Tolterodine Dosage
Medically reviewed by Drugs.com. Last updated on Jul 16, 2024.
Applies to the following strengths: 1 mg; 2 mg; 4 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Urinary Incontinence
Immediate release tablets:
- Initial dose: 2 mg orally 2 times a day
- Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability
Extended release capsules:
- Initial dose: 4 mg orally once a day
- Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability
Comments:
- This drug can be taken with or without food.
- The extended release formulation should be swallowed whole.
Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency
Usual Adult Dose for Urinary Frequency
Immediate release tablets:
- Initial dose: 2 mg orally 2 times a day
- Maintenance dose: 1 to 2 mg orally 2 times a day, depending on patient response and tolerability
Extended release capsules:
- Initial dose: 4 mg orally once a day
- Maintenance dose: 2 to 4 mg orally once a day, depending on patient response and tolerability
Comments:
- This drug can be taken with or without food.
- The extended release formulation should be swallowed whole.
Use: For the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and frequency
Renal Dose Adjustments
- Severe renal impairment (CrCl 10 to 30 mL/min):
Extended release capsules: 2 mg orally once a day
- End stage renal disease (CrCl less than 10 mL/min):
Liver Dose Adjustments
- Mild to moderate hepatic impairment (Child-Pugh Class A or B):
Extended release formulation: 2 mg orally 2 times a day
- Severe hepatic impairment (Child-Pugh Class C):
Dose Adjustments
Concomitant use of potent CYP450 3A4 inhibitors:
Immediate release formulation: 1 mg orally 2 times a day
Extended release formulation: 2 mg orally once a day
Precautions
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration advice:
- This drug can be taken with or without food.
General:
- Treatment effect should be reevaluated after 2 to 6 months.
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Patient resources
- Tolterodine drug information
- Tolterodine (Advanced Reading)
- Tolterodine Tablets
- Tolterodine Extended-Release Capsules
Other brands
Professional resources
- Tolterodine monograph
- Tolterodine Tartrate Capsules (FDA)
- Tolterodine Tartrate ER Tablets (FDA)
- Tolterodine Tartrate Tablets (FDA)
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
