Klonopin Alternatives Compared
Klonopin | Onfi | Epidiolex |
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Klonopin (clonazepam) | Onfi (clobazam) | Epidiolex (cannabidiol) |
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Prescription only
Klonopin may be used in the treatment of panic disorder and certain types of seizure disorder. Sedation is the most common side effect and it can cause both physical and psychological dependence... View more |
Prescription only
Prescribed for Lennox-Gastaut Syndrome. Onfi may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Lennox-Gastaut Syndrome, Dravet Syndrome, Tuberous Sclerosis Complex. Epidiolex may also be used for purposes not listed in this medication guide. |
Related suggestions |
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More about Klonopin (clonazepam) | More about Onfi (clobazam) | More about Epidiolex (cannabidiol) | ||||||||||||||||||||||||
Generic Status | ||||||||||||||||||||||||||
No lower-cost generic available |
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Ratings & Reviews | ||||||||||||||||||||||||||
Klonopin has an average rating of 8.5 out of 10 from a total of 743 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 10% reported a negative effect. |
Onfi has an average rating of 5.7 out of 10 from a total of 12 ratings on Drugs.com. 42% of reviewers reported a positive effect, while 33% reported a negative effect. |
Epidiolex has an average rating of 3.7 out of 10 from a total of 3 ratings on Drugs.com. 0% of reviewers reported a positive effect, while 67% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: Klonopin side effects in more detail. |
See also: Onfi side effects in more detail. |
See also: Epidiolex side effects in more detail. |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all Klonopin prices and generic prices |
View all Onfi prices and generic prices |
View all Epidiolex prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
N/A |
Other clobazam brands include: Sympazan |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
40 hours |
82 hours |
61 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 515 drugs are known to interact with Klonopin:
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A total of 508 drugs are known to interact with Onfi:
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A total of 585 drugs are known to interact with Epidiolex:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
June 04, 1975 |
October 21, 2011 |
June 25, 2018 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.