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Comparing Oxybutynin vs Tolterodine

View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.
Oxybutynin Remove Oxybutynin from your drug comparison Tolterodine Remove Tolterodine from your drug comparison
View side-by-side comparisons of medication uses, ratings, cost, side effects, interactions and more.
Oxybutynin Remove Oxybutynin from your drug comparison Tolterodine Remove Tolterodine from your drug comparison

Oxybutynin helps to relieve symptoms of an overactive bladder and urinary incontinence but it may cause side effects such as dry mouth and constipation. Prescribed for Overactive Bladder, Urinary... View more

Prescribed for Overactive Bladder, Urinary Incontinence. tolterodine may also be used for purposes not listed in this medication guide.

Prescription and OTC

Prescription only

Ratings & Reviews

Recent helpful reviews
6.6
282 Reviews

For Overactive Bladder: I have been taking 5mg oxybutynin twice a day for about a month now for my overactive bladder. I’m 55. I have sporadic stomach pain, bloating, dry mouth, dry eyes. I’m concerned about the stomach pain and wonder if I should stop taking the medicine. It has helped me going from 6 trips to the bathroom to about 3. Any feedback about my stomach pain is appreciated.

6

For Overactive Bladder: I've been on it now for 7 days the heart burn is bad, a little dry mouth, my frequency is slowed down a bit gonna stay on it fir a lil while longer. Sometimes I pee a lil more, somedays less but thats my anxiety that triggers it to as my nerves are a lil on edge but - thats just me. I'm hoping in time it does help me ....

6
6.4
54 Reviews

For Overactive Bladder: I have been on this med for a week now. The first couple days were horrible, headaches, fatigue and overall felt like a walking zombie, and on top of that the drug didn't kick in until three days in. Day 7 now and the drug has started working. I do not feel the overwhelming urge to pee myself during the day which is wonderful. But I have my first appointment since starting it now and I have to decide if the fatigue is worth it.

6

For Overactive Bladder: I have been on tolterodine for about 9 days now and I haven't had the embarrassing accidents but during the day I still go a lot but not as often. On the other hand I am getting more sleep only getting up once compared to 5 times as I was use to. I do get mild headaches and really dry mouth but it is worth it to not have to locate the nearest facility every where I go.

5

View all 282 reviews

View all 54 reviews

Drug Class

Side Effects

Commonly reported side effects include: constipation, drowsiness, and local pruritus.

See the full oxybutynin side effects document.

Commonly reported side effects include: xerostomia.

See the full tolterodine side effects document.

Pricing and Coupons

* Prices are without insurance
Quantity 100 each
Dosage 5 mg
Per Unit* $0.45
Cost* $45.32

View all oxybutynin prices

Quantity 30 each
Dosage 2 mg
Per Unit* $8.72 - $9.77
Cost* $261.55 - $293.13

View all tolterodine prices

Get free Discount Card

Get free Discount Card

Generic Availability

Yes (this medicine)

Yes (this medicine)

Dosage Form(s) Available
  • Oral syrup
  • Oral tablet
  • Oral tablet, extended release
  • Oral capsule, extended release
  • Oral tablet

Brand Names
Anturol, Ditropan, Ditropan XL, Gelnique, Oxytrol, Oxytrol for Women, Urotrol Detrol, Detrol LA

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

2.3 hours

3.7 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category
B
Category B No proven risk in humans

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (1)

N/A

Drug Interactions

A total of 665 drugs are known to interact with oxybutynin:

  • 14 major drug interactions (85 brand and generic names)
  • 567 moderate drug interactions (3932 brand and generic names)
  • 84 minor drug interactions (736 brand and generic names)

A total of 727 drugs are known to interact with tolterodine:

  • 14 major drug interactions (85 brand and generic names)
  • 587 moderate drug interactions (3689 brand and generic names)
  • 126 minor drug interactions (947 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Ask your doctor before using oxybutynin together with alcohol. Use alcohol cautiously. Alcohol... View more
  • Ask your doctor before using tolterodine together with alcohol. Use alcohol cautiously. Alcohol... View more

Disease Interactions

First Approval Date

July 16, 1975

March 25, 1998

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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