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Statins

Other names: HMG-CoA reductase inhibitors, statins

What are Statins?

HMG-CoA reductase inhibitors, also known as statins, selectively inhibit an enzyme called HMG-CoA reductase (3-hydroxy-3-methylglutaryl coenzyme A reductase) that is involved in the synthesis of mevalonate, a precursor of sterols including cholesterol. By inhibiting this enzyme, cholesterol and LDL-cholesterol production is decreased. Statins also increase the number of LDL receptors on liver cells, which enhances the uptake and breakdown of LDL-cholesterol. Most of the effects of statins occur in the liver.

Research has shown that elevated levels of total cholesterol, LDL-cholesterol, and apolipoprotein B are risk factors for developing cardiovascular disease.

Statins may be used in the treatment of hyperlipidemia (also called dyslipidemia or high cholesterol) and are most effective at lowering LDL-cholesterol.

List of Statins:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
Altocor
generic name: lovastatin
0 reviews
   
10
Altoprev (Pro)
generic name: lovastatin
2 reviews
   
9.5
Lescol (Pro)
generic name: fluvastatin
2 reviews
   
8.0
Mevacor (Pro)
generic name: lovastatin
3 reviews
   
7.5
Pravachol (Pro)
generic name: pravastatin
9 reviews
   
7.3
Crestor (Pro)
generic name: rosuvastatin
90 reviews
   
6.6
Lipitor (Pro)
generic name: atorvastatin
63 reviews
   
6.1
Livalo (Pro)
generic name: pitavastatin
57 reviews
   
5.7
Zocor (Pro)
generic name: simvastatin
20 reviews
   
5.4
Baycol
generic name: cerivastatin
0 reviewsAdd rating
FloLipid (Pro)
generic name: simvastatin
0 reviewsAdd rating
Lescol XL (Pro)
generic name: fluvastatin
0 reviewsAdd rating
Nikita
generic name: pitavastatin
0 reviewsAdd rating
Zypitamag (Pro)
generic name: pitavastatin
0 reviewsAdd rating

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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