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Colesevelam User Reviews & Ratings

Brand names: Welchol

Colesevelam has an average rating of 8.5 out of 10 from a total of 114 reviews on Drugs.com. 79% of reviewers reported a positive experience, while 8% reported a negative experience.

Reviews for Colesevelam

  • Tin...
  • October 22, 2014

Welchol (colesevelam) for Diarrhea, Chronic "After 41 years of horrible pain, diarrhea and incontinence, I met a GI Dr. who ordered Welchol. I thought he was nuts. Within 4 days, I was normal. I would willingly mortgage my house to pay for this medicine. Max dose 6/day. I now have a life. It's so nice not to be told I was nuts, nervous, anxious, need a shrink, and all the other crap I listened to for 41 years. I have been fine for almost 6 years with only 2 one-day relapses. My gallbladder is fine. I am one happy camper. True story, folks."

10 / 10
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270 Report
  • wezzie
  • Taken for 1 to 6 months
  • January 27, 2014

Welchol (colesevelam) for Diarrhea, Chronic "I have had severe diarrhea for years after getting gall bladder removed. Had many tests run, tried everything. Eat, bathroom, eat, bathroom I was miserable. I signed up for medication study program after trying many different studies a wonderful caring nurse who led the studies suggested this medicine. WOW, I'm living again. I was spending a large amount of my life in the ladies room now I'm regular. They prescribed me three pills a day it caused constipation. One a day every morning keeps me regular. What a lifesaver, I was miserable."

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222 Report
  • Anonymous
  • August 19, 2013

Welchol (colesevelam) for Diarrhea, Chronic "Diagnosed at 18, went on until 28. I had a miserable existence for 10 years. 5 minutes after eating, I better be near a toilet. Gastroenterologists tested and tried so many different things with no success. Told my GI I was having a substantially lower quality of life with this problem. He prescribed me Welchol. The next day, I enjoyed my first meal in years and cried. Truly was a miracle pill for me."

10 / 10
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211 Report
  • what...
  • January 31, 2014

Welchol (colesevelam) for Diarrhea, Chronic "I had my gallbladder removed in 2011. I was planning my life around a restroom, and it was affecting my social life. I would not go on trips and did not want to go to anyone's house to eat for fear of an episode. Welchol has been a miracle for me. I only take them as I need them, sometimes even 1 or 2 a week. It is very expensive, so I'm glad I don't have to take them every day."

10 / 10
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176 Report
  • luv_t...
  • April 18, 2012

Welchol (colesevelam) for Diarrhea, Chronic "I have a similar experience to other reviewers. I had my gallbladder removed in 2002, and have had irritable bowel syndrome for 15 years, with each year it seems to get worse. I couldn't tolerate spending 1/2 my day in the bathroom. It was so awful that I looked for where the bathroom was at a restaurant before I ordered, just so I knew where to go when the meal was done. When the stomach cramps and the 'oh poop, I gotta poop' feeling came on, by the 2nd day of taking Welchol, it started working for me. I only went to the bathroom once the entire day! For me, that was a miracle. I still try not to eat trigger foods or drink coffee (I LOVE coffee, but my stomach thinks otherwise) but at least I can live a normal life again, something I had forgotten about."

10 / 10
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196 Report

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  • Hubie
  • Taken for 5 to 10 years
  • May 11, 2024

For Diarrhea, Chronic "Colesevelam gave me my life back. I was diagnosed with a low-functioning gallbladder with sludge, and it was recommended that I have it removed. After surgery, I was left with chronic severe diarrhea that made it difficult to leave the house until the morning purge was over. I finally made an appointment with a gastroenterologist, and after trying a few things that didn't help, she recommended I try colesevelam. It took a little bit to get the dosage adjusted to get it to work best with my needs, but I can live a pretty normal life now. I take 2-3 tablets twice daily. I also read about adding Metamucil fiber capsules along with the colesevelam, which seemed to help even more. Fiber balances the liquid in the gut. I take 3 capsules 3x daily with food, but it needs to be added very gradually. Colesevelam needs to be taken with food and NOT just before lying down. Also, generics vary greatly. Zydus was worthless! Amneal is good. Cosette the best."

