Leqvio and Joint Pain: What Users Say

• Sue...
• Taken for 1 to 6 months
• May 17, 2023

For High Cholesterol, Familial Heterozygous "I have had my first and second doses of Leqvio, and unfortunately, I am having a lot of muscle and joint pain - primarily in my back, neck, and shoulders. It is quite similar to the pain I was having from taking statins, so not sure why that is. It has definitely improved my cholesterol numbers, which is a plus."

• Jay...
• Taken for 1 to 6 months
• September 5, 2024

For High Cholesterol "Painful joints when moving around after sitting. Troublesome cough. Feeling nauseous frequently, especially in the morning before breakfast. Night cramps every night disturbing sleep, and therefore causing tiredness the next day. Extreme fatigue during the day needing an afternoon nap."

• MJ ...
• Taken for less than 1 month
• February 6, 2025

For High Cholesterol "The drug does work to lower LDL, but for me, the side effects aren’t worth the risk. I experienced the following: The injection pain lasted 20 min, but very painful! Severe shoulder pain 2 days after injection, lasted 2 days. Some joint pain, slight, but irritating cough ever since the first week. I had a very, very painful blood clot in my leg that lasted 2 weeks. My eyes became somewhat red, like they were bleeding. It was scary. The biggest factor for me was a big jump in my glucose fasting level. I knew this because I had blood work a week before the injection. I had blood work again 2 weeks after the shot. I’m not going to continue taking the drug. I’m eating clean, and I’ll take my chances. I don’t want to exchange one problem for numerous others."

• Sou...
• Taken for less than 1 month
• June 4, 2024

For High Cholesterol, Familial Heterozygous "This is in regards to side effects of Leqvio. Had the first injection about five days ago. No pain or redness at the injection site. A bit of soreness at the injection site for about 24 hours. A lethargic feeling off and on since the injection. A small amount of muscle or joint pain in the first 72 hours after the injection. No diarrhea as yet. Slightly loose BMs. No fever. Have experienced periods of being 'light-headed', i.e. feeling faint. Have not communicated this to my physician yet. Will do so later this week. I am hopeful this injectable medication will lower my LDL and thus, my total cholesterol number."

• Sta...
• Taken for 6 months to 1 year
• March 14, 2024

For High Cholesterol, Familial Heterozygous "I could not take statins without side effects. Sore muscles, aching joints. I was crying at night, could not sleep. After using Leqvio for 2 doses, I don't even need to take any statins. I also changed the way I eat."

• rog...
• Taken for 6 months to 1 year
• May 19, 2024

For High Cholesterol "Not sure if this is related to Leqvio or not, however, since beginning the Leqvio regimen I have experienced an increased level of muscle and joint pain and reduced mobility."

• Jay...
• Taken for 1 to 6 months
• September 5, 2024

For High Cholesterol "Painful joints when moving around after sitting. Troublesome cough. Feeling nauseous frequently, especially in the morning before breakfast."