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Repatha User Reviews & Ratings

Repatha has an average rating of 5.0 out of 10 from a total of 586 reviews on Drugs.com. 38% of reviewers reported a positive experience, while 51% reported a negative experience.

Reviews for Repatha

  • satin
  • July 4, 2021

For High Cholesterol "First, let me say that my cholesterol has been creeping up over the years to mid 200's, since I was pregnant in my 30's. I am now in my 70's. In the last 3 years, I tried to inject Repatha. In the first year, I injected five times in five months, and my cholesterol plummeted down to 160, but I felt weak. More recently, I had one injection in September and another in December. The injection in December turned me into a cripple. I went to see a few doctors who prescribed Prednisone to get me over the intense pain in my hip joints. It is now 4th of July weekend, 2021. In SIX months time, I am ALMOST back to normal. It still hurts to pick things up off the floor, and to bend down to put on my shoes. Also, any twisting motion of my lower body hurts. I think that Repatha should be taken off the market. I wish that we could band together and file a class-action suit against Amgen. Thank you for reading this."

1 / 10
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  • lynchie
  • Taken for 6 months to 1 year
  • May 18, 2021

For High Cholesterol "I started taking Repatha last July. I had been previously taking Itorvastin. I had side effects especially muscle pain and joint pain. I had been stopped for about 5 months. My current cardiologist said I should try Repatha due to the low number of reported side effects. During second months injections (every two weeks) I felt mild muscle pain and weakness. I took tylenol to help with the pain. It has become progressively more insidious. Yesterday 5 days from last injection I could not get out a chair, running nose, trouble walking, can't go up and down stairs, severe pain in ankles, knees, hips and back. loss of upper body strength, itching. A year ago I could carry two 40 bags of wood pellets up two flights of stairs. Now I can't lift a bag off the ground. Advised cardiologist office. I was no longer ever going to take Repatha. Havent' heard a word in 5 days. My advice, if you try Repatha call a half because side effects may get progressively worse."

1 / 10
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  • Horse...
  • Taken for 1 to 6 months
  • September 4, 2020

For High Cholesterol "I’ve taken 7 doses of Repatha. I have been experiencing extreme weakness and pain over all of my body. I have a pacemaker due to a heart condition and very high cholesterol. My dr felt this wonder drug would help! We’ll all this drug has done is ruin my zest for life!! I’m totally exhausted all the time my vision has become very blurred. Just doing normal daily activities has become very burdensome!!! It has drastically effected my quality of life!! I almost called 911 three days ago as I honestly felt my life was slipping away. I couldn’t stand couldn’t function!! It took 2 hrs before I was able to walk without feeling like my legs were rubber!!! This is THE worst medicine ever!!! If you have the choice DO NOT take this drug!! I wish I had done my homework BEFORE considering this drug!!"

1 / 10
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Frequently asked questions

  • HopeT...
  • April 6, 2021

For High Cholesterol "My husband just took his 3rd dose last Thursday. He was having trouble with statins at high doses since having a stroke. The stroke happened in a hernia surgery, we think! Anyway, he does have high blood pressure and cholesterol since age 18 (family thing). He decided to give this injection a try. He said tonight that he felt his legs and body were like rubber. His muscles are achy to which this drug was not supposed to do. He said he was going to stop the injections. After reading these reviews, I know it’s this drug too!! Why is this still on the market?? Someone? Anyone? His quality of life was diminishing with each statin!! Why are the drs still prescribing it? Thank you to those that wrote reviews. I hope everyone starts feeling better soon!! It sounds as though it will take a while to get these meds out of his system"

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  • Scott
  • April 30, 2020

For High Cholesterol "3 months after starting Repatha, I had my first two (ever) panic attacks within a week. I felt as though I was constantly on the verge of another panic attack, the anxiety wouldn't leave me, and I was experiencing bizarre thoughts. I had to see an Urgent Care physician to get medicine that would help get me under control. I was prescribed anti-depressants which did little to nothing to help. The next month, I began to suspect the Repatha and stopped taking it and the anti-depressants. I have been off of it for two months. I still have days of depression and anxiety for no reason, but I feel somewhat better, and hope that eventually I can return to my normal happy self. Repatha is extremely dangerous in my opinion and I would not recommend it to my worst enemy. I am extremely allergic to all statins, so I have no choice but to do my best to control my cholesterol with diet and exercise. I'd rather die early of heart related issues than to ever try Repatha again, it's pure poison."

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Are you taking this medicine?