10 / 10
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2 Report
  • Swamp...
  • Taken for less than 1 month
  • May 31, 2013

Welchol (colesevelam) for Diarrhea, Chronic "2 days before Christmas I came down with diarrhea and it continued to get worse. Many trips to the Drs and hospital and finally after 4 months was sent to a Specialist. He put me on 6 pills a day, 625 mg Welchol. I had gone from a size 20 to a size 12, no energy, headaches, pains and shakes (from diarrhea). This medication has worked wonders for me. I am so happy that I don't have to look for the nearest bathroom and stay close to it any longer. I have had no side effects either. I have gained 2 pounds too. I take all 6 pills at one time about 4 hours after my morning medicines. Welchol works wonders for me."

10 / 10
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159 Report
  • user
  • Taken for 1 to 6 months
  • August 30, 2020

For Diarrhea, Chronic "Thanks to everyone for sharing. After reading these reviews I asked my doctor if could try colesevelam for my chronic diarrhea. I've had IBS-D for over 10 years, it got really bad these last 4 years, I've tried everything and nothing helped until this. Been taking Colesevelam for 32 days and not one case of diarrhea - not one! It's a bit constipating so I'm reducing the dosage, I've read between 2 and 6 tablets per day is best. I'm doing 3 per day for the last week and will now go down to 2. Can't tell you how much this has changed my life! no side effects either."

10 / 10
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63 Report
  • welcol...
  • Taken for 5 to 10 years
  • July 4, 2012

Welchol (colesevelam) for Diarrhea, Chronic "Had my gallbladder taken out, got chronic diarreha immediately even by just sipping water. I started off with 2 pills 3x a day, then got too constipated then was able to keep lowering the dose until one pill works for everyday use, but no greasy foods for me. Thanks to Welchol, I can enjoy life again and not live it in the bathroom."

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148 Report
  • strega
  • February 1, 2016

Welchol (colesevelam) for High Cholesterol "I had my gallbladder removed in 2002 and have been dealing with IBS after eating for 14 years and thought I had to just live with it as a consequence of surgery! I have had high cholesterol for years, so my primary care physician prescribed this drug. It stopped my IBS and will lower my cholesterol, it also helps with my hypoglycemia. win,win,win.... im 57 and before using this drug I wasn't enjoying life much worried about toilets and heart disease or expecting to live a long full life. Now 3 less thing's to worry about : )"

10 / 10
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111 Report
  • Anonymous
  • December 11, 2019

For Diarrhea, Chronic "I have chronic Crohns disease and had my gallbladder out 9 years ago. I always had diarrhea but after gallbladder removal it got so bad I couldn't leave the house. I stopped seeing friends and going out socially as I always needed the toilet. After 8 years of painful stomach cramps and constant diarrhea A consultant at the hospital mentioned bile acid malabsortion. I take one tablet 3 times a day with food. This medication has changed my life I feel normal again after being in agony and needing the loo literally 10 times a day. I had my first holiday in 10 years this summer. This medication has given me my life back!!!"

10 / 10
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68 Report
  • bob
  • January 10, 2020

For Diarrhea, Chronic "I am 11 years post gall bladder removal. Spent the first 6 mths after surgery running to bathrooms. Made leaving the house or office impossible. If you're reading this, you probably know. Doc prescribed Welchol/coleselevam - literally changed my life. Here is what I have learned - hope it helps: 1) You MUST take this with real food (significant meal) or it is much less effective. 2) Don't take before you lay down - really bad heartburn 3) play with dosage until you get the right amount and frequency - I take two with breakfast and I'm good. When I travel or expect to not eat on regular schedule I usually add 1 tablet with each meal plus 2 with first meal of the day. 4) This is expensive - even with insurance - using coupon sites like goodrx, WebMD, etc can sometimes get you a good deal 5) Suggest you get max dosage on your Rx (3 tabs, 2X daily) - allows you to get the most bang for your buck if you find a good price. I can't imagine what it would be like without this medication."

