Comparing Flexeril vs Tizanidine
| Flexeril | Tizanidine |
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| Flexeril (cyclobenzaprine) | Tizanidine |
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Prescription only
Flexeril is a muscle relaxant that may be used short-term in addition to rest and physical therapy to treat muscle spasms caused by musculoskeletal conditions. Sedation is a common side effect... View more |
Prescription only
Tizanidine relieves muscle spasms but may cause sleepiness, a drop in blood pressure, and sedation. The dosage should be individualized and because it only lasts for a short time in the body, can be... View more |
Related suggestions Muscle Spasm (Involuntary Hypertonicity)
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| More about Flexeril (cyclobenzaprine) | More about Tizanidine | ||||||||
| Generic Status | |||||||||
| Ratings & Reviews | |||||||||
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Flexeril has an average rating of 6.0 out of 10 from a total of 236 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 28% reported a negative effect. |
Tizanidine has an average rating of 6.1 out of 10 from a total of 375 ratings on Drugs.com. 48% of reviewers reported a positive effect, while 30% reported a negative effect. |
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| Drug Class | |||||||||
| Side Effects | |||||||||
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See also: Flexeril side effects in more detail. |
See also: tizanidine side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all tizanidine prices |
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| Dosage Form(s) Available | |||||||||
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N/A |
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| Brand Names | |||||||||
| Other cyclobenzaprine brands include: Amrix, Comfort Pac with Cyclobenzaprine | Zanaflex | ||||||||
| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||
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72 hours |
2.5 hours |
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| CSA Schedule ** View glossary of terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 431 drugs are known to interact with Flexeril:
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A total of 601 drugs are known to interact with tizanidine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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August 26, 1977 |
November 27, 1996 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.