Phenobarbital Alternatives Compared
| Phenobarbital | Xcopri (cenobamate) | Keppra (levetiracetam) |
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| Phenobarbital | Xcopri (cenobamate) | Keppra (levetiracetam) |
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Prescription only
Prescribed for Epilepsy, Insomnia, Hyperbilirubinemia, Sedation, Seizures. Phenobarbital may also be used for purposes not listed in this medication guide. |
Prescription only
Xcopri (cenobamate) treats partial-onset seizures in adults. Common side effects include clumsiness, dizziness, drowsiness, double vision, uncontrolled eye movements, headache, and vertigo. Less... View more |
Prescription only
Keppra is an anticonvulsant used to treat partial onset, myoclonic, or generalized tonic-clonic seizures, either alone or in combination with other anticonvulsants. It may cause drowsiness but is... View more |
Related suggestionsSeizuresPopular Comparisons |
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| More about Phenobarbital | More about Xcopri (cenobamate) | More about Keppra (levetiracetam) | ||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||
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Phenobarbital has an average rating of 8.9 out of 10 from a total of 44 ratings on Drugs.com. 89% of reviewers reported a positive effect, while 7% reported a negative effect. |
Xcopri has an average rating of 8.0 out of 10 from a total of 71 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 4% reported a negative effect. |
Keppra has an average rating of 5.7 out of 10 from a total of 318 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 34% reported a negative effect. |
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View all 44 reviews |
View all 71 reviews |
View all 318 reviews |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||||||
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View all side effects |
View all side effects |
View all side effects |
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| Boxed Warnings A boxed warning is the most serious warning from the Food and Drug Administration (FDA) about drug effects that may be dangerous. | ||||||||||||||||||||||
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View boxed warnings |
N/A |
N/A |
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| Generic Availability Learn more about brand vs generic drugs. | ||||||||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance. | ||||||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||
| Sezaby |
N/A |
Other levetiracetam brands include: Elepsia XR, Keppra XR, Roweepra, Roweepra XR, Spritam | ||||||||||||||||||||
| Half Life Learn about the half-life of a drug and how it is calculated. | ||||||||||||||||||||||
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118 hours |
60 hours |
8 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||
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Category D
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||
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A total of 851 drugs are known to interact with Phenobarbital:
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A total of 611 drugs are known to interact with Xcopri:
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A total of 243 drugs are known to interact with Keppra:
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| First Approval Date | ||||||||||||||||||||||
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N/A |
November 21, 2019 |
November 30, 1999 |
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| WADA Class View classifications | ||||||||||||||||||||||
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| Related Treatment Guide | ||||||||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.