Repatha for High Cholesterol User Reviews

• Pon...
• Taken for 1 to 6 months
• August 25, 2020

"I have previously been unable to take any cholesterol medicine because it bothered my muscles. I have tried five different kinds of cholesterol medication. My doctor was finally able to get my insurance to cover Repatha. I have taken three doses, so for a month and a half. My muscles started to feel tight in both legs and then a weakness on one side. I had a CK blood test a week ago and instead of 14, it was 936! Since nothing has changed besides Repatha, my doctor told me to stop taking it. This is truly a frightening scenario since Repatha is being sold as a medication that does not affect your muscles!"

• Anonymous
• Taken for 6 months to 1 year
• February 25, 2020

"So, 1 out of 1000 users of Repatha have no issues. For others who are suffering, start calling attorneys, call and report to FDA. Best of all, hopefully someone calls 60 minutes to do a story. Enough is enough. This is heartbreaking what Repatha is causing all these side effects, and they know it. It’s all about money."

• Rob...
• Taken for less than 1 month
• May 7, 2021

"I have been on numerous cholesterol-lowering statins for over twenty years. First Lipitor, then Crestor, and then Repatha. Lipitor caused me to have very painful problems and cramping in my ankles and Achilles tendons so I switched to Crestor. I was on Crestor for quite a few years without many problems that I could see, but I did manage to tear both my biceps and had to repair both surgically. My neck pain was out of control while on Crestor and I consulted a neurosurgeon who fused me between C6-7 in my neck. After that surgery, I have been unable to take anything for my cholesterol. In July of 2020, I was diagnosed with AFib and sent to a cardiologist who did blood tests and wanted me to try Repatha. I tried it, and within a few days, the neck pain was considerably unbearable. Also, I was short of breath quite substantially. I don't know about the statin drugs or Repatha. They both don't agree with me at all. Guess I'll have to take my chances."

• Gfi...
• March 3, 2020

"12/12/19 first Repatha injection taken at 1:30 p.m. (4 years post renal transplant). Doc assured me it would be no problem. Sitting watching TV at 9 p.m., broke out in sweat, had the feeling of cold water running through my sinus cavity on one side only. Rapid heartbeat, blood pressure spiked, cramps in calves and back of thighs for several nights. Major flu-like symptoms off and on since injection. Visits to neurologist, cardiologist, and general practitioner all say it can last for quite a while, half-life ranges from 11 to 17 days, so for most of it to clear my body could be up to 93 days. Now having esophagus and stomach problems. Never had this before. I believe that not many trial tests were done on taking Repatha with anti-rejection meds. But from my experience, they don’t blend well with Repatha. Still feeling like rubbish, have a good day or two and then it’s back, just don’t have a consistent feeling of well-being. 81 days out. Has anyone fully recovered and if so, how long did it take? I’m a 58-year-old male."

• Woo...
• Taken for 2 to 5 years
• February 29, 2020

"I had a heart attack in late 2004 and double bypass in early 2005 at 42. I can't tolerate statin drugs, so my doctor said there was a great new drug out there called Repatha. It was a miracle drug, so I started taking it. After about two years, I started having lots of muscle pain, cramps, and severe headaches. Five months ago I had a stroke. At the time, I thought I was having a migraine. My doctor took several MRIs, X-rays, and CAT scans but could not determine what caused the stroke. I suspect that Repatha was the cause. If you are on Repatha, please stop taking it right now. It is not worth it. This drug should be taken off the market fast before someone dies. I could have, but was very lucky."

• SRS...
• Taken for 1 to 2 years
• June 10, 2024

"Repatha did well in reducing my LDL levels to anywhere from 6-15. That is the good. The bad. GI issues, I was making 5-7 trips a day to the restroom. Muscular pain in the legs, arms, and back. Joint pain. Numbness in both hands. Ear congestion. Stuffy nose and coughing. Chest congestion. It’s terrible that the pharmaceutical companies are allowed to produce and distribute medications that have the ability to put people in harm's way."

