Trazodone Alternatives Compared
| Trazodone | Ambien | Zolpidem |
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| Trazodone | Ambien zolpidem | Zolpidem |
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Trazodone is mostly used for its sleep-inducing effects (an off-label indication) rather than as an antidepressant. Only generic forms are available which makes it a lot cheaper than some other... View more |
Ambien induces sleep; however, Ambien CR, in particular, may impair physical and mental capabilities the next day. Ambien has also been associated with complex or dangerous sleep-related behaviors... View more |
Zolpidem induces sleep; however, longer-acting formulations may impair physical and mental capabilities the next day. May induce complex or dangerous sleep-related behaviors like "sleep-driving"... View more |
Choose a suggestion below |
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| More about Trazodone | More about Ambien (zolpidem) | More about Zolpidem | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Availability | ||||||||||||||||||||||||||
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Prescription only |
Prescription only |
Prescription only |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Trazodone has an average rating of 6.4 out of 10 from a total of 1321 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 30% reported a negative effect. |
Ambien has an average rating of 7.0 out of 10 from a total of 540 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 21% reported a negative effect. |
Zolpidem has an average rating of 6.9 out of 10 from a total of 991 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 23% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include: blurred vision, dizziness, drowsiness, headache, nausea, vomiting, xerostomia. See the full trazodone side effects document. |
Common side effects include: dizziness. See the full Ambien side effects document. |
Commonly reported side effects include: dizziness, drowsiness. See the full zolpidem side effects document. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all trazodone prices |
View all Ambien prices and generic prices |
View all zolpidem prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Desyrel, Desyrel Dividose | Other zolpidem brands include: Ambien CR, Edluar, Zolpimist | Ambien, Ambien CR, Edluar, Zolpimist | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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7.5 hours |
2.6 hours |
2.6 hours |
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| CSA Schedule** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
Category C
Risk cannot be ruled out
See the full Pregnancy Warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 605 drugs are known to interact with trazodone:
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A total of 430 drugs are known to interact with Ambien:
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A total of 430 drugs are known to interact with zolpidem:
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| First Approval Date | ||||||||||||||||||||||||||
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December 24, 1981 |
December 16, 1992 |
December 16, 1992 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.