Ketamine Alternatives Compared
Ketamine | Rexulti | Bupropion |
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Ketamine | Rexulti (brexpiprazole) | Bupropion |
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Prescription only
Prescribed for Depression, Pain, Anesthesia. ketamine may also be used for purposes not listed in this medication guide. |
Prescription only
Rexulti is an atypical antipsychotic that may be used to treat adults with schizophrenia or depression, or used to relieve agitation associated with dementia in Alzheimer's disease. Most people... View more |
Prescription only
Bupropion may be used in the treatment of depression or as an aid to smoking cessation; however, side effects may include insomnia, neuropsychiatric adverse events, or seizures. It carries a black... View more |
Related suggestions Depression
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More about Ketamine | More about Rexulti (brexpiprazole) | More about Bupropion | ||||||||||||||||||||||||
Ratings & Reviews | ||||||||||||||||||||||||||
Ketamine has an average rating of 5.4 out of 10 from a total of 157 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 49% reported a negative effect. |
Rexulti has an average rating of 6.4 out of 10 from a total of 451 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 27% reported a negative effect. |
Bupropion has an average rating of 7.0 out of 10 from a total of 2857 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 20% reported a negative effect. |
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Drug Class | ||||||||||||||||||||||||||
Side Effects | ||||||||||||||||||||||||||
See also: ketamine side effects in more detail. |
See also: Rexulti side effects in more detail. |
See also: bupropion side effects in more detail. |
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Generic Availability | ||||||||||||||||||||||||||
Lower cost generic |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all ketamine prices |
View all Rexulti prices |
View all bupropion prices |
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Dosage Form(s) Available | ||||||||||||||||||||||||||
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Brand Names | ||||||||||||||||||||||||||
Ketalar |
N/A |
Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
1 hour |
91 hours |
30 hours |
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CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | ||||||||||||||||||||||||||
Category N
Not classified
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | ||||||||||||||||||||||||||
A total of 409 drugs are known to interact with ketamine:
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A total of 580 drugs are known to interact with Rexulti:
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A total of 497 drugs are known to interact with bupropion:
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Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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Disease Interactions | ||||||||||||||||||||||||||
First Approval Date | ||||||||||||||||||||||||||
February 19, 1970 |
July 10, 2015 |
December 30, 1985 |
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WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
N/A |
N/A |
N/A |
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More Information | ||||||||||||||||||||||||||
Patient resources | ||||||||||||||||||||||||||
Professional Resources | ||||||||||||||||||||||||||
Related Treatment Guide | ||||||||||||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.