Simvastatin Interactions
There are 336 drugs known to interact with simvastatin, along with 6 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 60 are major, 264 are moderate, and 12 are minor.
- View all 336 medications that may interact with simvastatin
- View simvastatin alcohol/food interactions (2)
- View simvastatin disease interactions (6)
Most frequently checked interactions
View interaction reports for simvastatin and the medicines listed below.
- Advair Diskus (fluticasone / salmeterol)
- Aspir 81 (aspirin)
- Aspirin Low Strength (aspirin)
- Calcium 600 D (calcium / vitamin d)
- CoQ10 (ubiquinone)
- Cymbalta (duloxetine)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Januvia (sitagliptin)
- Lantus (insulin glargine)
- Lasix (furosemide)
- Lexapro (escitalopram)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Tartrate (metoprolol)
- MiraLAX (polyethylene glycol 3350)
- Nexium (esomeprazole)
- Norco (acetaminophen / hydrocodone)
- Plavix (clopidogrel)
- ProAir HFA (albuterol)
- Singulair (montelukast)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Zoloft (sertraline)
- Zyrtec (cetirizine)
Simvastatin alcohol/food interactions
There are 2 alcohol/food interactions with simvastatin.
Simvastatin disease interactions
There are 6 disease interactions with simvastatin which include:
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.