Comparing Hydroxyzine vs Levocetirizine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Hydroxyzine	Levocetirizine	Enter another drug to compare

Hydroxyzine

Levocetirizine

Prescription only

Hydroxyzine may be used to relieve anxiety or itching; however, it causes sedation so can affect a person's ability to drive or operate machinery. It should not be used during pregnancy or while... View more

Prescription and OTC

Prescribed for Urticaria, Allergic Rhinitis, Allergies, Food Allergies. Levocetirizine may also be used for purposes not listed in this medication guide.

More about Hydroxyzine

More about Levocetirizine

Ratings & Reviews

Hydroxyzine has an average rating of 5.9 out of 10 from a total of 1406 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 35% reported a negative effect.

Levocetirizine has an average rating of 5.6 out of 10 from a total of 345 ratings on Drugs.com. 43% of reviewers reported a positive effect, while 40% reported a negative effect.

View all 1406 reviews

View all 345 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Drowsiness (21.8%)
Tiredness (10.5%)
Sleepy (6.3%)
Anxiety (5.6%)
Nausea (3.8%)
Dizziness (3.7%)
Dry mouth (3.1%)

View all Hydroxyzine side effects

Drowsiness (22.3%)
Tiredness (13.9%)
Depression (6.4%)
Fatigue (6.1%)
Anxiety (5.8%)
Itching (5.2%)
Dizziness (4.9%)

View all Levocetirizine side effects

Drug Class

Antihistamines

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	4 tablet
Strength	hydrochloride 25 mg
Per unit^*	$2.74
Cost^*	$10.95

View all Hydroxyzine prices

Quantity	30 tablet
Strength	5 mg
Per unit^*	$0.44 - $1.12
Cost^*	$13.28 - $33.51

View all Levocetirizine prices

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Dosage Forms

Intramuscular solution
Oral capsule
Oral syrup
Oral tablet

Oral solution
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

7 hours

8 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category N Not classified

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 581 drugs are known to interact with Hydroxyzine:

93 major drug interactions (368 brand and generic names)
484 moderate drug interactions (1992 brand and generic names)
4 minor drug interactions (16 brand and generic names)

A total of 254 drugs are known to interact with Levocetirizine:

2 major drug interactions (4 brand and generic names)
250 moderate drug interactions (1081 brand and generic names)
2 minor drug interactions (41 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of hydrOXYzine such as dizziness, drowsiness... View more

Alcohol can increase the nervous system side effects of levocetirizine such as dizziness... View more

Disease Interactions

First Approval Date

April 12, 1956

N/A

WADA Class View classifications

N/A

More Information

Patient Resources

Levocetirizine uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Hydroxyzine vs Levocetirizine

See also:

Paracetamol

Tylenol

Xolair

Lexapro

Xanax

Cymbalta

Zofran

Zyrtec

Ativan

Celebrex

Further information

Comparing Hydroxyzine vs Levocetirizine

See also:

Further information

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