Niacin Alternatives Compared
| Niacin | Bupropion | Sertraline |
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| Niacin | Bupropion | Sertraline |
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Prescription and OTC
Prescribed for High Cholesterol, Depression, Dietary Supplementation, Pellagra, Niacin Deficiency, Hyperlipoproteinemia, Hyperlipoproteinemia Type IV - Elevated VLDL, Hyperlipoproteinemia Type V -... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Prescription only
Sertraline is an effective antidepressant with less potential for drowsiness than other antidepressants. Headaches, nausea, diarrhea, weight loss, insomnia, tremors, and sexual dysfunction are the... View more |
Related suggestions Depression
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| More about Niacin | More about Bupropion | More about Sertraline | ||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||
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Niacin has an average rating of 7.4 out of 10 from a total of 117 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 20% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2913 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 20% reported a negative effect. |
Sertraline has an average rating of 7.3 out of 10 from a total of 4585 ratings on Drugs.com. 64% of reviewers reported a positive effect, while 18% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||||||||||||||||||
View all Niacin side effects |
View all Bupropion side effects |
View all Sertraline side effects |
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| Drug Class | ||||||||||||||||||
| Generic Availability | ||||||||||||||||||
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Lower cost generic |
Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Bupropion prices |
View all Sertraline prices |
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| Dosage Forms | ||||||||||||||||||
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| Brand Names | ||||||||||||||||||
| B-3-50, B3-500-Gr, Endur-acin, HDL Benefit, Heliocare Advanced, Niacin SR, Niacor, Niaspan, NiaVasc, Slo-Niacin, Vitamin B3 View more | Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | Zoloft | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||||||||||||||||||
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1 hour |
30 hours |
66 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||
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A total of 107 drugs are known to interact with Niacin:
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A total of 560 drugs are known to interact with Bupropion:
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A total of 673 drugs are known to interact with Sertraline:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||
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| Disease Interactions | ||||||||||||||||||
| First Approval Date | ||||||||||||||||||
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July 24, 1957 |
December 30, 1985 |
December 30, 1991 |
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| WADA Class View classifications | ||||||||||||||||||
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N/A |
N/A |
N/A |
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| More Information | ||||||||||||||||||
| Patient Resources | ||||||||||||||||||
| Professional Resources | ||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||
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1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.