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User Reviews for Praluent

The following information is NOT intended to endorse drugs or recommend therapy. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners in patient care.

Condition Avg. Ratings Reviews Compare
High Cholesterol, Fa...ial Heterozygous
7.8
   
20 reviews 18 medications
High Cholesterol
6.2
   
40 reviews 53 medications
Cardiovascular Risk Reduction
5.8
   
6 reviews 14 medications
Summary of Praluent reviews 6.5 66 reviews

Reviews for Praluent

For High Cholesterol "I've had my 2nd injection @ 150mg dose last week. Don't know my numbers yet but the side effects are identical to when I started Crestor drug. My whole body hurts, hard to walk very far without severe muscle pain. Can't sleep because of muscle pain. I feel like death warmed over. Last dose for me."

   
5.0

Mike June 12, 2019

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For High Cholesterol, Familial Heterozygous "I am 42, Cabgx3. I had a Triple bypass graft in December of 2018. My total cholesterol was running between 450 and as high as 640 before. I’m 6’1 and 215 lbs. I am Active and eat healthy. 34” waist. No red meat or pork since surgery. I have never been able to tolerate Statins. They absolutely kick my butt. Since surgery I have been taking 150mg injections of praluent every 2 weeks with ZERO side effects. I’m on at least my 10 or 12 th injection and my cardiologist has yet to recheck my cholesterol. Surgeon said with my cholesterol history if this drug doesn’t work for me then I’d see him again in about 4 years. Lol. Hopefully that’s not the case. I’ll update when I get my levels checked next visit but for now I can report NO Side effects."

   
8.0

Rob (taken for 1 to 6 months) May 14, 2019

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For High Cholesterol, Familial Heterozygous "61 y.o. female with FH (familial high cholesterol ): I had pre-existing neuralgia which was somewhat manageable, I tried statins and they brought my pain levels to 10+ so no statins for me. Praluent was okay regarding neuralgia for the first few months when I was yanking out the needle at the halfway point (due to a bad reaction to Repatha in 2018...another story for another day). 8 weeks ago when I started leaving the needle in until it retracted, i.e., giving myself the full 75 mg, that's when my neuralgia started to break through intensely. Very disappointing. I hope that, going back to the half dose, even though it's very hard to estimate when to pull out the needle -- the needle is so fast, I hope to reverse the increased neuralgia. I need a full dose but it looks like I can't tolerate it. Dang! When the nerve pain increases, my good mood disappears."

   
5.0

Stairs (taken for 6 months to 1 year) April 29, 2019

7 users found this comment helpful.
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For High Cholesterol, Familial Heterozygous "Have had no problems in 18 months. First time in adult life with normal cholesterol Had stent/ minor heart attack almost two years ago. Now have some neuropathy in hands and feet. Has anyone else had this problem?"

Lee (taken for 1 to 2 years) April 9, 2019

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For High Cholesterol "I was on Repatha for years with no problems. Insurance provider stopped coverage, but offered coverage for Praluent. Out of pocket cost to me for three month supply of .75mg every two weeks is $720.00. Taken it twice. Sore in mouth, lower back pain, and weak legs to go with overall feeling of tiredness/weakness. Biggest concern is that my blood pressure and pulse have gone off the scale, which is something I did not previously experience and seem incapable of bringing it down regardless what I do. Always had excellent numbers without medication. Had Afib three times in a two-day period. To put it mildly, I have severe reservations the plus side of this medication is worth the side effects. Life without quality seems to be lacking in the basic tenant."

   
2.0

kenjam (taken for 1 to 6 months) March 24, 2019

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For High Cholesterol, Familial Heterozygous "I cannot tolerate statins so I've been taking Praluent for a few years and my bad cholesterol is way down and my good cholesterol is up to an acceptable level. But know I am thinking the praluent side effect is body pain and aches as for about the past six months I have been experiencing somewhat severe whole body pain. I feel better if I take Norco or Tramadol which I use for back pain, but on advice of my cardiologist I skipped the last Praluent dose to see if I feel any better. Praluent has a half-life of 17-20 days so I figure I'll need to wait at least 40 days to see if I feel better. I sure hope the Praluent is not the cause because it's keeping me alive. I'm 66 and my father died at age 57 from a heart attack. For me the only solution might be to increase my pain meds. I already have two completely clogged heart arteries so I need to do something to keep my liver from making too much cholesterol. Changing my diet did nothing."

   
7.0

JamesBon92007 (taken for 2 to 5 years) March 15, 2019

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For High Cholesterol, Familial Homozygous "Some nasal/fatigue issues at first, but those went away within months. Praluent had lowered my LDL around 55% and no major side effects. I love this drug."

   
10

cmccready (taken for 2 to 5 years) March 5, 2019

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For High Cholesterol "Awesome stuff for me. No side effects. Cut the pravastatin in half 40mg pravastatin 1x daily plus 75mg alirocumab every other week HDL down from 399 to 85mg dl. Still taking the other stuff. Livolo works fairly well but not like this. Can't tolerate ACE inhibitors and some med put a bruise across my back within three days. instant kidney damage. Now blue cross wants to deny me the only med combo I could tolerate. Actually prime theraputics is doing that. Forwarding their denial to cardio and via my atty to oag and state insurance board. After one 4x cabg 3 stents 2 mi. Bilateral endarectomy and original LDL around 400. I think my widow will be a millionaire as for ME.. we can prove this is the best and most correct treatment plan and it did work for about 5 years until they decided they should play doctor..."

   
10

Jr (taken for 5 to 10 years) January 24, 2019

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For High Cholesterol "Excellent medicine. It reduced my LDL cholesterol to 25 mg and also reduced the triglycerides to 75 mg. Raised HDL cholesterol to 51 mg. I did not feel any side effects."

   
10

Luis (taken for 1 to 6 months) January 17, 2019

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For High Cholesterol, Familial Heterozygous "Just about to take my third injection of Praluent but from day one I have had diarrhoea and upset stomach...anyone else had these symptoms?"

Suzy (taken for less than 1 month) December 31, 2018

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For High Cholesterol "Dramatic reduction in total cholesterol after about 1.5 years. 62 year old female. Went from 250 down to now 107. Have gradually been getting more and more fatigued, weaker and now to the point I can't do my walks. Going to call cardiologist after the holidays. This is how I felt on statins after just a few days. I'm disappointed. Very easy to use med."

   
8.0

Frida (taken for 1 to 2 years) December 24, 2018

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For High Cholesterol "I am getting no side effects from Praluent 75mg after 7 injections , 2 months time. I had to stop taking Rosuvastatin 40 mg due to stabbing back muscle pain. My doc switched me to Lipitor statin 10 mg every other day. So far no side effects. My latest LDL test was 30. A year ago my LDL was 210."

   
10

mk3509 (taken for 1 to 2 years) December 2, 2018

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For High Cholesterol, Familial Heterozygous "I've been on praluent for 5 years now. First in a clinical trial, then phase 2 trial and now as prescribed by my lipid specialist. I have had NO side effects whatsoever. I am now 50 years old, and take crestor 40mg and praluent 150mg. I've been on statins for 20 years which reduced my total cholesterol & LDL moderately but still elevated (240 total)( 190 lDL) my current level 170 total and 71 LDL. I am not overweight and exercise a couple times per week. I have had an abnormal calcium score and noted plaque in my right carotid. I feel this drug is saving my life."

   
10

Jimmy (taken for 2 to 5 years) December 1, 2018

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For Cardiovascular Risk Reduction "Have genetic high cholesterol plus cardiovascular risk. Taking statins caused myopathy resulting terrible muscle aches and pains. I have been on Praulent 75mg. Twice monthly approximately 2 years. I am a very active soon to be 70 years old however after sitting a least 10 minutes It is unbearable to raise my body and start walking as my body is very stiff. Hard to get my feet to move...I ache from my lower back down to feet...my insides feel very sore and I have developed terrible nose sores! I am afraid if I take it much longer I will be unable to walk. I was hoping that the Praulent was safe for me and in the beginning of using Praulent I was pleased with the thought of it lowering of my cholesterol and no side effects. Not sure what to do now!"

   
6.0

Lake lady (taken for 1 to 2 years) November 27, 2018

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For High Cholesterol, Familial Homozygous "The medication is being taken in addition to statins. I have never had issues with my Crestor or Zocor, but my numbers were not low enough. The medication with the statin has brought my total cholesterol to 142 and L DL down considerably. I have noticed worsening vision, joint pain in my hips and knees and a strange hoarse voice. I cannot say that the Prauluent is the cause, but I am having these investigated. The onset of symptoms seems to align with the new medication, but it also aligns with being 50 ish and maybe everyone feels like rubbish at this age."

