Comparing Pravastatin vs Simvastatin
| Pravastatin | Simvastatin |
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| Pravastatin | Simvastatin |
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Prescription only
Pravastatin is effective at lowering cholesterol; however, it may not be as effective as atorvastatin. Grapefruit products do not affect pravastatin to the same extent as atorvastatin. Prescribed for... View more |
Prescription only
Simvastatin is effective at lowering cholesterol; however, it may cause muscle pain, particularly at higher dosages. Should not be used by people with active liver disease or in women planning a... View more |
Related suggestions High Cholesterol
High Cholesterol, Familial Heterozygous
Hyperlipoproteinemia
Hyperlipoproteinemia Type IIa, Elevated LDL
Popular comparisons
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| More about Pravastatin | More about Simvastatin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Pravastatin has an average rating of 4.5 out of 10 from a total of 77 ratings on Drugs.com. 25% of reviewers reported a positive effect, while 49% reported a negative effect. |
Simvastatin has an average rating of 4.9 out of 10 from a total of 131 ratings on Drugs.com. 32% of reviewers reported a positive effect, while 49% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Pravastatin prices |
View all Simvastatin prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
FloLipid, Zocor | ||||||||||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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3 hours |
N/A |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 190 drugs are known to interact with Pravastatin:
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A total of 331 drugs are known to interact with Simvastatin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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October 31, 1991 |
December 23, 1991 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.