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Lescol XL

Generic Name: fluvastatin (FLOO va sta tin)
Brand Name: Lescol, Lescol XL

What is Lescol XL?

Lescol XL is in a group of drugs called HMG CoA reductase inhibitors, or "statins." This medicine reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).

Lescol XL is used to lower cholesterol and triglycerides (types of fat) in the blood and to slow the build-up of plaque (fatty deposits) in your blood vessels.

Lescol XL is also used to lower the risk of heart complications in certain people with coronary artery disease.

Lescol XL is used in adults and children who are at least 10 years old.

Lescol XL may also be used for purposes not listed in this medication guide.

Important Information

This medicine can harm an unborn baby or cause birth defects. Do not use Lescol XL if you are pregnant.

You should not take Lescol XL if you have liver disease, or if you are breast-feeding a baby.

Some medicines can cause unwanted or dangerous effects when used with Lescol XL. Tell your doctor about all other medicines you use.

Before taking this medicine

You should not take Lescol XL if you are allergic to it, or if:

  • you have active liver disease; or

  • you are pregnant or breast-feeding.

To make sure Lescol XL is safe for you, tell your doctor if you have:

  • a history of liver disease;

  • muscle pain or weakness;

  • kidney disease;

  • diabetes;

  • a thyroid disorder; or

  • if you drink more than 2 alcoholic beverages daily.

Lescol XL can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).

The following drugs can increase your risk of serious muscle problems if you take them together with Lescol XL:

Lescol XL can harm an unborn baby or cause birth defects. Do not take this medicine if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Use effective birth control to prevent pregnancy while you are taking this medicine.

Fluvastatin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking fluvastatin.

Lescol XL is not approved for use by anyone younger than 10 years old.

How should I take Lescol XL?

Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take this medicine with a full glass of water.

Lescol XL is usually taken once or twice daily, with or without food. Take the medicine at the same time each day.

Do not crush, chew, or break an extended-release tablet. Swallow it whole. Tell your doctor if you have trouble swallowing the pill.

While using Lescol XL, you may need frequent blood tests.

It may take up to 4 weeks before your cholesterol levels improve. Keep using this medicine as directed, even if you feel well. High cholesterol usually has no symptoms.

Lescol XL is only part of a complete treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If you are more than 12 hours late, skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Lescol XL?

Avoid eating foods that are high in fat or cholesterol. Lescol XL will not be as effective in lowering your cholesterol if you do not follow a cholesterol lowering diet plan.

Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.

Lescol XL side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

In rare cases, Lescol XL can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, or dark colored urine.

Also call your doctor at once if you have:

  • signs of a kidney problem--little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; or

  • liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

What other drugs will affect Lescol XL?

Many other drugs can increase your risk of muscle problems if you take them with Lescol XL. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with this medicine. Give a list of all your medicines to any healthcare provider who treats you.

Where can I get more information?

  • Your pharmacist can provide more information about Lescol XL.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 12.01.

Date modified: January 03, 2018
Last reviewed: March 22, 2016

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