  • Pondoak
  • Taken for 1 to 6 months
  • August 25, 2020

For High Cholesterol "I have previously been unable to take any cholesterol medicine, because it bothered my muscles. I have tried five different kinds of cholesterol medication. My doctor was finally able to get my insurance to cover the Repatha. I have taken three doses, so a month and a half. My muscles started to feel tight in both legs and then a weakness on one side. I had a CK blood test week ago and instead of 14 it was 936! Since nothing has changed besides the Repatha, my doctor told me to stop taking it. This is truly a frightening scenario since Rapatha is being sold as a medication that does not affect your muscles!"

1 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • February 25, 2020

For High Cholesterol "So 1 out of 1000 users of Repatha have no issues. For others who are suffering start calling attorneys call and report to FDA. Best of all hopefully someone calls 60 minutes to do a story. Enough is enough. This is heartbreaking what Repatha is causing all these side effects and they know it It’s all about money"

10 / 10
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More FAQ

  • Robbie
  • Taken for less than 1 month
  • May 7, 2021

For High Cholesterol "I have been on numerous cholesterol lowering Statins for over twenty years. First Liptor, then Cresto and then Repatha. Liptor caused me to have very painful problems and cramping in my ankles and achilles tendons so I switched to Crestor. I was on Crestor for quite a few years without many problems that I could see but I did manage to tear both my biceps and had to repair both surgically. My neck pain was out of control while on the Crestor and I consulted a Neurosurgeon who fused me between C 6-7 in my neck. After that surgery I have been unable to take anything for my cholesterol. In July of 2020 I was diagnosed with AFib and sent to a Cardiologist who did blood wanted me to try Repatha. I tried it and within a few days the neck pain was considerably unbearable. Also I was short of breath quite substantially. I don't know about the Statin drugs or Repatha. They both don't agree with me at all. Guess I'll have to take my chances"

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  • Gfiffy
  • March 3, 2020

For High Cholesterol "12/12/19 first Repatha injection taken at 1:30 pm. (4 years post renal transplant) Doc assured my it would be no problem. Sitting watching TV at 9 pm broke out in sweat had the feeling of cold water running through my sinus cavity one side only. Rapid heartbeat, blood pressure spiked, cramps in calves and back of thighs for several nights. Major flu like symptoms off and on since injection. Visits to neurologist, cardiologist, and general all say can last for quite a while half life ranges from 11 to 17 days so for most of it to clear my body could be up to 93 days. Now having esophaguses and stomach problems. Never had this before. I believe that not many Trial tests were on taking repatha with anti-rejection Meds. But from my experience they don’t blend well with Repatha. Still feeling like rubbish have a good day or two and then it’s back just don’t have a consistent feeling of well being. 81 days out. Has anyone fully recovered and if so how long did it take. I’m a 58 year old male."

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  • Valerie
  • Taken for 1 to 6 months
  • March 5, 2023

For High Cholesterol, Familial Homozygous "I am one of the unlucky individuals who react negatively to statins with elevated liver enzymes, so my cardiologist prescribed Repatha. After jumping through hoops to get it approved by my insurance, I took the first shot. I had some back pain after the first shot but it quickly went away and I was excited that I didn’t seem to have any of the side effects that others spoke up about. After my second shot, I began to experience pain in my toes and feet the next day. It feels like my toes are frozen and burning simultaneously. It’s like I have frostbite on my toes and feet with constant pain. It’s not pins and needles, but I guess it’s considered peripheral neuropathy. I’ve been taking Tylenol to minimize the pain but it never goes away. My doctor says it’s not a side effect of the drug, but there’s no other reason for this pain to have appeared the day after my second shot. I will be stopping this medication ASAP."

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  • Woody
  • Taken for 2 to 5 years
  • February 29, 2020

For High Cholesterol "I had a heart attack in late 2004 and double bypass in early 2005 at 42. I can't tolerate statin drugs so my doctor said there was a great new drug out there called Repatha. It was a miracle drug so I started taking it. After about two years I started having lots of muscle pain, cramps and severe headaches. Five months ago I had a stroke. At the time I thought I was having a migraine. My doctor took several MRI's, X Ray's and cat scans but could not determine what caused the stroke. I suspect that Repatha was the cause. If you are on Repatha please stop taking it right now. It is not worth it. This drug should be taken off the market fast before someone dies. I could have, but was very lucky."

3 / 10
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  • KarKar
  • January 28, 2020

For High Cholesterol "I've been off of repatha for almost 2 years. I still have extreme muscle weakness in my legs. I fear this may be permanent. This is the worst drug on the market. When they first brought it out it was only a two and a half year old medication. They were way too quick to bring it to market. It needs to be take off NOW! Before it harms anyone else. As I've seen people say we should contact an attorney. I think it's a good idea. I contacted the FDA 2 years ago. Well you see how well that worked."

