Repatha Alternatives Compared
| Repatha (evolocumab) | Ozempic (semaglutide) | Simvastatin |
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| Repatha (evolocumab) | Ozempic (semaglutide) | Simvastatin |
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Prescription only
Repatha is a PCSK9 inhibitor that may be used to reduce LDL-C levels in people with primary hyperlipidemia and HoFH, and also to reduce the risk of cardiovascular events in adults with established... View more |
Prescription only
Ozempic lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is... View more |
Prescription only
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain, particularly at higher dosages. Should not be used by people with active liver disease or in women planning a... View more |
Related suggestions Cardiovascular Risk Reduction
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| More about Repatha (evolocumab) | More about Ozempic (semaglutide) | More about Simvastatin | ||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Repatha has an average rating of 5.4 out of 10 from a total of 713 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 44% reported a negative effect. |
Ozempic has an average rating of 6.7 out of 10 from a total of 1561 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 23% reported a negative effect. |
Simvastatin has an average rating of 4.8 out of 10 from a total of 131 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 48% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||||||
View all Repatha side effects |
View all Ozempic side effects |
View all Simvastatin side effects |
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| Drug Class | ||||||||||||||||||||||||||
| Generic Availability | ||||||||||||||||||||||||||
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N/A |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Repatha prices |
View all Ozempic prices |
View all Simvastatin prices |
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| Dosage Forms | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
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N/A |
Other semaglutide brands include: Rybelsus, Wegovy | FloLipid, Zocor | ||||||||||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||||||||||
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408 hours |
168 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 3 drugs are known to interact with Repatha:
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A total of 274 drugs are known to interact with Ozempic:
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A total of 337 drugs are known to interact with Simvastatin:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | ||||||||||||||||||||||||||
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August 27, 2015 |
N/A |
December 23, 1991 |
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| WADA Class View classifications | ||||||||||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||||||||||
| Patient Resources | ||||||||||||||||||||||||||
| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Lipitor
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Crestor
Crestor (rosuvastatin) is used to treat high cholesterol and high triglycerides in the blood ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Zetia
Zetia (ezetimibe) is used to treat high cholesterol. Includes Zetia side effects, interactions and ...
Zocor
Zocor (simvastatin) reduces low-density lipoprotein cholesterol and total cholesterol in the blood ...
Praluent
Praluent (alirocumab) is an injectable medicine that is given under your skin which may be used in ...
Lovastatin
Lovastatin is used for high cholesterol, high cholesterol, familial heterozygous ...
Pravastatin
Pravastatin (Pravachol) is a statin medicine used to lower cholesterol and triglycerides in the ...
Simvastatin
Simvastatin (Zocor) is a cholesterol-lowering medication that blocks the production of cholesterol ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.