Simvastatin Alternatives Compared
Simvastatin | Atorvastatin | Rosuvastatin |
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Simvastatin | Atorvastatin | Rosuvastatin |
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Prescription only
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain, particularly at higher dosages. Should not be used by people with active liver disease or in women planning a... View more |
Prescription only
Atorvastatin is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. Prescribed for High Cholesterol, High Cholesterol - Familial Heterozygous... View more |
Prescription only
Rosuvastatin is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. People of Asian descent may be more sensitive to the effects of rosuvastatin... View more |
Related suggestions High Cholesterol
Prevention of Cardiovascular Disease
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More about Simvastatin | More about Atorvastatin | More about Rosuvastatin | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Simvastatin has an average rating of 4.8 out of 10 from a total of 129 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 50% reported a negative effect. |
Atorvastatin has an average rating of 4.3 out of 10 from a total of 294 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 56% reported a negative effect. |
Rosuvastatin has an average rating of 5.0 out of 10 from a total of 255 ratings on Drugs.com. 36% of reviewers reported a positive effect, while 47% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: simvastatin side effects in more detail. |
See also: atorvastatin side effects in more detail. |
See also: rosuvastatin side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all simvastatin prices |
View all atorvastatin prices |
View all rosuvastatin prices |
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Dosage Forms Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
FloLipid, Zocor | Atorvaliq, Lipitor | Crestor | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
N/A |
14 hours |
19 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 317 drugs are known to interact with simvastatin:
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A total of 383 drugs are known to interact with atorvastatin:
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A total of 233 drugs are known to interact with rosuvastatin:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
December 23, 1991 |
December 17, 1996 |
August 12, 2003 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.