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  • Brand...
  • Taken for 2 to 5 years
  • January 25, 2020

For High Cholesterol "Cardio Dr put me on Repatha and have been taking it now several years. I have had sore legs and arms etc but attributed it to ageing (70 now). The pain has gotten progressively worse to the point where I could only walk a few blocks. Now I can hardly walk across the house as all my muscles feel like rubber. I took my last shot two weeks ago and am not taking any more. Statins ruined me and I recovered somewhat when I quit them. This stuff is finishing the job. It did however lower my numbers but the pain and crippling just ain't worth it."

2 / 10
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  • BillZ
  • Taken for 1 to 6 months
  • August 21, 2020

For High Cholesterol "Started Repatha because I am hyper-sensitive to statins. Took 4 shots. After the 3rd, I started feeling the side effects. Slight rash on chest. My right nipple is very hard all the time (I'm a man)and painful. Over two months spread to left side with similar result. Wearing a bandaid on both of my nipples to reduce irritation. Face is red and very dry. Eyes are slightly bloodshot. Slight head ache all the time (not enough to stop me from my usual activity) Last shot my palms itched for a while, but went away. Blood work taken: prolactin levels abnormal, A1C elevated, blood sugar doubled. Doctor ordered brain scan for pituitary gland (prolactin). Negative. Doctor told me to stop taking Repatha. I hope these symptoms go away. Oh, and by the way it did lower my cholesterol."

3 / 10
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  • Twey
  • Taken for less than 1 month
  • May 29, 2021

For Cardiovascular Risk Reduction "After an event of cardiomyopathy, I took pill form of statins. Each one I tried gave me terrible leg pain. Cardiologist’s PA then prescribed Repatha. I took one dose of 140 mg on a Sunday, and by Tuesday I had to be taken to the hospital via ambulance due to being completely immobile with back pain. It is now Friday; I’ve had a dye contrast MRI and there is nothing found to be wrong with my back. I went from being perfectly mobile to being disabled, possibly permanently. I am now on three blood pressure medications where I was previously on one, and heavy narcotics to control pain. Even with all of this, the pain is still not entirely controlled, and I can’t move without the help of two nurses to use the bathroom or walk. After some heavy research, my daughter discovered that Repatha can permanently damage the musculature within the body. I BEG of anyone prescribed Repatha to never use it. It’s criminal that it was ever approved by the FDA. Please, Stay away from this medication!"

1 / 10
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  • JJano
  • Taken for 1 to 6 months
  • December 13, 2020

For High Cholesterol "I started using Repatha for 3 months due to statins side effects. I stopped using Repatha because I was experiencing severe shortness of breath, coughing, running nose and fatigue. Since stopping, my cough has almost gone away, I still get the occasional running nose and flu like symptoms. My breathing and fatigue is still a problem, my lung doctor tell me I lost 30% of my lung capacity and the cardiologist referred me for a pace maker after reviewing my electrocardiogram. It has only been 30 days since stopping this drug and it’s my understanding that it will take 60 to 90 days for this drug to completely get out of my system. I am extremely concerned about my current condition. I can’t do much, I struggle to breath and at times I am extremely fatigued. My quality of life is horrible, be very careful and consult your doctor if you start to suffer some of the side effects."

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  • Helen...
  • Taken for 1 to 2 years
  • February 3, 2024

For High Cholesterol "I am unable to take any statins due to terrible muscle cramping in my legs, feet, and back. My primary doctor referred me to a cardiologist as arteriosclerosis and heart disease run in my family. She recommended Repatha, which has worked remarkably. My LDL went from 277 to 78 within 3 months. All my liver function, kidney, and sugar numbers remain normal on my blood tests. I have no high blood pressure. I have experienced no side effects except one that supposedly isn't from the Repatha. I have been taking this medication for just over a year, and my weight has increased by over 12 pounds. I work hard on my diet and exercise, and I can't explain the weight gain. It's just too coincidental. My cardiologist denied that the Repatha is causing the weight gain and recommended a diet book. Despite the weight gain, I am pleased with my cholesterol results and will continue taking Repatha. But I am curious if anyone else has experienced weight gain from it. Additionally, the results from my latest carotid artery ultrasound have improved, which is evidence of the Repatha working."

9 / 10
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  • Marika
  • October 18, 2020

For High Cholesterol "The Repatha slowly is making me worse. My health is deteriorating for the last 2 years of using it. It’s awful. It has made my GI really bad from top to bottom Nausea , constipation, Etc. Light headed , muscle weakness , High blood pressure. Fast heart beat Extreme fatigue Loss of appetite, weight lost It’s not worst it ."

