Colesevelam Alternatives Compared
| Colesevelam | Repatha (evolocumab) | Leqvio (inclisiran) |
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| Colesevelam | Repatha (evolocumab) | Leqvio (inclisiran) |
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Prescription only
Prescribed for Diarrhea - Chronic, Hyperlipoproteinemia Type IIa - Elevated LDL, Type 2 Diabetes, High Cholesterol, Hyperlipoproteinemia. Colesevelam may also be used for purposes not listed in this... View more |
Prescription only
Repatha is a PCSK9 inhibitor that may be used to reduce LDL-C levels in people with primary hyperlipidemia and HoFH, and also to reduce the risk of cardiovascular events in adults with established... View more |
Prescription only
Prescribed for High Cholesterol - Familial Heterozygous, High Cholesterol. Leqvio may also be used for purposes not listed in this medication guide. |
Related suggestions High Cholesterol
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| More about Colesevelam | More about Repatha (evolocumab) | More about Leqvio (inclisiran) | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Colesevelam has an average rating of 8.6 out of 10 from a total of 124 ratings on Drugs.com. 79% of reviewers reported a positive effect, while 6% reported a negative effect. |
Repatha has an average rating of 5.3 out of 10 from a total of 689 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 45% reported a negative effect. |
Leqvio has an average rating of 7.2 out of 10 from a total of 82 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 5% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Colesevelam side effects |
View all Repatha side effects |
View all Leqvio side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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N/A |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Repatha prices |
View all Leqvio prices |
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| Dosage Forms | ||||||||||||||||||
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N/A |
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| Brand Names | ||||||||||||||||||
| Welchol |
N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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N/A |
408 hours |
9 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 93 drugs are known to interact with Colesevelam:
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A total of 2 drugs are known to interact with Repatha:
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No known drug interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||
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May 26, 2000 |
August 27, 2015 |
N/A |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.