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Leflunomide use while Breastfeeding

Drugs containing Leflunomide: Arava

Medically reviewed by Drugs.com. Last updated on Feb 13, 2021.

Leflunomide Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the use of leflunomide during breastfeeding, so an alternate drug may be preferred, especially while nursing a newborn or preterm infant.[1][2]

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

(Rheumatoid Arthritis) Auranofin, Gold Sodium Thiomalate, Hydroxychloroquine, Infliximab, Methotrexate, Penicillamine, Sulfasalazine

References

1.
Sammaritano LR, Bermas BL. Rheumatoid arthritis medications and lactation. Curr Opin Rheumatol. 2014;26:354-60. [PubMed: 24614280]
2.
Flint J, Panchal S, Hurrell A et al. BSR and BHPR guideline on prescribing drugs in pregnancy and breastfeeding-Part I: standard and biologic disease modifying anti-rheumatic drugs and corticosteroids. Rheumatology (Oxford). 2016;55:1693-7. [PubMed: 26750124]

Substance Identification

Substance Name

Leflunomide

CAS Registry Number

75706-12-6

Drug Class

  • Breast Feeding
  • Lactation
  • Antirheumatic Agents
  • Immunosuppressive Agents

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Further information

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