Leflunomide Interactions
There are 681 drugs known to interact with leflunomide, along with 7 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 549 are major, 122 are moderate, and 10 are minor.
- View all 681 medications that may interact with leflunomide
- View leflunomide alcohol/food interactions (2)
- View leflunomide disease interactions (7)
Most frequently checked interactions
View interaction reports for leflunomide and the medicines listed below.
- Celebrex (celecoxib)
- Celebrex (celecoxib)
- Cymbalta (duloxetine)
- Cymbalta (duloxetine)
- Enbrel (etanercept)
- Enbrel (etanercept)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Humira (adalimumab)
- Humira (adalimumab)
- Lyrica (pregabalin)
- Lyrica (pregabalin)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Succinate ER (metoprolol)
- Orencia (abatacept)
- Orencia (abatacept)
- Plaquenil (hydroxychloroquine)
- Plaquenil (hydroxychloroquine)
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D2 (ergocalciferol)
- Vitamin D2 (ergocalciferol)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Leflunomide alcohol/food interactions
There are 2 alcohol/food interactions with leflunomide.
Leflunomide disease interactions
There are 7 disease interactions with leflunomide which include:
- immunosuppression
- liver disease
- peripheral neuropathy
- pulmonary toxicity
- renal dysfunction
- tuberculosis
- hypertension
Report options
More about leflunomide
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- Reviews (116)
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- Side effects
- Dosage information
- During pregnancy
- Drug class: antirheumatics
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Humira
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Plaquenil
Plaquenil is used to treat or prevent malaria and to treat the symptoms of rheumatoid arthritis ...
Skyrizi
Skyrizi (risankizumab) is used to treat plaque psoriasis, psoriatic arthritis, ulcerative colitis ...
Enbrel
Enbrel is used to treat rheumatoid arthritis, ankylosing spondylitis, and psoriasis. Learn about ...
Remicade
Remicade is used to treat rheumatoid arthritis, psoriatic arthritis, ulcerative colitis and Crohn's ...
Rituxan
Rituxan infusion is used to treat certain leukemias and lymphomas and some non-cancer conditions ...
Orencia
Orencia is a type of biologic that is given by intravenous infusion or subcutaneous injection which ...
Infliximab
Infliximab infusion (brand names Avsola, Inflectra, Remicade, and others) reduces inflammation and ...
Rituximab
Rituximab infusion is used to treat certain leukemias and lymphomas and some non-cancer conditions ...
Adalimumab
Adalimumab is used to treat plaque psoriasis, Crohn's disease, ulcerative colitis, rheumatoid ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