10 / 10
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  • Nanny...
  • November 7, 2008

Welchol (colesevelam) for Diarrhea, Chronic "I have had diarrhea every morning with pain. After reading about gall bladder removal I found that some try Welchol to help because it is a bile sequestor. It works great for me. I went to a gastroenterologist and told him about my findings and he said "Congratulations" you diagnosed yourself. He gave me a years prescription for Welchol. I take three in the morning and am doing quite well. Wish I had known about this several years ago. Before Welchol I could barely leave my home before noon. Now I can travel again. So far, no side effects. Thank Goodness."

10 / 10
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158 Report
  • Lazyf...
  • Taken for 1 to 6 months
  • February 17, 2020

For Diarrhea, Chronic "I've been on colesevelam 625mg for two months now I take 6 a day along with 6 loperamide an 6 codeine I have some good days but mostly bad days - I don't go out, I can't work, I don't talk to my friends any more, diarrhoea has ruined my life. I'm 30 and I have suffered with this since I was 20 I honestly don't know what to do anymore. I have been tested for everything and the tests always come back clear which is so frustrating If I won the lottery I would give every penny away if someone could find a cure for me I want my life back I feel so alone it would be so nice just to chat to someone who is going through the same thing as me"

5 / 10
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59 Report
  • BPoppe
  • Taken for 6 months to 1 year
  • August 24, 2013

Welchol (colesevelam) for Diarrhea, Chronic "Gall bladder was removed in 1994. Ever since then severe diarrhea has been mostly on sometimes off. Many meds later and after seeing GI specialist my primary care physician prescribed Welchol. Great results! I take 6 pills in a divided dose. I still take 1 anti-diarrheal and 'everything' is better now."

10 / 10
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110 Report
  • LBano
  • Taken for 1 to 2 years
  • February 2, 2020

For Diarrhea, Chronic "I had my gallbladder removed 2 years ago and suffered from diarrhea and cramping after every meal afterwards. I couldn't go out to eat at restaurants, go on trips, or leave the house unless I knew that a bathroom was close by. I finally got fed up with it and saw my doctor about it. He prescribed Colesevelam and it changed my life. I only take 1 pill a day and I experience no side effects from it, other than occasional constipation. I love it because it allows me to eat whatever I want without ending up in the bathroom afterwards."

10 / 10
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53 Report
  • snookie
  • April 16, 2012

Welchol (colesevelam) for Diarrhea, Chronic "I got my gallbladder removed a little over 2 years ago. I could not eat anything. Most drinks would even make me sick. I have seen several doctors, but the GI doctor gave me Welchol and I take two 625mg pills twice a day with food. I no longer have to watch what I eat. I have been prescribed several meds prior to Welchol, but nothing helped. 4 pills sounds like a lot, but if needed I can even take 6 pills per day. I never have to take more than 4 though. Ask your doctor for these. You will not be sorry!"

10 / 10
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109 Report
  • Anonymous
  • January 8, 2009

Welchol (colesevelam) for Diarrhea, Chronic "I spent two years with chronic diarrhea. After I had major surgery, the surgeon noted that my gall bladder was very scarred. When my general practitioner saw this, he suggested I might be suffering what he called "chronic dump" (leaking gall bladder) which might be causing my...well, chronic dump! He gave me a prescription for Welchol (1 per day). He said that it was a low dosage of the drug and I shouldn't have any problem with side effects (I do take all my daily vitamins and supplements about 4 hours after the Welchol for absorption reasons). Not only has this drug worked wonders for me, I only take it as needed."