• Bra...
• Taken for 2 to 5 years
• January 25, 2020

"Cardio Dr put me on Repatha and have been taking it now for several years. I have had sore legs and arms, etc., but attributed it to aging (70 now). The pain has gotten progressively worse to the point where I could only walk a few blocks. Now I can hardly walk across the house as all my muscles feel like rubber. I took my last shot two weeks ago and am not taking any more. Statins ruined me, and I recovered somewhat when I quit them. This stuff is finishing the job. It did, however, lower my numbers, but the pain and crippling just ain't worth it."

• Kar...
• January 28, 2020

"I've been off of Repatha for almost 2 years. I still have extreme muscle weakness in my legs. I fear this may be permanent. This is the worst drug on the market. When they first brought it out, it was only a two and a half-year-old medication. They were way too quick to bring it to market. It needs to be taken off NOW! Before it harms anyone else. As I've seen, people say we should contact an attorney. I think it's a good idea. I contacted the FDA 2 years ago. Well, you see how well that worked."

• Bil...
• Taken for 1 to 6 months
• August 21, 2020

"Started Repatha because I am hypersensitive to statins. Took 4 shots. After the 3rd, I started feeling the side effects. Slight rash on chest. My right nipple is very hard all the time (I'm a man) and painful. Over two months spread to left side with similar result. Wearing a bandaid on both of my nipples to reduce irritation. Face is red and very dry. Eyes are slightly bloodshot. Slight headache all the time (not enough to stop me from my usual activity). Last shot my palms itched for a while, but went away. Blood work taken: prolactin levels abnormal, A1C elevated, blood sugar doubled. Doctor ordered brain scan for pituitary gland (prolactin). Negative. Doctor told me to stop taking Repatha. I hope these symptoms go away. Oh, and by the way, it did lower my cholesterol."

• JJa...
• Taken for 1 to 6 months
• December 13, 2020

"I started using Repatha for 3 months due to statins' side effects. I stopped using Repatha because I was experiencing severe shortness of breath, coughing, runny nose, and fatigue. Since stopping, my cough has almost gone away. I still get the occasional runny nose and flu-like symptoms. My breathing and fatigue are still problems. My lung doctor tells me I lost 30% of my lung capacity, and the cardiologist referred me for a pacemaker after reviewing my electrocardiogram. It has only been 30 days since stopping this drug, and it’s my understanding that it will take 60 to 90 days for this drug to completely get out of my system. I am extremely concerned about my current condition. I can’t do much, I struggle to breathe, and at times I am extremely fatigued. My quality of life is horrible. Be very careful and consult your doctor if you start to suffer some of the side effects."

• Joh...
• Taken for 1 to 6 months
• April 11, 2023

"I had a really bad experience with the 140ml injection. After a month, I was having panic attacks regularly and feeling of brain fog. It was very scary. My primary care physician asked me to stop using it, and 2 to 3 weeks later, the panic attacks disappeared, and the brain fog improved, and now I'm back to normal. Tried reaching out to Amgen, the company that makes this product, because I had a 1-month supply of Repatha to see if I can get reimbursed, but instead of helping me, they just asked a bunch of research study questions that they needed and offered no help in any way. Horrible company, and it's a very dangerous product. Think twice before you take this."

• Mar...
• October 18, 2020

"The Repatha slowly is making me worse. My health is deteriorating for the last 2 years of using it. It’s awful. It has made my GI really bad from top to bottom. Nausea, constipation, etc. Light-headed, muscle weakness, high blood pressure. Fast heartbeat, extreme fatigue, loss of appetite, weight loss. It’s not worth it."

• Mid...
• March 9, 2020

"I was put on Repatha for high cholesterol. I am a 60-year-old female. I started by gagging every morning. I took Repatha for six months. I stopped taking it, and now for three months, I still have a bad cough which is constant all day. I also have back pain that will not go away. I am hoping that these side effects will subside, but they haven’t so far. I have taken a nose spray, pills, cough medicine, and still cough. I hope over time it stops, my back pain keeps me awake at night. I recommend you don’t try this drug, it’s not worth it. I still don’t know yet what I will be doing about my cholesterol, but it definitely won’t be taking Repatha ever again. The symptoms seem to not go away. The last three months have been hell for me."

