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Leqvio and Headaches: What Users Say

Headaches: mentioned by 4 users (4.9%)

Based on user experiences from 82 Leqvio reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

muscle pain 13.4%
pain 12.2%
joint pain 8.5%
fatigue 7.3%
burning 6.1%
cramps 6.1%
stiffness 6.1%
headaches 4.9%
itching 4.9%
muscle aches 4.9%

Reviews for Leqvio

Showing 4 reviews tagged with "headaches". Clear filters to view all 82 reviews.
Commonly mentioned side effects
  • K-T...
  • Taken for 1 to 6 months
  • August 15, 2024

For High Cholesterol "Just had 2nd injection…side effects abound (headache, nausea, muscle weakness and pain, low backache, constipation, ridiculous levels of fatigue, and much more) and never fully dissipated after 1st injection…fully started up again with this injection…all are annoying and affect quality of life…arthritis pain in hands and feet, and cramping in feet, legs, hands are among the worst along with the continual migraine. The medication definitely dramatically lowered my LDL…just not sure I want to continue."

9 / 10
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43 Report
  • fem...
  • Taken for less than 1 month
  • April 19, 2025

For High Cholesterol, Familial Heterozygous "First of all, I see a functional dietitian. Following a strict diet, regular exercise, and taking magnesium, vitamin D, vitamin K, I was able to drop 20 lbs in a year. My starting cholesterol was 315 and with a low-fat, no seed oil, higher protein diet, I was able to get my cholesterol down to 235. My LDL-C was 170. CA score of 165. So here I am, I had my first shot of Leqvio. Side effects are exhaustion, headaches, and foot and hand cramps. Extra water and magnesium seem to help."

5 / 10
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0 Report
  • Anonymous
  • Taken for 1 to 6 months
  • May 8, 2023

For High Cholesterol "Side effects, hives, itching, pain with urination, headaches, dizziness, blurred vision, and sweating."

1 / 10
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69 Report

Frequently asked questions

  • San...
  • September 4, 2024

For High Cholesterol "Two weeks after the first injection, I developed pain in my hips, lower back, ankles, feet, hands, including toes and fingers, burning with urination, burning in my eyes, fatigue, and headaches."

2 / 10
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15 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.