Comparing Lipitor vs Simvastatin
| Lipitor (atorvastatin) | Simvastatin |
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| Lipitor (atorvastatin) | Simvastatin |
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Prescription only
Lipitor is effective at lowering cholesterol; however, its use may be limited by side effects such as muscle pain. Prescribed for High Cholesterol - Familial Homozygous, High Cholesterol - Familial... View more |
Prescription only
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain, particularly at higher dosages. Should not be used by people with active liver disease or in women planning a... View more |
Related suggestions High Cholesterol, Familial Heterozygous
High Cholesterol, Familial Homozygous
Prevention of Cardiovascular Disease
Hyperlipoproteinemia
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| More about Lipitor (atorvastatin) | More about Simvastatin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Lipitor has an average rating of 4.3 out of 10 from a total of 102 ratings on Drugs.com. 28% of reviewers reported a positive effect, while 54% reported a negative effect. |
Simvastatin has an average rating of 4.8 out of 10 from a total of 131 ratings on Drugs.com. 30% of reviewers reported a positive effect, while 48% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Lipitor side effects |
View all Simvastatin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Lipitor prices |
View all Simvastatin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other atorvastatin brands include: Atorvaliq | FloLipid, Zocor | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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14 hours |
N/A |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 403 drugs are known to interact with Lipitor:
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A total of 334 drugs are known to interact with Simvastatin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 17, 1996 |
December 23, 1991 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.