Comparing Leflunomide vs Sulfasalazine
| Leflunomide | Sulfasalazine |
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| Leflunomide | Sulfasalazine |
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Prescription only
Prescribed for Rheumatoid Arthritis, Psoriatic Arthritis. Leflunomide may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Alopecia, Crohn's Disease, Crohn's Disease - Maintenance, Juvenile Rheumatoid Arthritis, Lymphocytic Colitis, Inflammatory Bowel Disease, Crohn's Disease - Active, Psoriatic Arthritis... View more |
Related suggestions Rheumatoid Arthritis
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| More about Leflunomide | More about Sulfasalazine | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Leflunomide has an average rating of 5.1 out of 10 from a total of 115 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 46% reported a negative effect. |
Sulfasalazine has an average rating of 6.0 out of 10 from a total of 198 ratings on Drugs.com. 46% of reviewers reported a positive effect, while 33% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Leflunomide side effects |
View all Sulfasalazine side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Leflunomide prices |
View all Sulfasalazine prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Arava | Azulfidine, Azulfidine EN-tabs | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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336 hours |
10 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 680 drugs are known to interact with Leflunomide:
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A total of 269 drugs are known to interact with Sulfasalazine:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 10, 1998 |
June 20, 1950 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.