Comparing Flexeril vs Metaxalone
| Flexeril (cyclobenzaprine) | Metaxalone |
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| Flexeril (cyclobenzaprine) | Metaxalone |
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Prescription only
Flexeril is a muscle relaxant that may be used short-term in addition to rest and physical therapy to treat muscle spasms caused by musculoskeletal conditions. Sedation is a common side effect... View more |
Prescription only
Metaxalone is a muscle relaxant that appears to exert its effects through sedation. Taking metaxalone with food can increase its absorption and enhance its effects (such as sedation). Seniors may be... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
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| More about Flexeril (cyclobenzaprine) | More about Metaxalone | ||||||||
| Ratings & Reviews | |||||||||
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Flexeril has an average rating of 6.1 out of 10 from a total of 239 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 27% reported a negative effect. |
Metaxalone has an average rating of 7.0 out of 10 from a total of 126 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 21% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Flexeril side effects |
View all Metaxalone side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Metaxalone prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Other cyclobenzaprine brands include: Amrix, Comfort Pac with Cyclobenzaprine | Metaxal, Metaxall, Skelaxin | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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72 hours |
3 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 453 drugs are known to interact with Flexeril:
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A total of 318 drugs are known to interact with Metaxalone:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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August 26, 1977 |
August 13, 1962 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.