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Medications for High Cholesterol, Familial Heterozygous

Other names: Familial Hypercholesterolemia, Heterozygous; Heterozygous Familial Hypercholesterolemia; Heterozygous FH; Hypercholesterolemia, Familial Heterozygous

About High Cholesterol, Familial Heterozygous:  High cholesterol is the presence of high levels of cholesterol in the blood. Familial means that is passed down through families and is a genetic disorder. The altered gene that causes familial high cholesterol is located on chromosome number 19. It contains the information for a protein called LDL receptor that is responsible to clear up LDL from the blood stream. One in 500 individuals carries one altered gene causing familial hypercholesterolemia. These individuals are called heterozygotes.

Drugs Used to Treat High Cholesterol, Familial Heterozygous

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Popularity
Lipitor X N 2 reviews
8.0

Generic name: atorvastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

atorvastatin X N 4 reviews
6.0

Generic name: atorvastatin systemic

Brand name:  Lipitor

Drug class: statins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Crestor X N 6 reviews
8.0

Generic name: rosuvastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

pravastatin X N 1 review
6.0

Generic name: pravastatin systemic

Brand name:  Pravachol

Drug class: statins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

simvastatin X N 3 reviews
6.0

Generic name: simvastatin systemic

Brand names:  Zocor, FloLipid

Drug class: statins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Zetia C N 7 reviews
8.0

Generic name: ezetimibe systemic

Drug class: cholesterol absorption inhibitors

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Pravachol X N Add review
8.0

Generic name: pravastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Zocor X N Add review
5.0

Generic name: simvastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

lovastatin X N 3 reviews
6.0

Generic name: lovastatin systemic

Brand names:  Altoprev, Altocor

Drug class: statins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

rosuvastatin X N 8 reviews
8.0

Generic name: rosuvastatin systemic

Brand name:  Crestor

Drug class: statins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Vytorin X N 1 review
10

Generic name: ezetimibe / simvastatin systemic

Drug class: antihyperlipidemic combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

ezetimibe C N 9 reviews
8.0

Generic name: ezetimibe systemic

Brand name:  Zetia

Drug class: cholesterol absorption inhibitors

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

ezetimibe / simvastatin X N 1 review
10

Generic name: ezetimibe / simvastatin systemic

Brand name:  Vytorin

Drug class: antihyperlipidemic combinations

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, Prescribing Information

Repatha N 25 reviews
6.0

Generic name: evolocumab systemic

Drug class: PCSK9 inhibitors

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Altoprev X N 1 review
9.0

Generic name: lovastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

evolocumab N 29 reviews
6.0

Generic name: evolocumab systemic

Brand names:  Repatha, Repatha Pushtronex, Repatha SureClick

Drug class: PCSK9 inhibitors

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph

Praluent N 15 reviews
8.0

Generic name: alirocumab systemic

Drug class: PCSK9 inhibitors

For consumers: dosage, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Altocor X N Add review Rate

Generic name: lovastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

alirocumab N 15 reviews
8.0

Generic name: alirocumab systemic

Brand name:  Praluent

Drug class: PCSK9 inhibitors

For consumers: dosage,

For professionals: A-Z Drug Facts, AHFS DI Monograph

FloLipid X N Add review Rate

Generic name: simvastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

fluvastatin X N Add review Rate

Generic name: fluvastatin systemic

Brand names:  Lescol, Lescol XL

Drug class: statins

For consumers: dosage, interactions,

For professionals: A-Z Drug Facts, AHFS DI Monograph, Prescribing Information

Lescol X N Add review Rate

Generic name: fluvastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

For professionals: AHFS DI Monograph, Prescribing Information

Lescol XL X N Add review Rate

Generic name: fluvastatin systemic

Drug class: statins

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Repatha Pushtronex N 1 review
6.0

Generic name: evolocumab systemic

Drug class: PCSK9 inhibitors

For consumers: dosage, side effects

Repatha SureClick N Add review Rate

Generic name: evolocumab systemic

Drug class: PCSK9 inhibitors

For consumers: dosage,

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Learn more about High Cholesterol, Familial Heterozygous

Drugs.com Health Center

Legend

Off Label This medication may not be approved by the FDA for the treatment of this condition.
Prescription Only / Over the Counter
Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Pregnancy
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

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