Trokendi XR Alternatives Compared
| Trokendi XR | Botox | Qulipta |
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| Trokendi XR (topiramate) | Botox (onabotulinumtoxinA) | Qulipta (atogepant) |
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Prescription only
Trokendi XR is an extended-release form of topiramate that may be used to reduce the frequency and duration of seizures or to prevent the development of migraine headaches. Paresthesias and... View more |
Prescription only
Botox is approved to treat many conditions, such as chronic migraine, involuntary muscle contractions or twitching, excessive sweating, increased saliva, and overactive bladder to name a few. Botox... View more |
Prescription only
Prescribed for Chronic Migraine, Migraine Prevention. Qulipta may also be used for purposes not listed in this medication guide. |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
Popular comparisons
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| More about Trokendi XR (topiramate) | More about Botox (onabotulinumtoxinA) | More about Qulipta (atogepant) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Trokendi XR has an average rating of 5.9 out of 10 from a total of 10 ratings on Drugs.com. 44% of reviewers reported a positive effect, while 44% reported a negative effect. |
Botox has an average rating of 5.6 out of 10 from a total of 456 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 43% reported a negative effect. |
Qulipta has an average rating of 7.3 out of 10 from a total of 93 ratings on Drugs.com. 62% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects | ||||||||||||||||||||||||||
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See also: Trokendi XR side effects in more detail. |
See also: Botox side effects in more detail. |
See also: Qulipta side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Trokendi XR prices and generic prices |
View all Botox prices |
View all Qulipta prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Other topiramate brands include: Eprontia, Qudexy XR, Topamax | Other onabotulinumtoxinA brands include: Botox Cosmetic |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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56 hours |
N/A |
11 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 285 drugs are known to interact with Trokendi XR:
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A total of 114 drugs are known to interact with Botox:
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A total of 173 drugs are known to interact with Qulipta:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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August 16, 2013 |
December 09, 1991 |
September 28, 2021 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.