Generic Name: rosuvastatin (roe SOO va sta tin)
Brand Name: Crestor, Ezallor Sprinkle
What is rosuvastatin?
Rosuvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).
Rosuvastatin is used in adults and children who are at least 8 years old, to lower cholesterol and triglycerides (types of fat) in the blood and to slow the build-up of plaque (fatty deposits) in blood vessels.
Rosuvastatin is also used to treat hereditary forms of high cholesterol, including the heterozygous type (inherited from one parent) and the homozygous type (inherited from both parents). For the heterozygous type, rosuvastatin can be used in children who are at least 8 years old. For the homozygous type, rosuvastatin can be used in children as young as 7 years old.
Rosuvastatin is also used to lower the risk of stroke, heart attack, and certain other heart complications in men 50 years and older and women 60 years and older who have risk factors for heart disease.
Rosuvastatin may also be used for purposes not listed in this medication guide.
Do not use rosuvastatin if you are pregnant. It could harm the unborn baby.
You should not take rosuvastatin if you have liver disease, or if you breast-feeding a baby.
Before taking this medicine
You should not take rosuvastatin if you are allergic to it, or if you have:
liver disease; or
if you are pregnant or breast-feeding.
Do not take rosuvastatin if you are pregnant. It could harm the unborn baby. Use effective birth control to prevent pregnancy while you are taking rosuvastatin. Stop taking rosuvastatin and tell your doctor right away if you become pregnant.
Rosuvastatin may pass into breast milk and could harm a nursing baby. Do not breast-feed while you are taking rosuvastatin.
Tell your doctor if you have ever had:
a thyroid disorder;
a habit of drinking more than 2 alcoholic beverages per day;
if you are of Asian descent; or
if you are 65 or older.
Rosuvastatin can cause the breakdown of muscle tissue, which can lead to kidney failure. This happens more often in women, in older adults, or people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid).
People of Asian descent may absorb rosuvastatin at a higher rate than other people. Make sure your doctor knows if you are Asian. You may need a lower than normal starting dose.
How should I take rosuvastatin?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.
Rosuvastatin is usually taken once a day, with or without food. Take the medicine at the same time each day.
While using rosuvastatin, you may need frequent blood tests.
Keep using rosuvastatin as directed, even if you feel well. High cholesterol usually has no symptoms. You may need to take rosuvastatin on a long-term basis.
You may need to stop using rosuvastatin for a short time if you have:
an electrolyte imbalance (such as high or low potassium levels in your blood);
severely low blood pressure;
a severe infection or illness;
surgery or a medical emergency.
You should not stop using rosuvastatin unless your doctor tells you to.
Rosuvastatin is only part of a treatment program that may also include diet, exercise, and weight control. Follow your doctor's instructions very closely.
Store at room temperature away from moisture, heat, and light.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if you are more than 12 hours late for the dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking rosuvastatin?
Avoid eating foods high in fat or cholesterol, or rosuvastatin will not be as effective.
Avoid drinking alcohol. It can raise triglyceride levels and may increase your risk of liver damage.
Some antacids can make it harder for your body to absorb rosuvastatin. Avoid taking an antacid that contains aluminum or magnesium within 2 hours after taking rosuvastatin.
Rosuvastatin side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
unexplained muscle pain, tenderness, or weakness;
confusion, memory problems; or
liver problems--upper stomach pain, tired feeling, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes).
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect rosuvastatin?
Using certain other drugs together with rosuvastatin can increase your risk of serious muscle problems. It is very important to tell your doctor about all medicines you use, and those you start or stop using during your treatment with rosuvastatin, especially:
This list is not complete. Other drugs may affect rosuvastatin, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Copyright 1996-2018 Cerner Multum, Inc. Version: 12.01.
More about rosuvastatin
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Patient Tips
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 139 Reviews
- Drug class: statins
- FDA Alerts (2)