Repatha Alternatives Compared
| Repatha | Atorvastatin | Simvastatin |
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| Repatha (evolocumab) | Atorvastatin | Simvastatin |
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Prescription only
Repatha is a PCSK9 inhibitor that may be used to reduce LDL-C levels in people with primary hyperlipidemia and HoFH, and also to reduce the risk of cardiovascular events in adults with established... View more |
Prescription only
Atorvastatin is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. Prescribed for High Cholesterol, High Cholesterol - Familial Heterozygous... View more |
Prescription only
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain particularly at higher dosages. Prescribed for Cardiovascular Risk Reduction, High Cholesterol - Familial... View more |
Related suggestions High Cholesterol
High Cholesterol, Familial Heterozygous
High Cholesterol, Familial Homozygous
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| More about Repatha (evolocumab) | More about Atorvastatin | More about Simvastatin | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
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No lower-cost generic available |
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| Ratings & Reviews | ||||||||||||||||||||||||||
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Repatha has an average rating of 4.8 out of 10 from a total of 565 ratings on Drugs.com. 36% of reviewers reported a positive effect, while 53% reported a negative effect. |
Atorvastatin has an average rating of 4.3 out of 10 from a total of 296 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 56% reported a negative effect. |
Simvastatin has an average rating of 4.8 out of 10 from a total of 131 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 49% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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See also: Repatha side effects in more detail. |
See also: atorvastatin side effects in more detail. |
See also: simvastatin side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Repatha prices |
View all atorvastatin prices |
View all simvastatin prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Atorvaliq, Lipitor | FloLipid, Zocor | ||||||||||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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408 hours |
14 hours |
N/A |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 2 drugs are known to interact with Repatha:
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A total of 368 drugs are known to interact with atorvastatin:
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A total of 304 drugs are known to interact with simvastatin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||||||||||
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August 27, 2015 |
December 17, 1996 |
December 23, 1991 |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.