Comparing Methadone vs Oxycodone
Methadone | Oxycodone |
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Methadone | Oxycodone |
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Prescription only
Methadone is a potent opioid analgesic that may be used to relieve severe pain unresponsive to other strong pain relievers; however, it is more commonly used to treat opioid addiction. There is a... View more |
Prescription only
Oxycodone is a semisynthetic opioid medication with potent pain-relieving properties that may be used to relieve severe pain that is unresponsive to less potent pain-relieving medicines (analgesics)... View more |
Related suggestions Chronic Pain
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More about Methadone | More about Oxycodone | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Methadone has an average rating of 8.7 out of 10 from a total of 599 ratings on Drugs.com. 85% of reviewers reported a positive effect, while 5% reported a negative effect. |
Oxycodone has an average rating of 6.9 out of 10 from a total of 1133 ratings on Drugs.com. 63% of reviewers reported a positive effect, while 25% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: methadone side effects in more detail. |
See also: oxycodone side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all methadone prices |
View all oxycodone prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Methadone Diskets, Methadose, Methadose Sugar-Free | Dazidox, Endocodone, ETH-Oxydose, Oxaydo, OxyContin, Oxydose, Oxyfast, Roxicodone, RoxyBond, Xtampza ER View more | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
30 hours |
5.6 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 726 drugs are known to interact with methadone:
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A total of 594 drugs are known to interact with oxycodone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
August 13, 1947 |
October 26, 1998 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.