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  • Dee
  • Taken for 1 to 6 months
  • January 30, 2020

For High Cholesterol "I was on Repatha (140mg) every 2 weeks for high cholesterol. While I have never experienced flu like symptoms, I did notice my blood sugar increasing almost immediately. As a type 2 diabetic, I adhere to a strict low carb diet and exercise 5-6 days a week. My fasting blood sugar (before Repatha) ran between 99 and 117. Within 1 week after my first injection, my blood sugar jumped to the 130s and 140s. My A1C also increased. I had to increase my Metformin as well. Unfortunately that didn’t help so I opted not to continue to take Repatha. I have been off Repatha for 2 months and am still having problems with high blood sugar! I’m concerned about what damage Repatha might have caused! I am going to report this to the FDA and hope that they will open their ears and listen to all who have had significant dangerous and serious side effects from this “wonder drug”!"

3 / 10
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  • Midge
  • March 9, 2020

For High Cholesterol "I was put on repatha for high cholesterol. I am a 60-year-old female. I started first by gagging every morning. I took repatha for six months. I stopped taking it. And now for three months I still have a bad cough which is constant all day. I also have back pain that will not go away. I am hoping that these side effects will subside but they haven’t so far. I have take a nose spray pills cough medicine and still cough. I hope over time it stops my back pain keeps me awake at night. I recommend you don’t try this drug it’s not worth it. I still don’t know yet what I will be doing about my cholesterol. But it definitely won’t be taking the repass ever again. The symptoms seem to not go away. The last three months have been hell for me."

6 / 10
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  • John...
  • Taken for 1 to 6 months
  • April 11, 2023

For High Cholesterol "I had a really bad experience with the 140ml injection. After a month I was having panic attacks regularly and feeling of brain fog. It was very scary. My primary care physician asked me to stop using it and 2 to 3 weeks later the panic attacks disappeared and the brain fog improved and now I'm back to normal. Tried reaching out to the AMGEN the company that makes this product because I had 1 month supply of the repatha to see if I can get reimbursed, but instead of helping me they just asked a bunch of research study question that they need and offered no help in any way. Horrible company and it's a very dangerous product. Think twice before you take this."

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  • Bobby
  • January 4, 2020

For High Cholesterol "I have been taking repatha for about 2yrs. At first I had no side effects and my cholesterol levels went down to 26. Now I have all kinds of side affects, severe back and side pain..Short of breath, severe muscle cramps blurred vision, dizzy, weight lose, loss of appetite..etc. I'm considering not taking it anymore"

10 / 10
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  • Fluffy
  • March 30, 2021

For High Cholesterol "Took Repatha on Feb. 15, 2021 leg started swelling. Called dr as leg went pins & needles. Next day cough, sneezing, nose runny. Next day all of the above with swollen lip, sores in mouth, cheeks breaking out face sores & forehead. Itchy face & bladder feels stiff, can not pee it is strong smelling. Ankle swollen, vagina swollen, had asthma attack went to ER. Stuffy nose, headache watery eyes. BP running high 152/92. Woke up at 3am not feeling good bp189/91, ears hurt, face hurts. Post nasal drip, ears ache, coughing, face red & sores. March 5th going down chest with itchy red bumps. Its continuing in cycles 11-17 days up to 93 days. It is March 29 & I have sores on face, ears ache, throat hurts, sores came back in mouth, & now leg pain. I'm exhausted. This medicine is poison to me. My cholesterol numbers will just have to be high. I cant take statins. NEVER DOING THIS AGAIN. I hope I survive it! Called the fda."

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  • Zig-Zag
  • February 26, 2020

For High Cholesterol "I have taken 5 injections and my cholesterol was cut in half! But the side effects are terrible! Legs are weak and feel disoriented and feel really tired! Going to quit taking this not worth feeling bad!"

9 / 10
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  • Buddy
  • Taken for 6 months to 1 year
  • February 28, 2020

For High Cholesterol "I started taking Repatha because other statins caused me to have joint pain and my bad cholesterol numbers were still higher than my heart doctor wanted. Within a month of starting I was having cold symptoms and started having a nagging cough. I then started having lung congestion and wheezing especially at night. Fast forwarding several months I had to go to the emergency clinic 5-6 times due to an inability to breathe. I have been on Prednisone 5 times have been given breathing treatments, albuterol inhalers and singulair. I stopped taking the injections about a month ago and am still having symptoms especially as soon as I lay down. I have also been using nose sprays twice a day. I have never smoked and never had any breathing problems before. Really praying I get over these issues soon."

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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.