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Leflunomide and Alcohol / Food Interactions

There are 2 alcohol/food/lifestyle interactions with leflunomide which include:


leflunomide ↔ food

Moderate Food Interaction

Leflunomide can be taken with or without food. It is important to take leflunomide regularly to get the most benefit. Discuss with your doctor the use of alcohol while taking leflunomide. Alcohol and leflunomide can both be damaging to the liver.

Switch to professional interaction data


High Blood Pressure (Hypertension)

Moderate Potential Hazard, Moderate plausibility

leflunomide - hypertension

Hypertension was reported as an adverse reaction in patients on leflunomide. Blood pressure should be monitored during treatment and periodically thereafter as this agent can increase the blood pressure in these patients.

Leflunomide drug interactions

There are 774 drug interactions with leflunomide

Leflunomide disease interactions

There are 7 disease interactions with leflunomide which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.