Praluent for High Cholesterol, Familial Homozygous User Reviews

• Lil...
• March 18, 2023

"Due to my high cholesterol level of 365, I was unable to take statins. I am a 67-year-old female. I had been taking a 75 mg dose for six months, but in the last few months, I noticed several stomach issues, including diarrhea. After the last two shots, I experienced numbness in my hands, followed by pain in my knees and legs. My hands also retained water to the extent that I had to remove my rings, something that had never been an issue before. After taking the last two shots, I woke up with severe chest pain, thinking it was indigestion, and felt like someone was sitting on my chest. Suddenly, my body felt like it was falling apart, so I went to my doctor to inform him that I would no longer take the medication. When I went in, my blood pressure was so high that I had to go to the hospital. My blood pressure and pulse rate were alarmingly high, which scared me immensely. I will never take this drug again because it has also triggered panic attacks. I pray that all of this is not permanent damage. This drug is poison."

• Frm...
• July 17, 2016

"After one injection, I experienced swelling of hands and feet. My blood pressure elevated by more than 50 points. Praluent researchers said I had an autoimmune reaction and that it all would pass as the Praluent left my system. After 8 months, I still have high blood pressure. I am currently being checked for vasculitis as the result of my autoimmune reaction."

• Suz...
• Taken for 2 to 5 years
• October 23, 2018

"The medication is being taken in addition to statins. I have never had issues with my Crestor or Zocor, but my numbers were not low enough. The medication with the statin has brought my total cholesterol to 142 and LDL down considerably. I have noticed worsening vision, joint pain in my hips and knees, and a strange hoarse voice. I cannot say that the Praluent is the cause, but I am having these investigated. The onset of symptoms seems to align with the new medication, but it also aligns with being 50-ish and maybe everyone feels like rubbish at this age."

• CCB...
• Taken for 1 to 6 months
• May 22, 2024

"Reduced cholesterol well. Injection pen painless and easy to use. Side effects of activity-limiting low back pain, muscle aching around hips and sides, occasional feelings of head pressure and mental fogginess, and often feeling very tired or drained. However, it works a LOT better and causes much less pain than statins!"

• Jud...
• Taken for 1 to 6 months
• November 29, 2022

"I'm 82 y.o. female. High cholesterol is in my family and no one has died of a heart attack. I tried statins and Ezetimibe with troubling side effects - pain and fatigue in legs and a high muscle enzyme number. Then the cardiologist put me on Praluent and after several months I began having a large welt at the injection site with every injection. Then I started getting a rash with blisters on my legs that itched. I also began having pain and fatigue in my legs again. I had my veins checked, my hips checked, and an MRI of my back (possible stenosis the orthopedist thought). Everything checked out fine! Had a biopsy done on the rash and was told it was from some allergy. I stopped taking the Praluent and a month later the pain in my legs is 99% gone and the rash has subsided. The Praluent definitely lowered my cholesterol but I don't tolerate it well."

• Anonymous
• Taken for 2 to 5 years
• January 19, 2023

"I have had success with this medication. My cholesterol levels were in the 300s initially but I had been getting treatment for many years (since a child) with just Crestor which brought the cholesterol levels down to the high 100-low 200s. My new lipidologist decided to add Praluent in combination with Crestor. I started on the lower dose and increased to a higher dose and have been taking the higher dose for the last 4 years. My levels are now under 100 and have been consistently great since then. I inject biweekly and find it easy to use. I have had no side effects at all."

• cmc...
• Taken for 2 to 5 years
• March 5, 2019

"Some nasal/fatigue issues at first, but those went away within months. Praluent had lowered my LDL around 55%, and no major side effects. I love this drug."