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Statins

Other names: HMG-CoA reductase inhibitors, statins

What are Statins?

HMG-CoA reductase inhibitors, also known as statins, selectively inhibit an enzyme called HMG-CoA reductase (3-hydroxy-3-methylglutaryl coenzyme A reductase) that is involved in the synthesis of mevalonate, a precursor of sterols including cholesterol. By inhibiting this enzyme, cholesterol and LDL-cholesterol production is decreased. Statins also increase the number of LDL receptors on liver cells, which enhances the uptake and breakdown of LDL-cholesterol. Most of the effects of statins occur in the liver.

Research has shown that elevated levels of total cholesterol, LDL-cholesterol, and apolipoprotein B are risk factors for developing cardiovascular disease.

Statins may be used in the treatment of hyperlipidemia (also called dyslipidemia or high cholesterol) and are most effective at lowering LDL-cholesterol.

List of Statins:

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Drug NameView by: Brand | Generic Reviews Avg. Ratings
Altocor (More...)
generic name: lovastatin
0 reviews
   
10
Altoprev (Pro, More...)
generic name: lovastatin
2 reviews
   
9.5
Lescol (Pro, More...)
generic name: fluvastatin
2 reviews
   
8.0
Mevacor (Pro, More...)
generic name: lovastatin
3 reviews
   
7.5
Pravachol (Pro, More...)
generic name: pravastatin
7 reviews
   
7.4
Crestor (Pro, More...)
generic name: rosuvastatin
89 reviews
   
6.6
Lipitor (Pro, More...)
generic name: atorvastatin
58 reviews
   
6.1
Livalo (Pro, More...)
generic name: pitavastatin
55 reviews
   
5.9
Zocor (Pro, More...)
generic name: simvastatin
20 reviews
   
5.4
Baycol (More...)
generic name: cerivastatin
0 reviewsAdd rating
FloLipid (Pro, More...)
generic name: simvastatin
0 reviewsAdd rating
Lescol XL (Pro, More...)
generic name: fluvastatin
0 reviewsAdd rating
Nikita (More...)
generic name: pitavastatin
0 reviewsAdd rating
Zypitamag (Pro, More...)
generic name: pitavastatin
0 reviewsAdd rating
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