   
6.0

SuzeeQ (taken for 2 to 5 years) October 23, 2018

9 users found this comment helpful.
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For High Cholesterol, Familial Heterozygous "Now my numbers are perfect. This is a silver bullet for me after one year on drug, Cholesterol is perfect, my blood pressure is normal. It is a life saver."

   
10

steve (taken for 1 to 2 years) October 18, 2018

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For High Cholesterol "I've been taking Praluent 75 for 2 months now and report no side effects. I take ibupropen before the injection so I don't feel the small bee sting feeling in my leg. I am 70 yrs old and hope to take the injection forever to prevent another heart attack and a $55,000 bill for 2 days in the hospital. 10-10-2018. Express Scripts just sent me a letter approving my prescription."

mk3509 (taken for 1 to 6 months) October 14, 2018

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For High Cholesterol "I'm a 64 yr old male. I have had 2 MI (heart attacks)... first at age 46, the second at age 61 which resulted in me having a CABGX3 (Coronary artery bypass graft surgery - three grafts. I have been taking 75mg Praluent for about 5 months at twice monthly injections. Over the last few injections I have noticed a slight increase in muscle pain in legs and lower back. I also feel pain and discomfort in abdominal area. Anyone notice abdominal discomfort as well?"

   
5.0

Bazzle October 12, 2018

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For High Cholesterol "I have had two shots getting ready for my third not sure if I want to take it because I've had chills, headache nausea a lot also aching. I'm going to get my blood test tomorrow to see if it's lowered it enough for me to keep taking this cuz the side effects for me are horrible. Also my blood pressure goes from being high to drastically low."

   
5.0

Me October 11, 2018

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For High Cholesterol "I am a heart patient. I’ve had one heart attack and another one milder one a year ago. I have taken two injections with not too many noticeable side effects. Maybe some isolated aches and pains and maybe a little tightness in my chest. After the 1st week of the second injection. I checked my BP 169/95, checked again the 2nd day. 159/99. Way too high for a heart patient! Then it goes down too low. 95/69 etc. I have done reported this to the FDA. I don’t need this. I called my doc and was told by a nurse to increase my BP meds but I told them NO!. Not till I talk to my regular heart doc and primary care doc in person. I’m done with this med for now. If I am going to die I would rather die from not taking this med. If I die from taking this med, what’s the point? I don’t think a long range study on side effects from this med has been done. It hasn’t been out long enough."

   
2.0

arcey October 8, 2018

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For High Cholesterol, Familial Heterozygous "My total cholesterol dropped from 206 to 109 after 3 shots. No side affects however dr still has me taking Crestor 40mg and zetia 10 mg. Anyone else on both drugs."

   
10

Ski (taken for 1 to 6 months) October 4, 2018

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For Cardiovascular Risk Reduction "I'm a 53 year old male I've had quadruple bypass , stints and been diabetic for 43 years Started taking three months ago haven't had blood work yet for results. But the side effects been having a sore nose also sores inside my nose and bumps on my body with very large swelling . I never had this before taking Pradulent "

   
4.0

mmmhj (taken for 1 to 6 months) October 3, 2018

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For High Cholesterol, Familial Heterozygous "I had been taking statins for years and worked my way through all the brands with multiple side effects. I have injected myself with three doses of Praluent over a six week period and my cholesterol has come down 60% and let have had no side effects."

   
9.0

tammy (taken for 1 to 6 months) September 26, 2018

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For High Cholesterol "I have been on Praluent for 3 months and my cholesterol has gone up from 8 to 12.4!.....LDL has gone into double figures too. Have been changed onto another injection. Bitterly disappointed."

   
1.0

Dissapointed (taken for 1 to 6 months) September 21, 2018

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For High Cholesterol, Familial Heterozygous "Praluent ruined my life! I was diagnosed with familial hypercholesterolemia and was prescribed Praluent by the cardiologist. If I knew then what I know now I would have never have taken this poison. From the moment I took my first & last Praluent injection my heart started beating rapidly, my chest tightened up, short of breath, severe stomach pain, anxiety and vomiting! I was admitted to the hospital and doctors had no idea what Praluent is and I had to explain while I was in critical condition. Their advise was don't take anymore injection and wait until the Praluent gets out of my system which can take up to 3 months! Three months have passed and I am now in constant pain! I'm on strong pain killers, steroids and anti nausea medication. I also developed hypertension and I can't seem to bring it down even with meds! I don't think I will ever recover from this. If anyone had similar experience and had treatment for the horrible life changing side effects please share it with us."

   
1.0

CholAlex (taken for less than 1 month) September 15, 2018

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