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  • Colle...
  • September 23, 2010

Welchol (colesevelam) for Diarrhea, Chronic "After I had my gallbladder out, I had bile salts diarrhea - the as-soon-as-you-eat-your-body-fire hoses-it-out sort. Very uncomfortable, and I lost about 40 pounds before my doctor finally prescribed Welchol. I take one at breakfast and one with dinner (just before the meal - not hours, which is very handy), and it has worked miracles. Highly recommend talking to your doctor if after your gallbladder surgery you're trying to live on dry toast."

9 / 10
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111 Report
  • linda
  • Taken for 1 to 6 months
  • January 8, 2020

For Diarrhea, Chronic "Suffered IBS with chronic diarrhea for many years, had many days off work and many late starts due to mornings being the worst for me. I came across this site and asked my doctor if I could try these as I also have high cholesterol and cannot tolerate satins. I take 2 tablets before bed and I have never had any diarrhea issues since, no diarrhea at all any more - my life has changed so much and I feel I can go places without having to worry about having accidents. I no longer take any immodium at all."

10 / 10
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  • txrere
  • February 1, 2018

For Diarrhea, Chronic "I've suffered from chronic diarrhea for over 10 years. I've been to dozens of doctors, taken more tests than I care to remember, and been told at the end of every visit that they can't figure out why it's happening to me or how to stop it. I've been living on daily max doses of Imodium for years. This year, during a consult for a regular colonoscopy , my new gastroenterologist recommended I try Welchol, a cholesterol drug that he thought might help. It's been the best three months of my life! I started the drugs the day of the colonoscopy. I went 24 hours with no symptoms. I thought it was because of the cleanse from the procedure. But it's been three months and NO DIARRHEA. I eat what I want, I no longer scope out the bathroom when I go out. I'm finally leading a normal life without chronic diarrhea. This is a miracle drug to me, and my only question is why didn't the dozens of other doctors recommend it sooner!"

10 / 10
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58 Report
  • Kate
  • Taken for less than 1 month
  • May 3, 2019

For Diarrhea, Chronic "I developed IBS-D about 7 years ago. I had accidents at my workplace, and in the car heading to work. (Almost always in the morning.) I have tried a number of things and nothing helped more than a day or so. My doc finally prescribed colsevelam for the uncontrollable bowel motions to me just a couple weeks ago. I have been taking it for just 10 days, and while I have had some very good days, I have had some huge relapses. I am curious how long it takes to work for most people, and whether it is better to take at morning or before bed. Also, do you all take with a meal or not? My doctor prescribed three tabs (huge) once a day, and I have been taking in the morning. Interested in all tips from actual users. The good days have been amazing and if I can get all or mostly all good days, I would rate this a 10!! Until I know for sure, the rating is just in the middle."

6 / 10
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48 Report
  • Anonymous
  • May 7, 2010

Welchol (colesevelam) for Diarrhea, Chronic "Did not need to take full dose of six tablets daily - only one tablet each morning and years of "dumping" syndrome following meals has completely stopped! Fabulous, unexpected results.......love my GI doctor for prescribing this medicine!"

10 / 10
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98 Report
  • Anonymous
  • November 21, 2011

Welchol (colesevelam) for Diarrhea, Chronic "I had diarrhea for a year and a half following gall bladder removal. I am so grateful to be able to eat without running to the bathroom within ten minutes. The day after I began taking Welchol, I won a dualthlon, probably because I didn't need to use the restroom and I ate a decent breakfast. Thanks for giving me my life back!"

10 / 10
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89 Report
  • Jack
  • September 25, 2013

Welchol (colesevelam) for High Cholesterol "Five months ago my total cholesterol was 281 (LDL was 199). I can't tolerate statins so my doctor suggested Welchol. I started eating a plant-based diet (no meat or dairy) and began going for walks in the morning. Yesterday my latest blood test showed that my total cholesterol is now 193 and my LDL is 125. That's the first time in 15 years that my cholesterol has been under 200. The diet and exercise certainly had an impact and I'm sure Welchol pushed the numbers even lower."

9 / 10
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77 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.