Comparing Metaxalone vs Tizanidine
| Metaxalone | Tizanidine |
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| Metaxalone | Tizanidine |
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Prescription only
Metaxalone is a muscle relaxant that appears to exert its effects through sedation. Taking metaxalone with food can increase its absorption and enhance its effects (such as sedation). Seniors may be... View more |
Prescription only
Tizanidine may be used to reduce muscle spasms but common side effects include sleepiness, a drop in blood pressure, and a dry mouth. The dosage of tizanidine should be tailored to each person and... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
Popular comparisons
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| More about Metaxalone | More about Tizanidine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Metaxalone has an average rating of 7.0 out of 10 from a total of 126 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 21% reported a negative effect. |
Tizanidine has an average rating of 6.2 out of 10 from a total of 386 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 29% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Metaxalone side effects |
View all Tizanidine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Metaxalone prices |
View all Tizanidine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Metaxal, Metaxall, Skelaxin | Ontralfy, Zanaflex | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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3 hours |
2.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 318 drugs are known to interact with Metaxalone:
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A total of 654 drugs are known to interact with Tizanidine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 13, 1962 |
November 27, 1996 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.