• Dee...
• Taken for 1 to 6 months
• January 30, 2020

"I was on Repatha (140mg) every 2 weeks for high cholesterol. While I have never experienced flu-like symptoms, I did notice my blood sugar increasing almost immediately. As a type 2 diabetic, I adhere to a strict low-carb diet and exercise 5-6 days a week. My fasting blood sugar (before Repatha) ran between 99 and 117. Within 1 week after my first injection, my blood sugar jumped to the 130s and 140s. My A1C also increased. I had to increase my Metformin as well. Unfortunately, that didn't help so I opted not to continue to take Repatha. I have been off Repatha for 2 months and am still having problems with high blood sugar! I'm concerned about what damage Repatha might have caused! I am going to report this to the FDA and hope that they will open their ears and listen to all who have had significant dangerous and serious side effects from this 'wonder drug'!"

• Bob...
• January 4, 2020

"I have been taking Repatha for about 2 years. At first, I had no side effects and my cholesterol levels went down to 26. Now I have all kinds of side effects: severe back and side pain, shortness of breath, severe muscle cramps, blurred vision, dizziness, weight loss, loss of appetite, etc. I'm considering not taking it anymore."

• Flu...
• March 30, 2021

"Took Repatha on Feb. 15, 2021. Leg started swelling. Called dr as leg went pins & needles. Next day cough, sneezing, nose runny. Next day all of the above with swollen lip, sores in mouth, cheeks breaking out, face sores, & forehead. Itchy face & bladder feels stiff, can not pee, it is strong smelling. Ankle swollen, vagina swollen, had asthma attack & went to ER. Stuffy nose, headache, watery eyes. BP running high 152/92. Woke up at 3 am not feeling good, bp 189/91, ears hurt, face hurts. Post nasal drip, ears ache, coughing, face red, & sores. March 5th going down chest with itchy red bumps. It's continuing in cycles 11-17 days up to 93 days. It is March 29 & I have sores on face, ears ache, throat hurts, sores came back in mouth, & now leg pain. I'm exhausted. This medicine is poison to me. My cholesterol numbers will just have to be high. I can't take statins. NEVER DOING THIS AGAIN. I hope I survive it! Called the FDA."

• Zig...
• February 26, 2020

"I have taken 5 injections, and my cholesterol was cut in half! But the side effects are terrible! Legs are weak, feeling disoriented, and very tired! I'm going to quit taking this, not worth feeling bad!"

• Bud...
• Taken for 6 months to 1 year
• February 28, 2020

"I started taking Repatha because other statins caused me to have joint pain, and my bad cholesterol numbers were still higher than my heart doctor wanted. Within a month of starting, I was having cold symptoms and started having a nagging cough. I then started having lung congestion and wheezing, especially at night. Fast forwarding several months, I had to go to the emergency clinic 5-6 times due to an inability to breathe. I have been on Prednisone 5 times, have been given breathing treatments, albuterol inhalers, and singulair. I stopped taking the injections about a month ago and am still having symptoms, especially as soon as I lay down. I have also been using nose sprays twice a day. I have never smoked and never had any breathing problems before. Really praying I get over these issues soon."

• Aaa...
• December 9, 2019

"My doctor also told me there were no side effects. So, initially, I was thrilled to get a chance to try it. It took 10 days for side effects to appear, waking me at 3 AM with severe pain in my ankles, calves, hips, and neck with spasms in the ankle, but those symptoms subsided after a day. After the second injection, it took only 3 days for severe tendon pain to hit my left leg, leaving me barely able to walk. I was shuffling like a 90-year-old. I went to an ortho who ordered an MRI. He said the pain I had was medicine-induced. I asked my cardiologist about the symptoms, along with severe insomnia, but he denied it was from Repatha. My PCP encouraged me to stick with it due to the very low cholesterol numbers, so I took a third injection and quit after that. But 3 months later, there is little relief. The reduced quality of life has not been worth this! What bothers me is the automatic denial by the doctors who are so quick to say NO ONE else has complained. Really?"

