Metaxalone Dosage

Medically reviewed by Drugs.com. Last updated on Mar 29, 2024.

Usual Adult Dose for Muscle Spasm

Recommended dosage: 800 mg orally 3 to 4 times a day

Use: Painful musculoskeletal conditions as an adjunct to rest, physical therapy, and other measures

Usual Pediatric Dose for Muscle Spasm

Children 12 years and older:
Recommended dosage: 800 mg orally 3 to 4 times a day

Use: Painful musculoskeletal conditions as an adjunct to rest, physical therapy, and other measures in patients 12 years of age and older

Renal Dose Adjustments

Mild to moderate renal dysfunction: Use with caution
Severe renal dysfunction: Contraindicated

Liver Dose Adjustments

Mild to moderate liver dysfunction: Use with caution
Severe liver dysfunction: Contraindicated

Precautions

CONTRAINDICATIONS:

• Hypersensitivity to the active component or any of the ingredients
• Known tendency to drug induced, hemolytic, or other anemias
• Severe renal or hepatic dysfunction

Safety and efficacy have not been established in patients younger than 12 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• Can be taken with or without food.

Storage requirements:

• Store at 20C to 25C (68F to 77F), with excursions permitted to 15C to 30C (59F to 86F)

General:

• Deaths by deliberate or accidental overdose have occurred with this drug, particularly in combination with antidepressants, and in combination with alcohol.

Monitoring:

• CNS symptoms and signs of serotonin syndrome, respiratory depression, or excessive sedation
• Report suspected adverse reactions to www.fda.gov/medwatch

Patient advice:

• Read the Patient Information and Instructions for Use.
• This drug may impair mental and/or physical abilities required for performance of hazardous tasks, such as operating machinery or driving a motor vehicle, especially when used with alcohol or other CNS depressants.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer