• Ei...
• December 7, 2016

For Endometriosis "I have endometriosis and adenomyosis, and pain was scary, and I became bedridden some of the days. I had my first Lupron 11.25 mg in June 2016. I am suffering following side effects, but I will continue this medication as pain from endo and adeno is worse than side effects. - Swelling at feet - Weight gain - 6 kg in 6 months - Increased sweating - Hot flash suffered only the first month of this treatment - Fluid retention - Carpal tunnel - Forgetful - Growth of upper lip hair - Slipped disc and compression of the right leg nerves. I am going to take the second injection soon, and after that, I will go for hysterectomy. Btw, I am just 36 :(."

• Anonymous
• November 8, 2009

For Endometriosis "I was very pleased with my Lupron experience. I was on a six-month course and found the first three to four months easy. I did experience hot flashes, mood swings, and slight insomnia. My fifth and sixth months were a little more difficult for me. The hot flashes became a little more apparent, the mood swings more frequent, and my face began to break out. To me, that was the worst. Along with the Lupron, I had a laparoscopy 2 months before the medication, and I started acupuncture treatments about a month before beginning Lupron, which really helped with the side effects. My pain levels before medication were unbearable. I could hardly bring myself to get out of bed. I now notice that my pain level is low if I have any at all."

• mom...
• Taken for 1 to 6 months
• June 18, 2015

For Endometriosis "I took the shot for 6 months. I had issues that I could tolerate, such as vision change. The injection would shoot pain across my lower back. Well, it's been 8 months since I had a shot. It took me 2 months before my period returned. I recently started experiencing pain in my belly button. Vision was getting worse, mood swings. The end of April, my period was bad, then 2 weeks later, I had another one. I was ready to have everything removed. I had given up hope of having a baby... So, out of the blue, I missed my period, and now I'm 5 weeks PREGNANT!! I wish everyone good luck and hang in there!"

• Sin...
• September 4, 2019

For Endometriosis "So I’ve been on Lupron Depot with an add-back for 10 months. I have severe endometriosis. I would bleed severely every month for at least two weeks, if not longer, with the worst pain of my life. I wanted to die. I definitely wasn’t living. The smallest movements, and I’d be soaked in blood. The pain was literally unbearable, and I’d have to make a trip to the emergency room. Yes, I do have side effects from the Lupron Depot: headaches, tired and drained, and for a few weeks out of my three-month cycle, my body hurts so bad I can barely walk around. But these side effects have nothing on the pain and depression I was suffering before. I had no life at all. Everything revolved around my period. It’s the only thing that’s given me relief."

• Ano...
• Taken for less than 1 month
• December 11, 2018

For Endometriosis "I received my first shot almost 2 weeks ago. I am on the 3-month dosage. Absolutely no side effects the first couple of days, but pelvic/abdominal pain began day 3. My period came as normal on day 12 of getting the shot. I was really hoping to not have any at all. I will gladly deal with the more common side effects if my pain and period will go away! Only a few bouts of nausea and moments where I’ll feel so sad. I’m 39, no kids, and have been suffering from debilitating, life-altering pain since 12! I’m praying this helps!"

• Men...
• November 20, 2015

For Endometriosis "This drug ruined my joints, chronic pain, I lost an inch in height, and my endometriosis was only gone for three years. I have gained 40 pounds, now have lost my mobility, can no longer dance or go out, I'm only 36, but I feel twice as old. I would never have taken it if I had known it was a chemotherapy drug for prostate cancer."

• Anonymous
• Taken for 6 months to 1 year
• February 7, 2016

For Endometriosis "I had a laparoscopy done in March 2015, and they determined stage 4 endometriosis. Before then, I had maybe 1 week out of a month without pain for over a year, it was horrible. My first injection was in September 2015. I had a laparotomy in October 2015, the doctor did an amazing job and removed all the scar tissue and cysts. My second injection was in December 2015, and the hot flashes are brutal. I am now on a low dose of estrogen to help with the hot flashes. It has helped but not fully. I highly recommend the injection if you want to be pain-free, the hot flashes are brutal but way better than the pain."