• Lin...
• Taken for 1 to 6 months
• February 21, 2025

"I have been taking Repatha for about six months. It has worked very well to bring my LDL down. My first injection caused no problem, but after the second injection, within 24 hours, I had nerve pain all over my body. This lasted for a day and a night. I decided to stick it out and hope that these symptoms would eventually go away. In the fourth month of taking Repatha, I suddenly woke up one morning with very stiff fingers in both hands along with swelling. I didn't think much about it at first, but the pain and stiffness with the swelling has gotten worse. My physician says the only way to know if Repatha is causing this is to discontinue and see what happens. I am also having muscle pain in the back of my legs that I have never experienced. I am no longer taking Repatha, for I feel strongly that it is definitely causing the hand problem. It is very painful and there was a sudden onset. I don't recommend taking Repatha."

• Nth...
• Taken for less than 1 month
• May 1, 2024

"Was having trouble with statins after my cardiologist upped my medication. Mostly tingling in my lower legs. Got approved for Repatha. Took shot and first two days everything was fine until day three. Leg tingling came back (actually a bit worse than statins). Will not take another shot of it. Currently on Day 17 after taking shot and won’t be taking another one either. Repatha stays longer in the system (2-3 months). Hoping the side effects start going away. Not fun! Super frustrated. I’m putting this out there because neuropathy isn’t listed as a common side effect but it sure is for me! Drug may work for others though. I was so optimistic too."

• Sic...
• January 10, 2020

"The best advice I have for all you poor patients is to call an attorney. This drug should be removed from the market, it’s causing too many horrible adverse reactions. You poor patients should not be experiencing this. The problem I have with all these reports on here is that it’s being kept quiet from Amgen. Someone needs to start investigating this drug starting with all the FDA & Amgen’s reports they have, or maybe someone should call 60 Minutes and let them investigate this, then something might get done."

• alw...
• Taken for 6 months to 1 year
• November 20, 2022

"I started on Repatha in January of this year. I read the reviews here but dismissed them as only a small group of bad experiences. After all, a couple of cardiologists had told me Repatha was 'well tolerated' and had no side effects. Everything was going fine until I was about 8 months in, and then I began to feel off, initially foggy, blurry, dizzy, and difficulty thinking. I initially doubted myself because, after all, this drug has been pitched as not having the side effects of the statins. I took one more injection of Repatha after these initial symptoms and was then almost incapacitated. Complete spaced-out feeling, blurred vision, dizzy to the point of almost falling a couple of times, unable to think clearly. Literally, the worst side effects I've ever felt in my life. I was terrified I had seriously damaged my brain. Thankfully, after stopping the Repatha, my symptoms began to clear up around 18 days after the last injection. The reviews here are real, and this is a very troubling drug."

• Ang...
• Taken for 1 to 6 months
• December 17, 2024

"I have genetically high cholesterol that can’t be helped with diet or exercise. I also have an inability to take statins because they make all my joints and muscles hurt. I started taking Repatha injections. No side effects that were noticeable the first 6 injections. Now, my body feels horribly achy all the time. My lower back, neck, hips, legs, and arms. At first, I attributed it to all the boxes I was packing for my move. But now, it feels like I’m losing strength and muscle mass, and I hurt all over. Now that I’ve read all the reviews, I think I will stop using Repatha and see if my pain improves because I can’t handle getting any worse! I’m supposed to test my cholesterol at the six-month mark, but I’m stopping injections at the four-month mark."

• Hel...
• Taken for 1 to 2 years
• February 3, 2024

"I am unable to take any statins due to terrible muscle cramping in my legs, feet, and back. My primary doctor referred me to a cardiologist as arteriosclerosis and heart disease run in my family. She recommended Repatha, which has worked remarkably. My LDL went from 277 to 78 within 3 months. All my liver function, kidney, and sugar numbers remain normal on my blood tests. I have no high blood pressure. I have experienced no side effects except one that supposedly isn't from the Repatha. I have been taking this medication for just over a year, and my weight has increased by over 12 pounds. I work hard on my diet and exercise, and I can't explain the weight gain. It's just too coincidental. My cardiologist denied that the Repatha is causing the weight gain and recommended a diet book. Despite the weight gain, I am pleased with my cholesterol results and will continue taking Repatha. But I am curious if anyone else has experienced weight gain from it. Additionally, the results from my latest carotid artery ultrasound have improved, which is evidence of the Repatha working."